A human cell atlas of fetal gene expression von Cao, Junyue, O'Day, Diana R, Pliner, Hannah A, Kingsley, Paul D, Deng, Mei, Daza, Riza M, Zager, Michael A, Aldinger, Kimberly A, Blecher-Gonen, Ronnie, Zhang, Fan, Spielmann, Malte, Palis, James, Doherty, Dan, Steemers, Frank J, Glass, Ian A, Trapnell, Cole, Shendure, Jay

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A human cell atlas of fetal chromatin accessibility von Domcke, Silvia, Hill, Andrew J, Daza, Riza M, Cao, Junyue, O'Day, Diana R, Pliner, Hannah A, Aldinger, Kimberly A, Pokholok, Dmitry, Zhang, Fan, Milbank, Jennifer H, Zager, Michael A, Glass, Ian A, Steemers, Frank J, Doherty, Dan, Trapnell, Cole, Cusanovich, Darren A, Shendure, Jay

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Integrated analysis of multimodal single-cell data von Hao, Yuhan, Hao, Stephanie, Andersen-Nissen, Erica, Mauck, William M., Zheng, Shiwei, Butler, Andrew, Lee, Maddie J., Wilk, Aaron J., Darby, Charlotte, Zager, Michael, Hoffman, Paul, Stoeckius, Marlon, Papalexi, Efthymia, Mimitou, Eleni P., Jain, Jaison, Srivastava, Avi, Stuart, Tim, Fleming, Lamar M., Yeung, Bertrand, Rogers, Angela J., McElrath, Juliana M., Blish, Catherine A., Gottardo, Raphael, Smibert, Peter, Satija, Rahul

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Sources of inter-individual variability leading to significant changes in anti-PD-1 and anti-PD-L1 efficacy identified in mouse tumor models using a QSP framework von Leete, Jessica C, Zager, Michael G, Musante, Cynthia J, Shtylla, Blerta, Qiao, Wenlian

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A kinase to cytokine explorer to identify molecular regulators and potential therapeutic opportunities von Chan, Marina, Kang, Yuqi, Osborne, Shannon, Zager, Michael, Gujral, Taranjit S

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Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth von Murray, Brion W, Guo, Chuangxing, Piraino, Joseph, Westwick, John K, Zhang, Cathy, Lamerdin, Jane, Dagostino, Eleanor, Knighton, Daniel, Loi, Cho-Ming, Zager, Michael, Kraynov, Eugenia, Popoff, Ian, Christensen, James G, Martinez, Ricardo, Kephart, Susan E, Marakovits, Joseph, Karlicek, Shannon, Bergqvist, Simon, Smeal, Tod

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Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery von Cimino, Patrick J, Zager, Michael, McFerrin, Lisa, Wirsching, Hans-Georg, Bolouri, Hamid, Hentschel, Bettina, von Deimling, Andreas, Jones, David, Reifenberger, Guido, Weller, Michael, Holland, Eric C

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Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19 von Su, Yapeng, Chen, Daniel, Yuan, Dan, Lausted, Christopher, Choi, Jongchan, Dai, Chengzhen L., Voillet, Valentin, Duvvuri, Venkata R., Scherler, Kelsey, Troisch, Pamela, Baloni, Priyanka, Qin, Guangrong, Smith, Brett, Kornilov, Sergey A., Rostomily, Clifford, Xu, Alex, Li, Jing, Dong, Shen, Rothchild, Alissa, Zhou, Jing, Murray, Kim, Edmark, Rick, Hong, Sunga, Heath, John E., Earls, John, Zhang, Rongyu, Xie, Jingyi, Li, Sarah, Roper, Ryan, Jones, Lesley, Zhou, Yong, Rowen, Lee, Liu, Rachel, Mackay, Sean, O’Mahony, D. Shane, Dale, Christopher R., Wallick, Julie A., Algren, Heather A., Zager, Michael A., Wei, Wei, Price, Nathan D., Huang, Sui, Subramanian, Naeha, Wang, Kai, Magis, Andrew T., Hadlock, Jenn J., Hood, Leroy, Aderem, Alan, Bluestone, Jeffrey A., Lanier, Lewis L., Greenberg, Philip D., Gottardo, Raphael, Davis, Mark M., Goldman, Jason D., Heath, James R.

