Clonal evolution leading to ibrutinib resistance in chronic lymphocytic leukemia von Ahn, Inhye E., Underbayev, Chingiz, Albitar, Adam, Herman, Sarah E.M., Tian, Xin, Maric, Irina, Arthur, Diane C., Wake, Laura, Pittaluga, Stefania, Yuan, Constance M., Stetler-Stevenson, Maryalice, Soto, Susan, Valdez, Janet, Nierman, Pia, Lotter, Jennifer, Xi, Liqiang, Raffeld, Mark, Farooqui, Mohammed, Albitar, Maher, Wiestner, Adrian

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Anti-CD22–chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia von Haso, Waleed, Lee, Daniel W., Shah, Nirali N., Stetler-Stevenson, Maryalice, Yuan, Constance M., Pastan, Ira H., Dimitrov, Dimiter S., Morgan, Richard A., FitzGerald, David J., Barrett, David M., Wayne, Alan S., Mackall, Crystal L., Orentas, Rimas J.

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Depth and durability of response to ibrutinib in CLL: 5-year follow-up of a phase 2 study von Ahn, Inhye E., Farooqui, Mohammed Z.H., Tian, Xin, Valdez, Janet, Sun, Clare, Soto, Susan, Lotter, Jennifer, Housel, Stephanie, Stetler-Stevenson, