Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy von Picarda, Elodie, Ohaegbulam, Kim C, Zang, Xingxing

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Wide Expression and Significance of Alternative Immune Checkpoint Molecules, B7x and HHLA2, in PD-L1-Negative Human Lung Cancers von Cheng, Haiying, Borczuk, Alain, Janakiram, Murali, Ren, Xiaoxin, Lin, Juan, Assal, Amer, Halmos, Balazs, Perez-Soler, Roman, Zang, Xingxing

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The third group of the B7‐CD28 immune checkpoint family: HHLA2, TMIGD2, B7x, and B7‐H3 von Janakiram, Murali, Shah, Urvi A., Liu, Weifeng, Zhao, Aimin, Schoenberg, Mark P., Zang, Xingxing

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Cell–cell contact with proinflammatory macrophages enhances the immunotherapeutic effect of mesenchymal stem cells in two abortion models von Li, Yanhong, Zhang, Di, Xu, Ling, Dong, Lin, Zheng, Ji, Lin, Yikong, Huang, Jiefang, Zhang, Yanyun, Tao, Yu, Zang, Xingxing, Li, Dajin, Du, Meirong

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The immune checkpoint B7x expands tumor-infiltrating Tregs and promotes resistance to anti-CTLA-4 therapy von John, Peter, Pulanco, Marc C., Galbo, Phillip M., Wei, Yao, Ohaegbulam, Kim C., Zheng, Deyou, Zang, Xingxing

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The B7 Family and Cancer Therapy: Costimulation and Coinhibition von XINGXING ZANG, ALLISON, James P

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Immune checkpoint blockade and CAR-T cell therapy in hematologic malignancies von Wang, Hao, Kaur, Gurbakhash, Sankin, Alexander I, Chen, Fuxiang, Guan, Fangxia, Zang, Xingxing

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New immunotherapies targeting the PD-1 pathway von Chinai, Jordan M, Janakiram, Murali, Chen, Fuxiang, Chen, Wantao, Kaplan, Mark, Zang, Xingxing

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HHLA2, a New Immune Checkpoint Member of the B7 Family, Is Widely Expressed in Human Lung Cancer and Associated with EGFR Mutational Status von Cheng, Haiying, Janakiram, Murali, Borczuk, Alain, Lin, Juan, Qiu, Wanglong, Liu, Huijie, Chinai, Jordan M, Halmos, Balazs, Perez-Soler, Roman, Zang, Xingxing

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Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma von Koirala, Pratistha, Roth, Michael E., Gill, Jonathan, Piperdi, Sajida, Chinai, Jordan M., Geller, David S., Hoang, Bang H., Park, Amy, Fremed, Michael A., Zang, Xingxing, Gorlick, Richard

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B7-H4(B7x)-Mediated Cross-talk between Glioma-Initiating Cells and Macrophages via the IL6/JAK/STAT3 Pathway Lead to Poor Prognosis in Glioma Patients von Yao, Yu, Ye, Hongxing, Qi, Zengxin, Mo, Lianjie, Yue, Qi, Baral, Aparajita, Hoon, Dave S B, Vera, Juan Carlos, Heiss, John D, Chen, Clark C, Zhang, Jianmin, Jin, Kunlin, Wang, Ying, Zang, Xingxing, Mao, Ying, Zhou, Liangfu

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The Contrasting Role of B7-H3 von Hofmeyer, Kimberly A., Ray, Anjana, Zang, Xingxing

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HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function von Zhao, Ruihua, Chinai, Jordan M., Buhl, Susan, Scandiuzzi, Lisa, Ray, Anjana, Jeon, Hyungjun, Ohaegbulam, Kim C., Ghosh, Kaya, Zhao, Aimin, Scharff, Matthew D., Zang, Xingxing

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Expression, Clinical Significance, and Receptor Identification of the Newest B7 Family Member HHLA2 Protein von Janakiram, Murali, Chinai, Jordan M, Fineberg, Susan, Fiser, Andras, Montagna, Cristina, Medavarapu, Ramadevi, Castano, Ekaterina, Jeon, Hyungjun, Ohaegbulam, Kim C, Zhao, Ruihua, Zhao, Aimin, Almo, Steven C, Sparano, Joseph A, Zang, Xingxing

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The appropriate frequency and function of decidual Tim-3+CTLA-4+CD8+ T cells are important in maintaining normal pregnancy von Wang, Songcun, Sun, Fengrun, Li, Mengdie, Qian, Jinfeng, Chen, Chunqin, Wang, Mingyan, Zang, Xingxing, Li, Dajin, Yu, Min, Du, Meirong

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Blockade of the immunosuppressive KIR2DL5/PVR pathway elicits potent human NK cell–mediated antitumor immunity von Ren, Xiaoxin, Peng, Mou, Xing, Peng, Wei, Yao, Galbo, Phillip M., Corrigan, Devin, Wang, Hao, Su, Yingzhen, Dong, Xiaoshen, Sun, Qizhe, Li, Yixian, Zhang, Xiaoyu, Edelmann, Winfried, Zheng, Deyou, Zang, Xingxing

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Macrophage plasticity and function in cancer and pregnancy von Yin, Tingxuan, Li, Xinyi, Li, Yanhong, Zang, Xingxing, Liu, Lu, Du, Meirong

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Checkpoint regulator B7x is epigenetically regulated by HDAC3 and mediates resistance to HDAC inhibitors by reprogramming the tumor immune environment in colorectal cancer von Li, Yuxin, Liu, Yao, Zhao, Na, Yang, Xiaojun, Li, Yaqing, Zhai, Fangzheng, Zang, Xingxing, Cui, Wei

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TMIGD2 is an orchestrator and therapeutic target on human acute myeloid leukemia stem cells von Wang, Hao, Sica, R. Alejandro, Kaur, Gurbakhash, Galbo, Phillip M., Jing, Zhixin, Nishimura, Christopher D., Ren, Xiaoxin, Tanwar, Ankit, Etemad-Gilbertson, Bijan, Will, Britta, Zheng, Deyou, Fooksman, David, Zang, Xingxing

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Blockade of CTLA-4 and Tim-3 pathways induces fetal loss with altered cytokine profiles by decidual CD4+T cells von Wang, Songcun, Chen, Chunqin, Li, Mengdie, Qian, Jinfeng, Sun, Fengyun, Li, Yunyun, Yu, Min, Wang, Mingyan, Zang, Xingxing, Zhu, Rui, Li, Dajin, Du, Meirong

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