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A multiscale, mechanism-driven, dynamic model for the effects of 5α-reductase inhibition on prostate maintenance von Zager, Michael G, Barton, Hugh A

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Chemogenetic evaluation of the mitotic kinesin CENP-E reveals a critical role in triple-negative breast cancer von Kung, Pei-Pei, Martinez, Ricardo, Zhu, Zhou, Zager, Michael, Blasina, Alessandra, Rymer, Isha, Hallin, Jill, Xu, Meirong, Carroll, Christopher, Chionis, John, Wells, Peter, Kozminski, Kirk, Fan, Jeffery, Guicherit, Oivin, Huang, Buwen, Cui, Mei, Liu, Chaoting, Huang, Zhongdong, Sistla, Anand, Yang, Jennifer, Murray, Brion W

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Model‐informed drug development of voxelotor in sickle cell disease: Population pharmacokinetics in whole blood and plasma von Savic, Radojka M., Green, Michelle L., Jorga, Karin, Zager, Michael, Washington, Carla B.

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Defining cellular population dynamics at single-cell resolution during prostate cancer progression von Germanos, Alexandre A, Arora, Sonali, Zheng, Ye, Goddard, Erica T, Coleman, Ilsa M, Ku, Anson T, Wilkinson, Scott, Song, Hanbing, Brady, Nicholas J, Amezquita, Robert A, Zager, Michael, Long, Annalysa, Yang, Yu Chi, Bielas, Jason H, Gottardo, Raphael, Rickman, David S, Huang, Franklin W, Ghajar, Cyrus M, Nelson, Peter S, Sowalsky, Adam G, Setty, Manu, Hsieh, Andrew C

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Preclinical PK/PD modeling and human efficacious dose projection for a glucokinase activator in the treatment of diabetes von Zager, Michael G., Kozminski, Kirk, Pascual, Bernadette, Ogilvie, Kathleen M., Sun, Shaoxian

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Mathematical model for the androgenic regulation of the prostate in intact and castrated adult male rats von Potter, Laura K, Zager, Michael G, Barton, Hugh A

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Single-cell immunology of SARS-CoV-2 infection von Tian, Yuan, Carpp, Lindsay N., Miller, Helen E. R., Zager, Michael, Newell, Evan W., Gottardo, Raphael

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Singular insights into the immunology of SARS-CoV-2 infection von Tian, Yuan, Carpp, Lindsay N., Miller, Helen E.R., Zager, Michael, Newell, Evan W., Gottardo, Raphael

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A kinase to cytokine explorer to identify molecular regulators and potential therapeutic opportunities von Chan, Marina, Kang, Yuqi, Osborne, Shannon, Zager, Michael, Gujral, Taranjit S

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TMOD-30. NTRK2 SPLICE VARIANT, TRKB.T1, LINKS NEUROBIOLOGY, EMBRYONIC DEVELOPMENT, AND ONCOGENESIS von Pattwell, Siobhan, Arora, Sonali, Nuechterlein, Nicholas, Zager, Michael, Loeb, Keith, Cimino, Patrick, Holland, Nikolas, Bolouri, Hamid, Ozawa, Tatsuya, Haffner, Michael, Cao, Junyue, Shendure, Jay, Holland, Eric

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Delayed Nonlinear PBPK Model for Genistein Dosimetry in Rats von Zager, Michael G, Schlosser, Paul M, Tran, Hien T

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Analysis and visualization of linked molecular and clinical cancer data by using Oncoscape von McFerrin, Lisa G., Zager, Michael, Zhang, Jianan, Krenn, Gretchen, McDermott, Robert, Horse-Grant, Desert, Silgard, Emily, Colevas, Kara, Shannon, Paul, Bolouri, Hamid, Holland, Eric C.

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