Activation of the thrombopoietin receptor by mutant calreticulin in CALR-mutant myeloproliferative neoplasms von Araki, Marito, Yang, Yinjie, Masubuchi, Nami, Hironaka, Yumi, Takei, Hiraku, Morishita, Soji, Mizukami, Yoshihisa, Kan, Shin, Shirane, Shuichi, Edahiro, Yoko, Sunami, Yoshitaka, Ohsaka, Akimichi, Komatsu, Norio

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Mutant calreticulin interacts with MPL in the secretion pathway for activation on the cell surface von Masubuchi, Nami, Araki, Marito, Yang, Yinjie, Hayashi, Erina, Imai, Misa, Edahiro, Yoko, Hironaka, Yumi, Mizukami, Yoshihisa, Kihara, Yoshihiko, Takei, Hiraku, Nudejima, Mai, Koike, Masato, Ohsaka, Akimichi, Komatsu, Norio

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Homomultimerization of mutant calreticulin is a prerequisite for MPL binding and activation von Araki, Marito, Yang, Yinjie, Imai, Misa, Mizukami, Yoshihisa, Kihara, Yoshihiko, Sunami, Yoshitaka, Masubuchi, Nami, Edahiro, Yoko, Hironaka, Yumi, Osaga, Satoshi, Ohsaka, Akimichi, Komatsu, Norio

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Histone Acetyltransferase p300/CREB-binding Protein-associated Factor (PCAF) Is Required for All-trans-retinoic Acid-induced Granulocytic Differentiation in Leukemia Cells von Sunami, Yoshitaka, Araki, Marito, Kan, Shin, Ito, Akihiro, Hironaka, Yumi, Imai, Misa, Morishita, Soji, Ohsaka, Akimichi, Komatsu, Norio

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JAK2, CALR, and MPL mutation spectrum in Japanese patients with myeloproliferative neoplasms von Shirane, Shuichi, Araki, Marito, Morishita, Soji, Edahiro, Yoko, Takei, Hiraku, Yoo, Yongjin, Choi, Murim, Sunami, Yoshitaka, Hironaka, Yumi, Noguchi, Masaaki, Koike, Michiaki, Noda, Naohiro, Ohsaka, Akimichi, Komatsu, Norio

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Inhibition of the NAD-dependent protein deacetylase SIRT2 induces granulocytic differentiation in human leukemia cells von Sunami, Yoshitaka, Araki, Marito, Hironaka, Yumi, Morishita, Soji, Kobayashi, Masaki, Liew, Ei Leen, Edahiro, Yoko, Tsutsui, Miyuki, Ohsaka, Akimichi, Komatsu, Norio

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Melting curve analysis after T allele enrichment (MelcaTle) as a highly sensitive and reliable method for detecting the JAK2V617F mutation von Morishita, Soji, Takahashi, Kochi, Araki, Marito, Hironaka, Yumi, Sunami, Yoshitaka, Edahiro, Yoko, Tsutsui, Miyuki, Ohsaka, Akimichi, Tsuneda, Satoshi, Komatsu, Norio

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Detection of MPLW515L/K mutations and determination of allele frequencies with a single-tube PCR assay von Takei, Hiraku, Morishita, Soji, Araki, Marito, Edahiro, Yoko, Sunami, Yoshitaka, Hironaka, Yumi, Noda, Naohiro, Sekiguchi, Yuji, Tsuneda, Satoshi, Ohsaka, Akimichi, Komatsu, Norio

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JAK2V617F mutation status and allele burden in classical Ph-negative myeloproliferative neoplasms in Japan von Edahiro, Yoko, Morishita, Soji, Takahashi, Kochi, Hironaka, Yumi, Yahata, Yuriko, Sunami, Yoshitaka, Shirane, Shuichi, Tsutsui, Miyuki, Noguchi, Masaaki, Koike, Michiaki, Imai, Kiyotoshi, Kirito, Keita, Noda, Naohiro, Sekiguchi, Yuji, Tsuneda, Satoshi, Ohsaka, Akimichi, Araki, Marito, Komatsu, Norio

