Characterizing the heterogeneity of tumor tissues from spatially resolved molecular measures von Graf, John F, Zavodszky, Maria I

Volltext

Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases von de Klein, Niek, Tsai, Ellen A., Vochteloo, Martijn, Baird, Denis, Huang, Yunfeng, Chen, Chia-Yen, van Dam, Sipko, Oelen, Roy, Deelen, Patrick, Bakker, Olivier B., El Garwany, Omar, Ouyang, Zhengyu, Marshall, Eric E., Zavodszky, Maria I., van Rheenen, Wouter, Bakker, Mark K., Veldink, Jan, Gaunt, Tom R., Runz, Heiko, Franke, Lude, Westra, Harm-Jan

Volltext

Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas von Berens, Michael E, Sood, Anup, Barnholtz-Sloan, Jill S, Graf, John F, Cho, Sanghee, Kim, Seungchan, Kiefer, Jeffrey, Byron, Sara A, Halperin, Rebecca F, Nasser, Sara, Adkins, Jonathan, Cuyugan, Lori, Devine, Karen, Ostrom, Quinn, Couce, Marta, Wolansky, Leo, McDonough, Elizabeth, Schyberg, Shannon, Dinn, Sean, Sloan, Andrew E, Prados, Michael, Phillips, Joanna J, Nelson, Sarah J, Liang, Winnie S, Al-Kofahi, Yousef, Rusu, Mirabela, Zavodszky, Maria I, Ginty, Fiona

Volltext

Characterizing the composition of iPSC derived cells from bulk transcriptomics data with CellMap von Ouyang, Zhengyu, Bourgeois-Tchir, Nathanael, Lyashenko, Eugenia, Cundiff, Paige E., Cullen, Patrick F., Challa, Ravi, Li, Kejie, Zhang, Xinmin, Casey, Fergal, Engle, Sandra J., Zhang, Baohong, Zavodszky, Maria I.

Volltext

In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model von Chen, Yi A., Kankel, Mark W., Hana, Sam, Lau, Shukkwan Kelly, Zavodszky, Maria I., McKissick, Olivia, Mastrangelo, Nicole, Dion, Jessica, Wang, Bin, Ferretti, Daniel, Koske, David, Lehman, Sydney, Koszka, Kathryn, McLaughlin, Helen, Liu, Mei, Marshall, Eric, Fabian, Attila J., Cullen, Patrick, Marsh, Galina, Hamann, Stefan, Craft, Michael, Sebalusky, Jennifer, Arnold, H. Moore, Driscoll, Rachelle, Sheehy, Adam, Luo, Yi, Manca, Sonia, Carlile, Thomas, Sun, Chao, Sigrist, Kirsten, McCampbell, Alexander, Henderson, Christopher E., Lo, Shih-Ching

Volltext

RNASequest: An End-to-End Reproducible RNAseq Data Analysis and Publishing Framework von Zhu, Jing, Sun, Yu H., Ouyang, Zhengyu, Li, Kejie, Negi, Soumya, Piya, Sarbottam, Hu, Wenxing, Zavodszky, Maria I., Yalamanchili, Hima, Chen, Yirui, Zhang, Xinmin, Casey, Fergal, Zhang, Baohong

Volltext

scRNASequest: an ecosystem of scRNA-seq analysis, visualization, and publishing von Li, Kejie, Sun, Yu H, Ouyang, Zhengyu, Negi, Soumya, Gao, Zhen, Zhu, Jing, Wang, Wanli, Chen, Yirui, Piya, Sarbottam, Hu, Wenxing, Zavodszky, Maria I, Yalamanchili, Hima, Cao, Shaolong, Gehrke, Andrew, Sheehan, Mark, Huh, Dann, Casey, Fergal, Zhang, Xinmin, Zhang, Baohong

Volltext

Computational de novo discovery of distinguishing genes for biological processes and cell types in complex tissues von Newberg, Lee A, Chen, Xiaowei, Kodira, Chinnappa D, Zavodszky, Maria I

Volltext

Side‐chain flexibility in protein–ligand binding: The minimal rotation hypothesis von Zavodszky, Maria I., Kuhn, Leslie A.

