Ranolazine Improves Cardiac Diastolic Dysfunction Through Modulation of Myofilament Calcium Sensitivity von Lovelock, Joshua D, Monasky, Michelle M, Jeong, Euy-Myoung, Lardin, Harvey A, Liu, Hong, Patel, Bindiya G, Taglieri, Domenico M, Gu, Lianzhi, Kumar, Praveen, Pokhrel, Narayan, Zeng, Dewan, Belardinelli, Luiz, Sorescu, Dan, Solaro, R John, Dudley, Samuel C

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Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis von Zhou, Yang, Murthy, Jayasimha N, Zeng, Dewan, Belardinelli, Luiz, Blackburn, Michael R

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If inhibition in the atrioventricular node by ivabradine causes rate-dependent slowing of conduction and reduces ventricular rate during atrial fibrillation von Verrier, Richard L., PhD, Bonatti, Rodolfo, BS, Silva, Ana F.G., BS, Batatinha, Julio A.P., BS, Nearing, Bruce D., PhD, Liu, Gongxin, PhD, Rajamani, Sridharan, PhD, Zeng, Dewan, PhD, Belardinelli, Luiz, MD

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Differential Expression of Adenosine Receptors in Human Endothelial Cells: Role of A2B Receptors in Angiogenic Factor Regulation von Feoktistov, Igor, Goldstein, Anna E, Ryzhov, Sergey, Zeng, Dewan, Belardinelli, Luiz, Voyno-Yasenetskaya, Tatyana, Biaggioni, Italo

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Inhibition of If in the atrioventricular node as a mechanism for dronedarone’s reduction in ventricular rate during atrial fibrillation von Verrier, Richard L., PhD, Sobrado, Marcel F., BS, Pagotto, Vitor P.F., BS, Kanas, Alexandre F., BS, Machado, Ananda D., BS, Varone, Bruno B., BS, Sobrado, Lucas F., BS, Nearing, Bruce D., PhD, Zeng, Dewan, PhD, Belardinelli, Luiz, MD

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Blockade of A2B adenosine receptor reduces left ventricular dysfunction and ventricular arrhythmias 1 week after myocardial infarction in the rat model von Zhang, Hao, MD, PhD, Zhong, Hongyan, PhD, Everett, Thomas H., PhD, FHRS, Wilson, Emily, BS, Chang, Roger, BS, Zeng, Dewan, PhD, Belardinelli, Luiz, MD, Olgin, Jeffrey E., MD, FHRS

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Low doses of ranolazine and dronedarone in combination exert potent protection against atrial fibrillation and vulnerability to ventricular arrhythmias during acute myocardial isch... von Verrier, Richard L., PhD, FACC, Pagotto, Vitor P.F., BS, Kanas, Alexandre F., BS, Sobrado, Marcel F., BS, Nearing, Bruce D., PhD, Zeng, Dewan, PhD, Belardinelli, Luiz, MD

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Discovery of a Novel A2B Adenosine Receptor Antagonist as a Clinical Candidate for Chronic Inflammatory Airway Diseases von Elzein, Elfatih, Kalla, Rao V, Li, Xiaofen, Perry, Thao, Gimbel, Art, Zeng, Dewan, Lustig, David, Leung, Kwan, Zablocki, Jeff

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Ranolazine terminates atrial flutter and fibrillation in a canine model von Bhimani, Ashish A., MD, Yasuda, Tomoo, MD, Sadrpour, Shervin A., MD, Khrestian, Celeen M., BS, Lee, Seungyup, PhD, Zeng, Dewan, PhD, Belardinelli, Luiz, MD, Waldo, Albert L., MD, FHRS

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A dual thrombin receptor system for platelet activation von Coughlin, Shaun R, Kahn, Mark L, Zheng, Yao-Wu, Huang, Wei, Bigornia, Violeta, Zeng, Dewan, Moff, Stephen, Farese, Robert V, Tam, Carmen

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Protease-activated receptor 3 is a second thrombin receptor in humans von Ishihara, Hiroaki, Connolly, Andrew J, Zeng, Dewan, Kahn, Mark L, Wu Zheng, Yao, Timmons, Courtney, Tram, Tracy, Coughlin, Shaun R

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Dronedarone's Inhibition of If Current Is the Primary Mechanism Responsible for Its Bradycardic Effect von SOBRADO, LUCAS F., VARONE, BRUNO B., MACHADO, ANANDA D., NEARING, BRUCE D., ZENG, DEWAN, BELARDINELLI, LUIZ, VERRIER, RICHARD L.

