Invention of novel 3-aminopiperidin-2-ones as calcitonin gene-related peptide receptor antagonists von Staas, Donnette D., Bell, Ian M., Burgey, Christopher S., Deng, James Z., Gallicchio, Steven N., Lim, John J., Paone, Daniel V., Potteiger, Craig M., Shaw, Anthony W., Stevenson, Heather, Stump, Craig A., Blair Zartman, C., Moore, Eric L., Bruno, Joseph G., Mosser, Scott D., White, Rebecca B., Kane, Stefanie A., Salvatore, Christopher A., Graham, Samuel L., Williams, Theresa M., Selnick, Harold G., Fraley, Mark E.

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MK-8825: A potent and selective CGRP receptor antagonist with good oral activity in rats von Bell, Ian M., Stump, Craig A., Gallicchio, Steven N., Staas, Donnette D., Zartman, C. Blair, Moore, Eric L., Sain, Nova, Urban, Mark, Bruno, Joseph G., Calamari, Amy, Kemmerer, Amanda L., Mosser, Scott D., Fandozzi, Christine, White, Rebecca B., Zrada, Matthew M., Selnick, Harold G., Graham, Samuel L., Vacca, Joseph P., Kane, Stefanie A., Salvatore, Christopher A.

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The discovery of highly potent CGRP receptor antagonists von Stump, Craig A., Bell, Ian M., Bednar, Rodney A., Bruno, Joseph G., Fay, John F., Gallicchio, Steven N., Johnston, Victor K., Moore, Eric L., Mosser, Scott D., Quigley, Amy G., Salvatore, Christopher A., Theberge, Cory R., Blair Zartman, C., Zhang, Xu-Fang, Kane, Stefanie A., Graham, Samuel L., Vacca, Joseph P., Williams, Theresa M.

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Identification of a novel RAMP-independent CGRP receptor antagonist von Zartman, C. Blair, Bell, Ian M., Gallicchio, Steven N., Graham, Samuel L., Kane, Stefanie A., Mallee, John J., Rutledge, Ruth Z., Salvatore, Christopher A., Vacca, Joseph P., Williams, Theresa M.

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Identification and Pharmacological Characterization of Domains Involved in Binding of CGRP Receptor Antagonists to the Calcitonin-like Receptor von Salvatore, Christopher A, Mallee, John J, Bell, Ian M, Zartman, C. Blair, Williams, Theresa M, Koblan, Kenneth S, Kane, Stefanie A

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The identification of potent, orally bioavailable tricyclic CGRP receptor antagonists von Bell, Ian M., Bednar, Rodney A., Corcoran, Halea A., Fay, John F., Gallicchio, Steven N., Johnston, Victor K., Hershey, James C., Miller-Stein, Cynthia M., Moore, Eric L., Mosser, Scott D., Roller, Shane A., Salvatore, Christopher A., Theberge, Cory R., Wong, Bradley K., Blair Zartman, C., Kane, Stefanie A., Williams, Theresa M., Graham, Samuel L., Vacca, Joseph P.

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Discovery of MK-3207: A Highly Potent, Orally Bioavailable CGRP Receptor Antagonist von Bell, Ian M, Gallicchio, Steven N, Wood, Michael R, Quigley, Amy G, Stump, Craig A, Zartman, C. Blair, Fay, John F, Li, Chi-Chung, Lynch, Joseph J, Moore, Eric L, Mosser, Scott D, Prueksaritanont, Thomayant, Regan, Christopher P, Roller, Shane, Salvatore, Christopher A, Kane, Stefanie A, Vacca, Joseph P, Selnick, Harold G

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Non-peptide calcitonin gene-related peptide receptor antagonists from a benzodiazepinone lead von Williams, Theresa M., Stump, Craig A., Nguyen, Diem N., Quigley, Amy G., Bell, Ian M., Gallicchio, Steven N., Zartman, C. Blair, Wan, Bang-Lin, Penna, Kimberly Della, Kunapuli, Priya, Kane, Stefanie A., Koblan, Ken S., Mosser, Scott D., Rutledge, Ruth Z., Salvatore, Christopher, Fay, John F., Vacca, Joseph P., Graham, Samuel L.

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[11C]MK-4232: The First Positron Emission Tomography Tracer for the Calcitonin Gene-Related Peptide Receptor von Bell, Ian M, Gallicchio, Steven N, Stump, Craig A, Bruno, Joseph G, Fan, Hong, Gantert, Liza T, Hostetler, Eric D, Kemmerer, Amanda L, McWherter, Melody, Moore, Eric L, Mosser, Scott D, Purcell, Mona L, Riffel, Kerry, Salvatore, Christopher A, Sanabria-Bohórquez, Sandra, Staas, Donnette D, White, Rebecca B, Williams, Mangay, Zartman, C. Blair, Cook, Jacquelynn J, Hargreaves, Richard J, Kane, Stefanie A, Graham, Samuel L, Selnick, Harold G

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3-Aminopyrrolidinone Farnesyltransferase Inhibitors:  Design of Macrocyclic Compounds with Improved Pharmacokinetics and Excellent Cell Potency von Bell, Ian M, Gallicchio, Steven N, Abrams, Marc, Beese, Lorena S, Beshore, Douglas C, Bhimnathwala, Hema, Bogusky, Michael J, Buser, Carolyn A, Culberson, J. Christopher, Davide, Joseph, Ellis-Hutchings, Michelle, Fernandes, Christine, Gibbs, Jackson B, Graham, Samuel L, Hamilton, Kelly A, Hartman, George D, Heimbrook, David C, Homnick, Carl F, Huber, Hans E, Huff, Joel R, Kassahun, Kelem, Koblan, Kenneth S, Kohl, Nancy E, Lobell, Robert B, Lynch, Joseph J, Robinson, Ronald, Rodrigues, A. David, Taylor, Jeffrey S, Walsh, Eileen S, Williams, Theresa M, Zartman, C. Blair