Volltext

Dorsal root ganglion toxicity after AAV intra-CSF delivery of a RNAi expression construct into non-human primates and mice von Hawley, Zachary C.E., Pardo, Ingrid D., Cao, Shaolong, Zavodszky, Maria I., Casey, Fergal, Ferber, Kyle, Luo, Yi, Hana, Sam, Chen, Shukkwan K., Doherty, Jessica, Costa, Raquel, Cullen, Patrick, Liu, Yuqing, Carlile, Thomas M., Chowdhury, Twinkle, Doyle, Benjamin, Clarner, Pete, Mangaudis, Kevin, Guilmette, Edward, Bourque, Shawn, Koske, David, Nadella, Murali V.P., Trapa, Patrick, Hawes, Michael L., Raitcheva, Denitza, Lo, Shih-Ching

Volltext

Efficacy and safety of a SOD1-targeting artificial miRNA delivered by AAV9 in mice are impacted by miRNA scaffold selection von Lau, Shukkwan K., Hawley, Zachary C.E., Zavodszky, Maria I., Hana, Sam, Ferretti, Daniel, Grubor, Branka, Hawes, Michael, Xu, Shanqin, Hamann, Stefan, Marsh, Galina, Cullen, Patrick, Challa, Ravi, Carlile, Thomas M., Zhang, Hang, Lee, Wan-Hung, Peralta, Andrea, Clarner, Pete, Wei, Cong, Koszka, Kathryn, Gao, Feng, Lo, Shih-Ching

Volltext

Synergistic Cooperation between Two ClpB Isoforms in Aggregate Reactivation von Nagy, Maria, Guenther, Izabela, Akoyev, Vladimir, Barnett, Micheal E., Zavodszky, Maria I., Kedzierska-Mieszkowska, Sabina, Zolkiewski, Michal

Volltext

OmicsView: Omics data analysis through interactive visual analytics von Casey, Fergal, Negi, Soumya, Zhu, Jing, Sun, Yu H., Zavodszky, Maria, Cheng, Derrick, Lin, Dongdong, John, Sally, Penny, Michelle A., Sexton, David, Zhang, Baohong

Volltext

Structure-activity relationship of nerve-highlighting fluorophores von Gibbs, Summer L, Xie, Yang, Goodwill, Haley L, Nasr, Khaled A, Ashitate, Yoshitomo, Madigan, Victoria J, Siclovan, Tiberiu M, Zavodszky, Maria, Tan Hehir, Cristina A, Frangioni, John V

Volltext

Emerging understanding of multiscale tumor heterogeneity von Gerdes, Michael J, Sood, Anup, Sevinsky, Christopher, Pris, Andrew D, Zavodszky, Maria I, Ginty, Fiona

Volltext

Synthetic curcuminoids modulate the arachidonic acid metabolism of human platelet 12-lipoxygenase and reduce sprout formation of human endothelial cells von Jankun, Jerzy, Aleem, Ansari M, Malgorzewicz, Sylvia, Szkudlarek, Maria, Zavodszky, Maria I, Dewitt, David L, Feig, Michael, Selman, Steven H, Skrzypczak-Jankun, Ewa

Volltext

Modeling correlated main-chain motions in proteins for flexible molecular recognition von Zavodszky, Maria I., Lei, Ming, Thorpe, M. F., Day, Anthony R., Kuhn, Leslie A.

Volltext

BioDMET: a physiologically based pharmacokinetic simulation tool for assessing proposed solutions to complex biological problems von Graf, John F., Scholz, Bernhard J., Zavodszky, Maria I.

Volltext

Sampling protein conformations and pathways von Lei, Ming, Zavodszky, Maria I., Kuhn, Leslie A., Thorpe, M. F.

Volltext

Scoring ligand similarity in structure-based virtual screening von Zavodszky, Maria I., Rohatgi, Anjali, Van Voorst, Jeffrey R., Yan, Honggao, Kuhn, Leslie A.

Volltext