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Selective, high affinity A2B adenosine receptor antagonists : N-1 monosubstituted 8-(pyrazol-4-yl)xanthines von KALLA, Rao V, ELZEIN, Elfatih, PERRY, Thao, XIAOFEN LI, GIMBEL, Art, MING YANG, DEWAN ZENG, ZABLOCKI, Jeff

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Novel 1,3-Disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) Xanthines:  High Affinity and Selective A2B Adenosine Receptor Antagonists von Kalla, Rao V, Elzein, Elfatih, Perry, Thao, Li, Xiaofen, Palle, Venkata, Varkhedkar, Vaibhav, Gimbel, Arthur, Maa, Tennig, Zeng, Dewan, Zablocki, Jeff

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Novel 1,3-dipropyl-8-(1-heteroarylmethyl-1H-pyrazol-4-yl)-xanthine derivatives as high affinity and selective A2B adenosine receptor antagonists von ELZEIN, Elfatih, KALLA, Rao, LEUNG, Kwan, ZABLOCKI, Jeff, XIAOFEN LI, PERRY, Thao, PARKHILL, Eric, PALLE, Venkata, VARKHEDKAR, Vaibahv, GIMBEL, Art, DEWAN ZENG, LUSTIG, David

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Inhibition of human mast cell activation with the novel selective adenosine A2B receptor antagonist 3-isobutyl-8-pyrrolidinoxanthine (IPDX) von FEOKTISTOV, Igor, GARLAND, Emily M, GOLDSTEIN, Anna E, DEWAN ZENG, BELARDINELLI, Luiz, WELLS, Jack N, BIAGGIONI, Italo

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Phase I, Open-Label, Dose-Escalation/Dose-Expansion Study of Lifirafenib (BGB-283), an RAF Family Kinase Inhibitor, in Patients With Solid Tumors von Desai, Jayesh, Gan, Hui, Barrow, Catherine, Jameson, Michael, Atkinson, Victoria, Haydon, Andrew, Millward, Michael, Begbie, Stephen, Brown, Michael, Markman, Ben, Patterson, William, Hill, Andrew, Horvath, Lisa, Nagrial, Adnan, Richardson, Gary, Jackson, Christopher, Friedlander, Michael, Parente, Phillip, Tran, Ben, Wang, Lai, Chen, Yunxin, Tang, Zhiyu, Huang, Wendy, Wu, John, Zeng, Dewan, Luo, Lusong, Solomon, Benjamin

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The HARMONY Trial: Combined Ranolazine and Dronedarone in the Management of Paroxysmal Atrial Fibrillation: Mechanistic and Therapeutic Synergism von Reiffel, James A, Camm, A John, Belardinelli, Luiz, Zeng, Dewan, Karwatowska-Prokopczuk, Ewa, Olmsted, Ann, Zareba, Wojciech, Rosero, Spencer, Kowey, Peter

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Heparin attenuates symptoms and mast cell degranulation induced by AMP nasal provocation von Zeng, Dewan, Prosperini, Gaetano, Russo, Cristina, Spicuzza, Lucia, Cacciola, Rosella R, Di Maria, Guiseppe U, Polosa, Riccardo

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Phase 1/2 study investigating safety, tolerability, pharmacokinetics, and preliminary antitumor activity of anti-PD-L1 monoclonal antibody bgb-A333 alone and in combination with an... von Desai, Jayesh, Voskoboynik, Mark, Markman, Ben, Hou, Jeannie, Zeng, Dewan, Meniawy, Tarek

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