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Identification of novel, orally bioavailable spirohydantoin CGRP receptor antagonists von Bell, Ian M., Bednar, Rodney A., Fay, John F., Gallicchio, Steven N., Hochman, Jerome H., McMasters, Daniel R., Miller-Stein, Cynthia, Moore, Eric L., Mosser, Scott D., Pudvah, Nicole T., Quigley, Amy G., Salvatore, Christopher A., Stump, Craig A., Theberge, Cory R., Wong, Bradley K., Zartman, C. Blair, Zhang, Xu-Fang, Kane, Stefanie A., Graham, Samuel L., Vacca, Joseph P., Williams, Theresa M.

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Potent benzimidazolone-based CGRP receptor antagonists von THEBERGE, Cory R, BEDNAR, Rodney A, WILLIAMS, Theresa M, ZARTMAN, C. Blair, ZHANG, Xu-Fang, GRAHAM, Samuel L, VACCA, Joseph P, BELL, Ian M, CORCORAN, Halea A, FAY, John F, HERSHEY, James C, JOHNSTON, Victor K, KANE, Stefanie A, MOSSER, Scott, SALVATORE, Christopher A

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Identification of potent, highly constrained CGRP receptor antagonists von Stump, Craig A., Bell, Ian M., Bednar, Rodney A., Fay, John F., Gallicchio, Steven N., Hershey, James C., Jelley, Richard, Kreatsoulas, Constantine, Moore, Eric L., Mosser, Scott D., Quigley, Amy G., Roller, Shane A., Salvatore, Christopher A., Sharik, Steven S., Theberge, Cory R., Zartman, C. Blair, Kane, Stefanie A., Graham, Samuel L., Selnick, Harold G., Vacca, Joseph P., Williams, Theresa M.

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Biochemical and Structural Characterization of a Novel Class of Inhibitors of the Type 1 Insulin-like Growth Factor and Insulin Receptor Kinases von Bell, Ian M, Stirdivant, Steven M, Ahern, Janet, Culberson, J. Christopher, Darke, Paul L, Dinsmore, Christopher J, Drakas, Robert A, Gallicchio, Steven N, Graham, Samuel L, Heimbrook, David C, Hall, Dawn L, Hua, Jin, Kett, Nathan R, Kim, Annette S, Kornienko, Maria, Kuo, Lawrence C, Munshi, Sanjeev K, Quigley, Amy G, Reid, John C, Trotter, B. Wesley, Waxman, Lloyd H, Williams, Theresa M, Zartman, C. Blair

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N-Arylpiperazinone Inhibitors of Farnesyltransferase:  Discovery and Biological Activity von Williams, Theresa M, Bergman, Jeffrey M, Brashear, Karen, Breslin, Michael J, Dinsmore, Christopher J, Hutchinson, John H, MacTough, Suzanne C, Stump, Craig A, Wei, Donna D, Zartman, C. Blair, Bogusky, Michael J, Culberson, J. Christopher, Buser-Doepner, Carolyn, Davide, Joseph, Greenberg, Ian B, Hamilton, Kelly A, Koblan, Kenneth S, Kohl, Nancy E, Liu, Dongming, Lobell, Robert B, Mosser, Scott D, O'Neill, Timothy J, Rands, Elaine, Schaber, Michael D, Wilson, Francine, Senderak, Edith, Motzel, Sherri L, Gibbs, Jackson B, Graham, Samuel L, Heimbrook, David C, Hartman, George D, Oliff, Allen I, Huff, Joel R

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Selective electrolytic fluorinations in 70% HF/30% pyridine von Lee, Sarah M., Roseman, Jamie M., Blair Zartman, C., Morrison, Eamonn P., Harrison, Sean J., Stankiewicz, Corrie A., Middleton, W.J.

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Acetonitrile/water gas-phase reaction products observed by use of atmospheric pressure chemical ionization: adducts formed with sulfonamides von Ross III, Charles W., Coddington, Arthur B., Murphy, Joan S., Wisnoski, David D., Zartman, C. Blair, Ramjit, Harri G.

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Macrocyclic piperazinones as potent dual inhibitors of farnesyltransferase and geranylgeranyltransferase-I von Dinsmore, Christopher J, Zartman, C.Blair, Bergman, Jeffrey M, Abrams, Marc T, Buser, Carolyn A, Culberson, J.Christopher, Davide, Joseph P, Ellis-Hutchings, Michelle, Fernandes, Christine, Graham, Samuel L, Hartman, George D, Huber, Hans E, Lobell, Robert B, Mosser, Scott D, Robinson, Ronald G, Williams, Theresa M

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Conformational Restriction of Flexible Ligands Guided by the Transferred NOE Experiment:  Potent Macrocyclic Inhibitors of Farnesyltransferase von Dinsmore, Christopher J, Bogusky, Michael J, Culberson, J. Christopher, Bergman, Jeffrey M, Homnick, Carl F, Zartman, C. Blair, Mosser, Scott D, Schaber, Michael D, Robinson, Ronald G, Koblan, Kenneth S, Huber, Hans E, Graham, Samuel L, Hartman, George D, Huff, Joel R, Williams, Theresa M

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Arylmethanesulfonates are convenient latent phenols in the nucleophilic aromatic substitution reaction von Dinsmore, Christopher J., Zartman, C.Blair

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