Incorporating and interpreting regulatory guidance on estimands in diabetes clinical trials: The PIONEER 1 randomized clinical trial as an example von Aroda, Vanita R., Saugstrup, Trine, Buse, John B., Donsmark, Morten, Zacho, Jeppe, Davies, Melanie J.

Volltext

Genetically Elevated C-Reactive Protein and Ischemic Vascular Disease von Zacho, Jeppe, Tybjærg-Hansen, Anne, Jensen, Jan Skov, Grande, Peer, Sillesen, Henrik, Nordestgaard, Børge G

Volltext

The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach von Nordestgaard, Børge G, Palmer, Tom M, Benn, Marianne, Zacho, Jeppe, Tybjaerg-Hansen, Anne, Davey Smith, George, Timpson, Nicholas J

Volltext

Exposure‐response analysis for evaluation of semaglutide dose levels in type 2 diabetes von Petri, Kristin C. C., Ingwersen, Steen H., Flint, Anne, Zacho, Jeppe, Overgaard, Rune V.

Volltext

C-Reactive Protein and the Risk of Cancer: A Mendelian Randomization Study von Allin, Kristine H., Nordestgaard, Børge G., Zacho, Jeppe, Tybjærg-Hansen, Anne, Bojesen, Stig E.

Volltext

Semaglutide s.c. Once-Weekly in Type 2 Diabetes: A Population Pharmacokinetic Analysis von Carlsson Petri, Kristin Cecilie, Ingwersen, Steen Hvass, Flint, Anne, Zacho, Jeppe, Overgaard, Rune Viig

Volltext

Insulin degludec/insulin aspart vs biphasic insulin aspart 30 twice daily in Japanese patients with type 2 diabetes: A randomized controlled trial von Onishi, Yukiko, Yamada, Kenichi, Zacho, Jeppe, Ekelund, Jan, Iwamoto, Yasuhiko

Volltext

Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53 221... von Lawlor, Debbie A., Harbord, Roger M., Tybjaerg‐Hansen, Anne, Palmer, Tom M., Zacho, Jeppe, Benn, Marianne, Timpson, Nicholas J., Davey Smith, George, Nordestgaard, Børge G.

Volltext

Safety and efficacy of once‐weekly semaglutide vs additional oral antidiabetic drugs in Japanese people with inadequately controlled type 2 diabetes: A randomized trial von Kaku, Kohei, Yamada, Yuichiro, Watada, Hirotaka, Abiko, Atsuko, Nishida, Tomoyuki, Zacho, Jeppe, Kiyosue, Arihiro

Volltext

Safety and efficacy of semaglutide once weekly vs sitagliptin once daily, both as monotherapy in Japanese people with type 2 diabetes von Seino, Yutaka, Terauchi, Yasuo, Osonoi, Takeshi, Yabe, Daisuke, Abe, Nobuyuki, Nishida, Tomoyuki, Zacho, Jeppe, Kaneko, Shizuka

Volltext

A 26-Week Randomized Controlled Trial of Semaglutide Once Daily Versus Liraglutide and Placebo in Patients With Type 2 Diabetes Suboptimally Controlled on Diet and Exercise With or... von Lingvay, Ildiko, Desouza, Cyrus V, Lalic, Katarina S, Rose, Ludger, Hansen, Thomas, Zacho, Jeppe, Pieber, Thomas R

Volltext

C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization von Timpson, N.J, Nordestgaard, B.G, Harbord, R.M, Zacho, J, Frayling, T.M, Tybjærg-Hansen, A, Smith, G. Davey

Volltext

SAT-201 Phase 3 randomised, placebo-controlled ESSENCE trial of semaglutide 2.4 mg in participants with non-cirrhotic non-alcoholic steatohepatitis: baseline characteristics, impac... von Newsome, Philip N., Bugianesi, Elisabetta, Ratziu, Vlad, Rinella, Mary E., Roden, Michael, Engebretsen, Kristiane A., Kliers, Iris, Østergaard, Laura, Vanni, Denise, Zacho, Jeppe, Sanyal, Arun J.

Volltext

Does Elevated C-Reactive Protein Increase Atrial Fibrillation Risk? von Marott, Sarah C.W., MD, Nordestgaard, Børge G., MD, DMSc, Zacho, Jeppe, MD, Friberg, Jens, MD, PhD, Jensen, Gorm B., MD, DMSc, Tybjærg-Hansen, Anne, MD, DMSc, Benn, Marianne, MD, PhD

Volltext

C-reactive protein and all-cause mortality—the Copenhagen City Heart Study von Zacho, Jeppe, Tybjærg-Hansen, Anne, Nordestgaard, Børge G.

Volltext

Does Greater Adiposity Increase Blood Pressure and Hypertension Risk?: Mendelian Randomization Using the FTO/MC4R Genotype von Timpson, Nicholas J, Harbord, Roger, Smith, George Davey, Zacho, Jeppe, Tybjærg-Hansen, Anne, Nordestgaard, Børge G

Volltext

Achieving glycaemic control without weight gain, hypoglycaemia, or gastrointestinal adverse events in type 2 diabetes in the SUSTAIN clinical trial programme von DeVries, J. Hans, Desouza, Cyrus, Bellary, Srikanth, Unger, Jeffrey, Hansen, Oluf K. H., Zacho, Jeppe, Woo, Vincent

Volltext

A Randomized Trial Investigating the Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Semaglutide Once-Weekly in Healthy Male Japanese and Caucasian Subjects von Ikushima, Ippei, Jensen, Lene, Flint, Anne, Nishida, Tomoyuki, Zacho, Jeppe, Irie, Shin

Volltext

Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials von Holmes, Michael V, DLSHTM, Newcombe, Paul, PhD, Hubacek, Jaroslav A, PhD, Sofat, Reecha, PhD, Ricketts, Sally L, PhD, Cooper, Jackie, MSc, Breteler, Monique MB, Prof, Bautista, Leonelo E, DrPH, Sharma, Pankaj, MD, Whittaker, John C, Prof, Smeeth, Liam, Prof, Fowkes, F Gerald R, Prof, Algra, Ale, Prof, Shmeleva, Veronika, MD, Szolnoki, Zoltan, PhD, Roest, Mark, PhD, Linnebank, Michael, MD, Zacho, Jeppe, MD, Nalls, Michael A, PhD, Singleton, Andrew B, PhD, Ferrucci, Luigi, MD, Hardy, John, Prof, Worrall, Bradford B, MD, Rich, Stephen S, Prof, Matarin, Mar, PhD, Norman, Paul E, FRACS, Flicker, Leon, FRACP, Almeida, Osvaldo P, Prof, van Bockxmeer, Frank M, Prof, Shimokata, Hiroshi, Prof, Khaw, Kay-Tee, Prof, Wareham, Nicholas J, Prof, Bobak, Martin, Prof, Sterne, Jonathan AC, Prof, Smith, George Davey, Prof, Talmud, Philippa J, Prof, van Duijn, Cornelia, Prof, Humphries, Steve E, Prof, Price, Jackie F, FFPH, Ebrahim, Shah, Prof, Lawlor, Debbie A, Prof, Hankey, Graeme J, FRACP, Meschia, James F, Prof, Sandhu, Manjinder S, PhD, Hingorani, Aroon D, Prof, Casas, Juan P, Dr

Volltext

Increased Baseline C-Reactive Protein Concentrations Are Associated with Increased Risk of Infections: Results from 2 Large Danish Population Cohorts von Zacho, Jeppe, Benfield, Thomas, Tybjærg-Hansen, Anne, Nordestgaard, Børge G

Volltext