Multiple cells-of-origin of mutant K-Ras–induced mouse lung adenocarcinoma von Sutherland, Kate D., Song, Ji-Ying, Kwon, Min Chul, Proost, Natalie, Zevenhoven, John, Berns, Anton

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High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs von Rottenberg, Sven, Jaspers, Janneke E, Kersbergen, Ariena, van der Burg, Eline, Nygren, Anders O.H, Zander, Serge A.L, Derksen, Patrick W.B, de Bruin, Michiel, Zevenhoven, John, Lau, Alan, Boulter, Robert, Cranston, Aaron, O'Connor, Mark J, Martin, Niall M.B, Borst, Piet, Jonkers, Jos

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Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice von Badhai, Jitendra, Pandey, Gaurav Kumar, Song, Ji-Ying, Krijgsman, Oscar, Bhaskaran, Rajith, Chandrasekaran, Gayathri, Kwon, Min-chul, Bombardelli, Lorenzo, Monkhorst, Kim, Grasso, Cristoforo, Zevenhoven, John, van der Vliet, Jan, Cozijnsen, Miranda, Krimpenfort, Paul, Peeper, Daniel, van Lohuizen, Maarten, Berns, Anton

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Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB von Peeper, Daniel S, Douma, Sirith, van Laar, Theo, Zevenhoven, John, Meuwissen, Ralph, van Garderen, Evert

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Transcription Factor NFIB Is a Driver of Small Cell Lung Cancer Progression in Mice and Marks Metastatic Disease in Patients von Semenova, Ekaterina A., Kwon, Min-chul, Monkhorst, Kim, Song, Ji-Ying, Bhaskaran, Rajith, Krijgsman, Oscar, Kuilman, Thomas, Peters, Dennis, Buikhuisen, Wieneke A., Smit, Egbert F., Pritchard, Colin, Cozijnsen, Miranda, van der Vliet, Jan, Zevenhoven, John, Lambooij, Jan-Paul, Proost, Natalie, van Montfort, Erwin, Velds, Arno, Huijbers, Ivo J., Berns, Anton

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Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model von Meuwissen, Ralph, Linn, Sabine C, Linnoila, R.Ilona, Zevenhoven, John, Mooi, Wolter J, Berns, Anton

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Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis von Desmet, Christophe J., Gallenne, Tristan, Prieur, Alexandre, Reyal, Fabien, Visser, Nils L., Wittner, Ben S., Smit, Marjon A., Geiger, Thomas R., Laoukili, Jamila, Iskit, Sedef, Rodenko, Boris, Zwart, Wilbert, Evers, Bastiaan, Horlings, Hugo, Ajouaou, Abderrahrim, Zevenhoven, John, van Vliet, Martin, Ramaswamy, Sridhar, Wessels, Lodewyk F. A., Peeper, Daniel S.

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Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis von Derksen, Patrick W.B., Liu, Xiaoling, Saridin, Francis, van der Gulden, Hanneke, Zevenhoven, John, Evers, Bastiaan, van Beijnum, Judy R., Griffioen, Arjan W., Vink, Jacqueline, Krimpenfort, Paul, Peterse, Johannes L., Cardiff, Robert D., Berns, Anton, Jonkers, Jos

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Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer von Liu, Xiaoling, Holstege, Henne, van der Gulden, Hanneke, Treur-Mulder, Marcelle, Zevenhoven, John, Velds, Arno, Kerkhoven, Ron M, van Vliet, Martin H, Wessels, Lodewyk F.A, Peterse, Johannes L, Berns, Anton, Jonkers, Jos

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Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer von Nacerddine, Karim, Beaudry, Jean-Bernard, Ginjala, Vasudeva, Westerman, Bart, Mattiroli, Francesca, Song, Ji-Ying, van der Poel, Henk, Ponz, Olga Balagué, Pritchard, Colin, Cornelissen-Steijger, Paulien, Zevenhoven, John, Tanger, Ellen, Sixma, Titia K, Ganesan, Shridar, van Lohuizen, Maarten

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serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish von van der Velden, Yme U, Wang, Liqin, Zevenhoven, John, van Rooijen, Ellen, van Lohuizen, Maarten, Giles, Rachel H, Clevers, Hans, Haramis, Anna-Pavlina G

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The adaptive immune system promotes initiation of prostate carcinogenesis in a human c-Myc transgenic mouse model von Melis, Monique H M, Nevedomskaya, Ekaterina, van Burgsteden, Johan, Cioni, Bianca, van Zeeburg, Hester J T, Song, Ji-Ying, Zevenhoven, John, Hawinkels, Lukas J A C, de Visser, Karin E, Bergman, Andries M

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GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors von Westerman, Bart A, Blom, Marleen, Tanger, Ellen, van der Valk, Martin, Song, Ji-Ying, van Santen, Marije, Gadiot, Jules, Cornelissen-Steijger, Paulien, Zevenhoven, John, Prosser, Haydn M, Uren, Anthony, Aronica, Eleonora, van Lohuizen, Maarten

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An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential von Wang, Liqin, Leite de Oliveira, Rodrigo, Huijberts, Sanne, Bosdriesz, Evert, Pencheva, Nora, Brunen, Diede, Bosma, Astrid, Song, Ji-Ying, Zevenhoven, John, Los-de Vries, G. Tjitske, Horlings, Hugo, Nuijen, Bastiaan, Beijnen, Jos H., Schellens, Jan H.M., Bernards, Rene

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Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours von Krimpenfort, Paul, Song, Ji-Ying, Proost, Natalie, Zevenhoven, John, Jonkers, Jos, Berns, Anton

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Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis von Kwon, Min-chul, Proost, Natalie, Song, Ji-Ying, Sutherland, Kate D, Zevenhoven, John, Berns, Anton

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Bmi1 Controls Tumor Development in an Ink4a/Arf-Independent Manner in a Mouse Model for Glioma von Bruggeman, Sophia W.M., Hulsman, Danielle, Tanger, Ellen, Buckle, Tessa, Blom, Marleen, Zevenhoven, John, van Tellingen, Olaf, van Lohuizen, Maarten

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A Conditional Mouse Model for Malignant Mesothelioma von Jongsma, Johan, van Montfort, Erwin, Vooijs, Marc, Zevenhoven, John, Krimpenfort, Paul, van der Valk, Martin, van de Vijver, Marc, Berns, Anton

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Abstract LB-201: Functional role for tumor heterogeneity: Paracrine signaling between tumor subclones of mouse SCLC promotes metastasis von Kwon, Min Chul, Proost, Natalie, Sutherland, Kate, Zevenhoven, John, Berns, Anton

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Frat is dispensable for canonical Wnt signaling in mammals von van Amerongen, Renée, Nawijn, Martijn, Franca-Koh, Jonathan, Zevenhoven, John, van der Gulden, Hanneke, Jonkers, Jos, Berns, Anton

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