TPX-0131, a Potent CNS-penetrant, Next-generation Inhibitor of Wild-type ALK and ALK-resistant Mutations von Murray, Brion W., Zhai, Dayong, Deng, Wei, Zhang, Xin, Ung, Jane, Nguyen, Vivian, Zhang, Han, Barrera, Maria, Parra, Ana, Cowell, Jessica, Lee, Dong J., Aloysius, Herve, Rogers, Evan

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Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia von Konopleva, Marina, Contractor, Rooha, Tsao, Twee, Samudio, Ismael, Ruvolo, Peter P., Kitada, Shinichi, Deng, Xingming, Zhai, Dayong, Shi, Yue-Xi, Sneed, Thomas, Verhaegen, Monique, Soengas, Maria, Ruvolo, Vivian R., McQueen, Teresa, Schober, Wendy D., Watt, Julie C., Jiffar, Tilahun, Ling, Xiaoyang, Marini, Frank C., Harris, David, Dietrich, Martin, Estrov, Zeev, McCubrey, James, May, W. Stratford, Reed, John C., Andreeff, Michael

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Discovery, Characterization, and Structure−Activity Relationships Studies of Proapoptotic Polyphenols Targeting B-Cell Lymphocyte/Leukemia-2 Proteins von Kitada, Shinichi, Leone, Marilisa, Sareth, Sina, Zhai, Dayong, Reed, John C, Pellecchia, Maurizio

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Humanin peptide suppresses apoptosis by interfering with Bax activation von Reed, John C, Guo, Bin, Zhai, Dayong, Cabezas, Edelmira, Welsh, Kate, Nouraini, Shahrzad, Satterthwait, Arnold C

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Multi-Interference and Multi-Model Dynamic Scheduling of the Small Satellite Based on Dual Population Genetic Algorithm von Hailong Yang, Hailong Yang, Hailong Yang, Tian Xia, Tian Xia, Zeyu Xia, Zeyu Xia, Dayong Zhai

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Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation von Lee, Hyunmi, Rotolo, Jimmy A, Mesicek, Judith, Penate-Medina, Tuula, Rimner, Andreas, Liao, Wen-Chieh, Yin, Xianglei, Ragupathi, Govind, Ehleiter, Desiree, Gulbins, Erich, Zhai, Dayong, Reed, John C, Haimovitz-Friedman, Adriana, Fuks, Zvi, Kolesnick, Richard

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Differential Regulation of Bax and Bak by Anti-apoptotic Bcl-2 Family Proteins Bcl-B and Mcl-1 von Zhai, Dayong, Jin, Chaofang, Huang, Ziwei, Satterthwait, Arnold C., Reed, John C.

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Cancer prevention by tea polyphenols is linked to their direct inhibition of antiapoptotic bcl-2-family proteins von LEONE, Marilisa, DAYONG ZHAI, SARETH, Sina, KITADA, Shinichi, REED, John C, PELLECCHIA, Maurizio

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Vaccinia Virus Virulence Factor N1L is a Novel Promising Target for Antiviral Therapeutic Intervention von Cheltsov, Anton V, Aoyagi, Mika, Aleshin, Alexander, Yu, Eric Chi-Wang, Gilliland, Taylor, Zhai, Dayong, Bobkov, Andrey A, Reed, John C, Liddington, Robert C, Abagyan, Ruben

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Expression, purification, and characterization of recombinant NOD1 (NLRC1): A NLR family member von Askari, Nadav, Correa, Ricardo G., Zhai, Dayong, Reed, John C.

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Mechanism of Bcl-2 and Bcl-XL inhibition of NLRP1 inflammasome: Loop domain-dependent suppression of ATP binding and oligomerization von Faustin, Benjamin, Chen, Ya, Zhai, Dayong, Negrate, Gaelle Le, Lartigue, Lydia, Satterthwait, Arnold, Reed, John C

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Abstract 2132: The novel, rationally-designed, ALK/SRC inhibitor TPX-0005 overcomes multiple acquired resistance mechanisms to current ALK inhibitors von Zhai, Dayong, Deng, Wei, Huang, Zhongdong, Rogers, Evan, Cui, J. Jean

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Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins von Zhai, Dayong, Jin, Chaofang, Shiau, Chung-Wai, Kitada, Shinichi, Satterthwait, Arnold C, Reed, John C

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Heterocyclic α-helix mimetics for targeting protein–protein interactions von Biros, Shannon M., Moisan, Lionel, Mann, Enrique, Carella, Alexandre, Zhai, Dayong, Reed, John C., Rebek, Julius

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Synthetic substrates for measuring activity of autophagy proteases-autophagins (Atg4): Autophagins (Atg4) von Shu, Chih-Wen, Drag, Marcin, Bekes, Miklos, Zhai, Dayong, Salvesen, Guy S., Reed, John C.

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Humanin Binds and Nullifies Bid Activity by Blocking Its Activation of Bax and Bak von Zhai, Dayong, Luciano, Frederic, Zhu, Xiuwen, Guo, Bin, Satterthwait, Arnold C., Reed, John C.

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Apogossypol Derivatives as Pan-Active Inhibitors of Antiapoptotic B-Cell Lymphoma/Leukemia-2 (Bcl-2) Family Proteins von Wei, Jun, Kitada, Shinichi, Rega, Michele F, Stebbins, John L, Zhai, Dayong, Cellitti, Jason, Yuan, Hongbin, Emdadi, Aras, Dahl, Russell, Zhang, Ziming, Yang, Li, Reed, John C, Pellecchia, Maurizio

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Regulation of p53 Localization and Activity by Ubc13 von Laine, Aaron, Topisirovic, Ivan, Zhai, Dayong, Reed, John C., Borden, Katherine L. B., Ronai, Ze'ev

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High-Throughput Fluorescence Assay for Small-Molecule Inhibitors of Autophagins/Atg4 von Shu, Chih-Wen, Madiraju, Charitha, Zhai, Dayong, Welsh, Kate, Diaz, Paul, Sergienko, Eduard, Sano, Renata, Reed, John C.

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Structure-Activity Relationships by Interligand NOE-Based Design and Synthesis of Antiapoptotic Compounds Targeting Bid von Becattini, Barbara, Culmsee, Carsten, Leone, Marilisa, Zhai, Dayong, Zhang, Xiyun, Crowell, Kevin J., Rega, Michele F., Landshamer, Stefan, Reed, John C., Plesnila, Nikolaus, Pellecchia, Maurizio

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