The Expression and Activation of the NF-κB Pathway Correlate with Methotrexate Resistance and Cell Proliferation in Acute Lymphoblastic Leukemia von Canevarolo, Rafael Renatino, Cury, Nathalia Moreno, Yunes, José Andrés

Volltext

IGFBP7 Fuels the Glycolytic Metabolism in B-Cell Precursor Acute Lymphoblastic Leukemia by Sustaining Activation of the IGF1R-Akt-GLUT1 Axis von Artico, Leonardo Luís, Ruas, Juliana Silveira, Teixeira Júnior, José Ricardo, Migita, Natacha Azussa, Seguchi, Gustavo, Shi, Xinghua, Brandalise, Silvia Regina, Castilho, Roger Frigério, Yunes, José Andrés

Volltext

Deleterious and Oncogenic Mutations in the IL7RA von Campos, Lívia Weijenborg, Pissinato, Leonardo Granato, Yunes, José Andrés

Volltext

Test trial of spike‐in immunoglobulin heavy‐chain (IGH) controls for next generation sequencing quantification of minimal residual disease in acute lymphoblastic leukaemia von Giusti, Guilherme Navarro Nilo, Jotta, Patrícia Yoshioka, Lopes, Caroline de Oliveira, Ganazza, Monica Aparecida, Azevedo, Amilcar Cardoso, Brandalise, Sílvia Regina, Meidanis, João, Yunes, José Andrés

Volltext

Glutathione levels are associated with methotrexate resistance in acute lymphoblastic leukemia cell lines von Canevarolo, Rafael Renatino, Melo, Carolina Pereira de Souza, Cury, Nathalia Moreno, Artico, Leonardo Luiz, Corrêa, Juliana Ronchi, Tonhasca Lau, Yanca, Mariano, Samara Sousa, Sudalagunta, Praneeth Reddy, Brandalise, Silvia Regina, Zeri, Ana Carolina de Mattos, Yunes, José Andrés

Volltext

Occurrence of Neuroblastoma among TP53 p.R337H Carriers von Seidinger, Ana Luiza, Fortes, Fernanda Paschoal, Mastellaro, Maria José, Cardinalli, Izilda Aparecida, Zambaldi, Lilian Girotto, Aguiar, Simone Santos, Yunes, José Andrés

Volltext

SB225002 Induces Cell Death and Cell Cycle Arrest in Acute Lymphoblastic Leukemia Cells through the Activation of GLIPR1 von de Vasconcellos, Jaíra Ferreira, Laranjeira, Angelo Brunelli Albertoni, Leal, Paulo C, Bhasin, Manoj K, Zenatti, Priscila Pini, Nunes, Ricardo J, Yunes, Rosendo A, Nowill, Alexandre E, Libermann, Towia A, Zerbini, Luiz Fernando, Yunes, José Andrés

Volltext

Low Bioavailability and High Immunogenicity of a New Brand of E. coli l-Asparaginase with Active Host Contaminating Proteins von Zenatti, Priscila Pini, Migita, Natacha Azussa, Cury, Nathália Moreno, Mendes-Silva, Rosângela Aparecida, Gozzo, Fabio Cesar, de Campos-Lima, Pedro Otavio, Yunes, José Andrés, Brandalise, Silvia Regina

Volltext

CLINICAL, DEMOGRAPHIC, ANATOMOPATHOLOGICAL, AND MOLECULAR FINDINGS IN PATIENTS WITH MEDULLOBLASTOMA TREATED IN A SINGLE HEALTH FACILITY von Hoffmann, Iva Loureiro, Cardinalli, Izilda Aparecida, Yunes, José Andrés, Seidinger, Ana Luiza, Pereira, Ricardo Mendes

Volltext

Vidjil add‐on for MRD quantification of samples processed using the EuroClonality‐NGS protocol von Giusti, Guilherme Navarro Nilo, Ribeiro, Antonio Vítor, Jotta, Patrícia Yoshioka, Thonier, Florian, Yunes, José Andrés, Meidanis, João

Volltext

Plasma Hsp90 Level as a Marker of Early Acute Lymphoblastic Leukemia Engraftment and Progression in Mice von Milani, Mateus, Laranjeira, Angelo Brunelli Albertoni, de Vasconcellos, Jaíra Ferreira, Brandalise, Silvia Regina, Nowill, Alexandre Eduardo, Yunes, José Andrés

