A selective c-Fos/AP-1 inhibitor prevents cartilage destruction and subsequent osteophyte formation von Motomura, Hiraku, Seki, Shoji, Shiozawa, Shunichi, Aikawa, Yukihiko, Nogami, Makiko, Kimura, Tomoatsu

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Discovery of Nonpeptidic Small-Molecule AP-1 Inhibitors:  Lead Hopping Based on a Three-Dimensional Pharmacophore Model von Tsuchida, Keiichi, Chaki, Hisaaki, Takakura, Tadakazu, Kotsubo, Hironori, Tanaka, Tadashi, Aikawa, Yukihiko, Shiozawa, Shunichi, Hirono, Shuichi

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Treatment of arthritis with a selective inhibitor of c-Fos/activator protein-1 von Aikawa, Yukihiko, Morimoto, Kimiko, Narita, Hirokazu, Hashiramoto, Akira, Hirono, Shuichi, Yamamoto, Tetsuya, Shiozawa, Shunichi, Chaki, Hisaaki

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A selective inhibition of c-Fos/activator protein-1 as a potential therapeutic target for intervertebral disc degeneration and associated pain von Makino, Hiroto, Seki, Shoji, Yahara, Yasuhito, Shiozawa, Shunichi, Aikawa, Yukihiko, Motomura, Hiraku, Nogami, Makiko, Watanabe, Kenta, Sainoh, Takeshi, Ito, Hisakatsu, Tsumaki, Noriyuki, Kawaguchi, Yoshiharu, Yamazaki, Mitsuaki, Kimura, Tomoatsu

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Competitive PCR quantification of pro- and anti-inflammatory cytokine mRNA in the central nervous system during autoimmune encephalomyelitis von Tanuma, Naoyuki, Kojima, Takashi, Shin, Taekyun, Aikawa, Yukihiko, Kohji, Toshihiko, Ishihara, Yoshihiro, Matsumoto, Yoh

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Myosin-induced autoimmune polymyositis in the rat von Kojima, Takashi, Tanuma, Naoyuki, Aikawa, Yukihiko, Shin, Taekyun, Sasaki, Atsusi, Matsumoto, Yoh

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Role of natural killer cells and TCRγ δ T cells in acute autoimmune encephalomyelitis von Matsumoto, Yoh, Kohyama, Kuniko, Aikawa, Yukihiko, Shin, Taekyun, Kawazoe, Yoko, Suzuki, Yoko, Tanuma, Naoyuki

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Design, Synthesis, and Biological Evaluation of New Cyclic Disulfide Decapeptides That Inhibit the Binding of AP-1 to DNA von Tsuchida, Keiichi, Chaki, Hisaaki, Takakura, Tadakazu, Yokotani, Junichi, Aikawa, Yukihiko, Shiozawa, Shunichi, Gouda, Hiroaki, Hirono, Shuichi

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método e composição farmacêutica para o tratamento de doenças autoimunes von Yukihiko Aikawa, Shunichi Shiozawa

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uso de um derivado de benzofenona e de um ou mais agentes imunossupressores em combinação, composição farmacéutica para o tratamento de doenças autoimunes, e, kit von Yukihiko Aikawa, Shunichi Shiozawa

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Tumor necrosis factor stimulates gelatinase and collagenase production by granulation tissue in culture von Nakagawa, Hideo, Kitagawa, Hisashi, Aikawa, Yukihiko

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Method of utilization of combination of benzophenone derivative or salt thereof and immunosuppressing agent, and pharmaceutical composition comprising these components von AIKAWA YUKIHIKO, SHIOZAWA SHUNICHI

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USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNFalpha INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR von SHIOZAWA, SHUNICHI, AIKAWA, YUKIHIKO

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USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNFalpha INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR von AIKAWA YUKIHIKO, SHIOZAWA SHUNICHI

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USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNFALFA INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR von SHIOZAWA, SHUNICHI, AIKAWA, YUKIHIKO

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ANVENDELSE AF ET BENZOPHENONDERIVAT ELLER ET SALT DERAF I KOMBINATION MED EN TNFalfa-INHIBITOR OG FARMACEUTISK SAMMENSÆTNING INDEHOLDENDE DERIVATET ELLER SALTET DERAF OG INHIBITORE... von SHIOZAWA, SHUNICHI, AIKAWA, YUKIHIKO

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USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNFALPHA INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR von YUKIHIKO AIKAWA, SHUNICHI SHIOZAWA

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USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNFalpha INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR von SHIOZAWA, SHUNICHI, AIKAWA, YUKIHIKO

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METHOD USING BENZOPHENONE DERIVATIVE OR SALT THEREOF AND IMMUNOSUPPRESSIVE AGENT IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THESE von AIKAWA YUKIHIKO, SHIOZAWA SHUNICHI

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A new anti-rheumatic drug, T-614, effectively suppresses the development of autoimmune encephalomyelitis von Aikawa, Yukihiko, Tanuma, Naoyuki, Shin, Taekyun, Makino, Shinji, Tanaka, Keiichi, Matsumoto, Yoh

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