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Consequences of the JAK2V617F allele burden for the prediction of transformation into myelofibrosis from polycythemia vera and essential thrombocythemia von Shirane, Shuichi, Araki, Marito, Morishita, Soji, Edahiro, Yoko, Sunami, Yoshitaka, Hironaka, Yumi, Noguchi, Masaaki, Koike, Michiaki, Sato, Eriko, Ohsaka, Akimichi, Komatsu, Norio

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Identification of AIM2 as a downstream target of JAK2V617F von Liew, Ei Leen, Araki, Marito, Hironaka, Yumi, Mori, Seiichi, Tan, Tuan Zea, Morishita, Soji, Edahiro, Yoko, Ohsaka, Akimichi, Komatsu, Norio

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Mechanisms Governing the Accumulation of Mutant Calreticulin von Yoshihiko Kihara, Marito Araki, Yinjie Yang, Misa Imai, Nami Masubuchi, Yoshihisa Mizukami, Yumi Hironaka, Soji Morishita, Akimichi Ohsaka, Norio Komatsu

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Gene Expression Profiles During All-Trans Retinoic Acid (ATRA)-Induced Differentiation in Leukemia Cells von Nami Masubuchi, Yoshitaka Sunami, Marito Araki, Kaoru Mogushi, Yumi Hironaka, Misa Imai, Soji Morishita, Akimichi Ohsaka, Norio Komatsu

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Establishment of a Live-Imaging System Monitoring the Oncogenic Mutant Calreticulin in Human Megakaryocytic UT-7/TPO Cells von Yoshihisa Mizukami, Marito Araki, Erina Hayashi, Yinjie Yang, Yumi Hironaka, Yoshihiko Kihara, Nami Masubuchi, Misa Imai, Akimichi Ohsaka, Norio Komatsu

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Engagement of Mutant Molecular Chaperone and Cytokine Receptor in the Secretary is Required for the Cellular Transformation von Nami Masubuchi, Marito Araki, Erina Hayashi, Yinjie Yang, Misa Imai, Yoshihiko Kihara, Yoshihisa Mizukami, Yumi Hironaka, Hiraku Takei, Yoko Edahiro, Akimichi Ohsaka, Norio Komatsu

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Correction: Inhibition of the NAD-Dependent Protein Deacetylase SIRT2 Induces Granulocytic Differentiation in Human Leukemia Cells von Sunami, Yoshitaka, Araki, Marito, Hironaka, Yumi, Morishita, Soji, Kobayashi, Masaki, Liew, Ei Leen, Edahiro, Yoko, Tsutsui, Miyuki, Ohsaka, Akimichi, Komatsu, Norio

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Boarding the Secretory Pathway Is Required for the Oncogenic Capacity of Mutant Calreticulin von Nami Masubuchi, Marito Araki, Erina Hayashi, Yinjie Yang, Misa Imai, Yoshihiko Kihara, Yoshihisa Mizukami, Yumi Hironaka, Hiraku Takei, Yoko Edahiro, Akimichi Ohsaka, Norio Komatsu

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Thrombopoietin-Independent Megakaryopoiesis in iPS-Derived Hematopoietic Progenitor Cells Harboring Calreticulin Mutation von Marito Araki, Hiraku Takei, Yinjie Yang, Yoshihisa Mizukami, Nami Masubuchi, Erina Hayashi, Misa Imai, Yumi Hironaka, Soji Morishita, Akimichi Ohsaka, Norio Komatsu

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Activation of the Thrombopoietin Receptor by Mutant Calreticulin in CALR-Mutant Myeloproliferative Neoplasms von Marito Araki, Yinjie Yang, Nami Masubuchi, Yumi Hironaka, Hiraku Takei, Soji Morishita, Yoshihisa Mizukami, Akimichi Ohsaka, Norio Komatsu

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Activation of AP-1 By JAK2V617F through Induction and Stabilization of c-FOS von Edahiro, Yoko, Araki, Marito, Hironaka, Yumi, Yang, Yinjie, Morishita, Soji, Sunami, Yoshitaka, Ohsaka, Akimichi, Komatsu, Norio

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