Volltext

CAISMOV24, a new human low-grade serous ovarian carcinoma cell line von da Silva, Rodrigo Fernandes, Cardozo, Daniela Maira, Rodrigues, Gisele Olinto Libanio, Souza-Araújo, Caroline Natânia de, Migita, Natacha Azussa, Andrade, Liliana Aparecida Lucci de Angelo, Derchain, Sophie, Yunes, José Andrés, Guimarães, Fernando

Volltext

Structural Basis of Colchicine-Site targeting Acylhydrazones active against Multidrug-Resistant Acute Lymphoblastic Leukemia von Cury, Nathália Moreno, Mühlethaler, Tobias, Laranjeira, Angelo Brunelli Albertoni, Canevarolo, Rafael Renatino, Zenatti, Priscila Pini, Lucena-Agell, Daniel, Barasoain, Isabel, Song, Chunhua, Sun, Dongxiao, Dovat, Sinisa, Yunes, Rosendo Augusto, Prota, Andrea Enrico, Steinmetz, Michel Olivier, Díaz, José Fernando, Yunes, José Andrés

Volltext

Synthesis and evaluation of 2-carboxy indole derivatives as potent and selective anti-leukemic agents von Cury, Nathália Moreno, Capitão, Rebeca Monique, Almeida, Renan do Canto Borges de, Artico, Leonardo Luís, Corrêa, Juliana Ronchi, Simão dos Santos, Eric Francisco, Yunes, José Andrés, Correia, Carlos Roque Duarte

Volltext

Structural and kinetic characterization of a maize aldose reductase von de Sousa, Sylvia Morais, Rosselli, Luciana K., Kiyota, Eduardo, da Silva, Julio César, Souza, Gustavo H.M.F., Peroni, Luis Antonio, Stach-Machado, Dagmar R., Eberlin, Marcos N., Souza, Anete P., Koch, Karen E., Arruda, Paulo, Torriani, Íris L., Yunes, José Andrés

Volltext

Oncogenic basic amino acid insertions at the extracellular juxtamembrane region of IL7RA cause receptor hypersensitivity von Weijenborg Campos, Livia, Pini Zenatti, Priscila, Granato Pissinato, Leonardo, Libanio Rodrigues, Gisele O., Artico, Leonardo Luís, Rafael Guimarães, Thais, Fröhlich Archangelo, Leticia, Martínez, Leandro, Brooks, Andrew J., Yunes, José Andrés

Volltext

A comparative structural analysis reveals distinctive features of co-factor binding and substrate specificity in plant aldo-keto reductases von Giuseppe, Priscila Oliveira de, Santos, Marcelo Leite dos, Sousa, Sylvia Morais de, Koch, Karen E., Yunes, José Andrés, Aparicio, Ricardo, Murakami, Mario Tyago

Volltext

Association of the highly prevalent TP53 R337H mutation with pediatric choroid plexus carcinoma and osteosarcoma in Southeast Brazil von Seidinger, Ana Luiza, Mastellaro, Maria José, Paschoal Fortes, Fernanda, Godoy Assumpção, Juliana, Aparecida Cardinalli, Izilda, Aparecida Ganazza, Mônica, Correa Ribeiro, Raul, Brandalise, Silvia Regina, dos Santos Aguiar, Simone, Yunes, José Andrés

Volltext

Physiologic IGFBP7 levels prolong IGF1R activation in acute lymphoblastic leukemia von Artico, Leonardo Luís, Laranjeira, Angelo Brunelli Albertoni, Campos, Livia Weijenborg, Corrêa, Juliana Ronchi, Zenatti, Priscila Pini, Carvalheira, José Barreto Campello, Brambilla, Sandra Regina, Nowill, Alexandre Eduardo, Brandalise, Silvia Regina, Yunes, José Andrés

Volltext

PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemia von Silveira, André Bortolini, Laranjeira, Angelo Brunelli Albertoni, Rodrigues, Gisele Olinto Libanio, Leal, Paulo César, Caetano Cardoso, Bruno António, Barata, João, Yunes, Rosendo Augusto, Zanchin, Nilson Ivo Tonin, Brandalise, Sílvia Regina, Yunes, José Andrés

Volltext