Molecular Mechanisms of Treatment Resistance in Glioblastoma von Ou, Alexander, Yung, W. K. Alfred, Majd, Nazanin

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PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis von Yang, Weiwei, Xia, Yan, Hawke, David, Li, Xinjian, Liang, Ji, Xing, Dongming, Aldape, Kenneth, Hunter, Tony, Alfred Yung, W.K., Lu, Zhimin

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Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation von Noureen, Nighat, Wu, Shaofang, Lv, Yingli, Yang, Juechen, Alfred Yung, W. K., Gelfond, Jonathan, Wang, Xiaojing, Koul, Dimpy, Ludlow, Andrew, Zheng, Siyuan

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Role of AKT signaling in DNA repair and clinical response to cancer therapy von Liu, Qun, Turner, Kristen M, Alfred Yung, W K, Chen, Kexin, Zhang, Wei

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Phase 1 lead‐in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma von Maraka, Stefania, Groves, Morris D., Mammoser, Aaron G., Melguizo‐Gavilanes, Isaac, Conrad, Charles A., Tremont‐Lukats, Ivo W., Loghin, Monica E., O’Brien, Barbara J., Puduvalli, Vinay K., Sulman, Erik P., Hess, Kenneth R., Aldape, Kenneth D., Gilbert, Mark R., de Groot, John F., Alfred Yung, W.K., Penas‐Prado, Marta

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Genetic, epigenetic, and molecular landscapes of multifocal and multicentric glioblastoma von Liu, Qun, Liu, Yuexin, Li, Wenliang, Wang, Xiaoguang, Sawaya, Raymond, Lang, Frederick F., Yung, W. K. Alfred, Chen, Kexin, Fuller, Gregory N., Zhang, Wei

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Current clinical development of PI3K pathway inhibitors in glioblastoma von Wen, Patrick Y, Lee, Eudocia Q, Reardon, David A, Ligon, Keith L, Alfred Yung, W K

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Progression-free survival: an important end point in evaluating therapy for recurrent high-grade gliomas von Lamborn, Kathleen R, Yung, W K Alfred, Chang, Susan M, Wen, Patrick Y, Cloughesy, Timothy F, DeAngelis, Lisa M, Robins, H Ian, Lieberman, Frank S, Fine, Howard A, Fink, Karen L, Junck, Larry, Abrey, Lauren, Gilbert, Mark R, Mehta, Minesh, Kuhn, John G, Aldape, Kenneth D, Hibberts, Janelle, Peterson, Pamela M, Prados, Michael D

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Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma von Lang, Frederick F, Conrad, Charles, Gomez-Manzano, Candelaria, Yung, W K Alfred, Sawaya, Raymond, Weinberg, Jeffrey S, Prabhu, Sujit S, Rao, Ganesh, Fuller, Gregory N, Aldape, Kenneth D, Gumin, Joy, Vence, Luis M, Wistuba, Ignacio, Rodriguez-Canales, Jaime, Villalobos, Pamela A, Dirven, Clemens M F, Tejada, Sonia, Valle, Ricardo D, Alonso, Marta M, Ewald, Brett, Peterkin, Joanna J, Tufaro, Frank, Fueyo, Juan

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Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma von Friedman, Henry S, Prados, Michael D, Wen, Patrick Y, Mikkelsen, Tom, Schiff, David, Abrey, Lauren E, Yung, W K Alfred, Paleologos, Nina, Nicholas, Martin K, Jensen, Randy, Vredenburgh, James, Huang, Jane, Zheng, Maoxia, Cloughesy, Timothy

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Induction of cell-cycle arrest and apoptosis in glioblastoma stem-like cells by WP1193, a novel small molecule inhibitor of the JAK2/STAT3 pathway von Sai, Ke, Wang, Shuzhen, Balasubramaniyan, Veerakumar, Conrad, Charles, Lang, Frederick F., Aldape, Kenneth, Szymanski, Slawomir, Fokt, Izabela, Dasgupta, Atreyi, Madden, Timothy, Guan, Su, Chen, Zhongping, Alfred Yung, W. K., Priebe, Waldemar, Colman, Howard

