The opposite impact of Janus kinase inhibitor Ruxolitinib on the function of bone marrow mesenchymal stem cells and immune cells in acute GVHD recipients von Zeng, Defu

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IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway von Wang, Lin, Yi, Tangsheng, Kortylewski, Marcin, Pardoll, Drew M, Zeng, Defu, Yu, Hua

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Dual-responsive mesoporous poly-N-isopropylacrylamide-hydroxyapatite composite microspheres for controlled anticancer drug delivery von Zhou, Liang, Zhang, Yulin, Zeng, Defu, Shu, Ting, Wang, Shi

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Regulation of GVHD and GVL Activity via PD-L1 Interaction With PD-1 and CD80 von Cassady, Kaniel, Martin, Paul J, Zeng, Defu

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IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice von Song, Qingxiao, Wang, Xiaoning, Wu, Xiwei, Kang, Tae Hyuk, Qin, Hanjun, Zhao, Dongchang, Jenq, Robert R., van den Brink, Marcel R. M., Riggs, Arthur D., Martin, Paul J., Chen, Yuan-Zhong, Zeng, Defu

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Steroid-Refractory Gut Graft-Versus-Host Disease: What We Have Learned From Basic Immunology and Experimental Mouse Model von Song, Qingxiao, Nasri, Ubaydah, Zeng, Defu

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Growth factors and medium hyperglycemia induce Sox9⁺ ductal cell differentiation into β cells in mice with reversal of diabetes von Zhang, Mingfeng, Lin, Qing, Qi, Tong, Wang, Tiankun, Chen, Ching-Cheng, Riggs, Arthur D., Zeng, Defu

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Antibodies from donor B cells perpetuate cutaneous chronic graft-versus-host disease in mice von Jin, Hua, Ni, Xiong, Deng, Ruishu, Song, Qingxiao, Young, James, Cassady, Kaniel, Zhang, Mingfeng, Forman, Stephen, Martin, Paul J., Liu, Qifa, Zeng, Defu

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Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease von Deng, Ruishu, Hurtz, Christian, Song, Qingxiao, Yue, Chanyu, Xiao, Gang, Yu, Hua, Wu, Xiwei, Muschen, Markus, Forman, Stephen, Martin, Paul J., Zeng, Defu

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Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease von Yi, Tangsheng, Chen, Ying, Wang, Lin, Du, Gong, Huang, Daniel, Zhao, Dongchang, Johnston, Heather, Young, James, Todorov, Ivan, Umetsu, Dale T., Chen, Lieping, Iwakura, Yoichiro, Kandeel, Fouad, Forman, Stephen, Zeng, Defu

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Murine Models Provide New Insights Into Pathogenesis of Chronic Graft- Versus -Host Disease in Humans von Song, Qingxiao, Kong, Xiaohui, Martin, Paul J, Zeng, Defu

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Retention of Donor T Cells in Lymphohematopoietic Tissue and Augmentation of Tissue PD-L1 Protection for Prevention of GVHD While Preserving GVL Activity von Song, Qingxiao, Nasri, Ubaydah, Nakamura, Ryotaro, Martin, Paul J, Zeng, Defu

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Mouse models usher in precision medicine von Zeng, Defu

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microRNA-142 guards against autoimmunity by controlling Treg cell homeostasis and function von Wang, Wei-Le, Ouyang, Ching, Graham, Natalie M, Zhang, Yuankun, Cassady, Kaniel, Reyes, Estefany Y, Xiong, Min, Davis, Alicia M, Tang, Kathie, Zeng, Defu, Boldin, Mark P

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Donor T cell STAT3 deficiency enables tissue PD-L1-dependent prevention of graft-versus-host disease while preserving graft-versus-leukemia activity von Li, Qinjian, Wang, Xiaoqi, Song, Qingxiao, Yang, Shijie, Wu, Xiwei, Yang, Dongyun, Marié, Isabelle J, Qin, Hanjun, Zheng, Moqian, Nasri, Ubaydah, Kong, Xiaohui, Wang, Bixin, Lizhar, Elizabeth, Cassady, Kaniel, Tompkins, Josh, Levy, David, Martin, Paul J, Zhang, Xi, Zeng, Defu

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Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease von Yi, Tangsheng, Zhao, Dongchang, Lin, Chia-Lei, Zhang, Chunyan, Chen, Ying, Todorov, Ivan, LeBon, Thomas, Kandeel, Fouad, Forman, Stephen, Zeng, Defu

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Bridge between type 1 diabetes in mouse and man von Zeng, Defu

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In vivo–activated CD103+CD4+ regulatory T cells ameliorate ongoing chronic graft-versus-host disease von Zhao, Dongchang, Zhang, Chunyan, Yi, Tangsheng, Lin, Chia-Lei, Todorov, Ivan, Kandeel, Fouad, Forman, Stephen, Zeng, Defu

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Newly found arsons ignite the fire of gut GVHD von Zeng, Defu

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HDAC inhibitor reduces cytokine storm and facilitates induction of chimerism that reverses lupus in anti-CD3 conditioning regimen von Li, Nainong, Zhao, Dongchang, Kirschbaum, Mark, Zhang, Chunyan, Lin, Chia-Lei, Todorov, Ivan, Kandeel, Fouad, Forman, Stephen, Zeng, Defu

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