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Phase I trial of aflibercept (VEGF trap) with radiation therapy and concomitant and adjuvant temozolomide in patients with high-grade gliomas von Nayak, Lakshmi, de Groot, John, Wefel, Jeffrey S., Cloughesy, Timothy F., Lieberman, Frank, Chang, Susan M., Omuro, Antonio, Drappatz, Jan, Batchelor, Tracy T., DeAngelis, Lisa M., Gilbert, Mark R., Aldape, Kenneth D., Yung, Alfred W. K., Fisher, Joy, Ye, Xiaobu, Chen, Alice, Grossman, Stuart, Prados, Michael, Wen, Patrick Y.

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Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers von Desai, Shruti, Ding, Minming, Wang, Bin, Lu, Zhimin, Zhao, Qi, Shaw, Kenna, Yung, W K Alfred, Weinstein, John N, Tan, Ming, Yao, Jun

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EGFR Amplification Induces Increased DNA Damage Response and Renders Selective Sensitivity to Talazoparib (PARP Inhibitor) in Glioblastoma von Wu, Shaofang, Gao, Feng, Zheng, Siyuan, Zhang, Chen, Martinez-Ledesma, Emmanuel, Ezhilarasan, Ravesanker, Ding, Jie, Li, Xiaolong, Feng, Ningping, Multani, Asha, Sulman, Erik P., Verhaak, Roel G., de Groot, John F., Heffernan, Tim P., Yung, W. K. Alfred, Koul, Dimpy

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Adaptive Global Innovative Learning Environment for Glioblastoma: GBM AGILE von Alexander, Brian M, Ba, Sujuan, Berger, Mitchel S, Berry, Donald A, Cavenee, Webster K, Chang, Susan M, Cloughesy, Timothy F, Jiang, Tao, Khasraw, Mustafa, Li, Wenbin, Mittman, Robert, Poste, George H, Wen, Patrick Y, Yung, W K Alfred, Barker, Anna D

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Antitumor Activity of NVP-BKM120―A Selective Pan Class I PI3 Kinase Inhibitor Showed Differential Forms of Cell Death Based on p53 Status of Glioma Cells von KOUL, Dimpy, JUN FU, GARCIA-ECHEVRRIA, Carlos, MAIRA, Sauveur-Michel, ALFRED YUNG, W. K, RUIJUN SHEN, LAFORTUNE, Tiffany A, SHUZHEN WANG, NINGYI TIAO, KIM, Yong-Wan, LIU, Juinn-Lin, RAMNARIAN, Deepti, YING YUAN

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Phase I study of AEE788, a novel multitarget inhibitor of ErbB- and VEGF-receptor-family tyrosine kinases, in recurrent glioblastoma patients von Reardon, David A., Conrad, Charles A., Cloughesy, Timothy, Prados, Michael D., Friedman, Henry S., Aldape, Kenneth D., Mischel, Paul, Xia, Jane, DiLea, Clifford, Huang, Jerry, Mietlowski, William, Dugan, Margaret, Chen, Wei, Yung, W. K. Alfred

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Tie2-FGFR1 Interaction Induces Adaptive PI3K Inhibitor Resistance by Upregulating Aurora A/PLK1/CDK1 Signaling in Glioblastoma von Li, Xiaolong, Martinez-Ledesma, Emmanuel, Zhang, Chen, Gao, Feng, Zheng, Siyuan, Ding, Jie, Wu, Shaofang, Nguyen, Nghi, Clifford, Stephan C, Wen, Patrick Y, Ligon, Keith L, Yung, W K Alfred, Koul, Dimpy

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The Promise of Poly(ADP-Ribose) Polymerase (PARP) Inhibitors in Gliomas von Majd, Nazanin, Yap, Timothy A, Yung, W K Alfred, de Groot, John

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Knockdown of GluR1 expression by RNA interference inhibits glioma proliferation von de Groot, John F., Piao, Yuji, Lu, Li, Fuller, Gregory N., Yung, W. K. Alfred

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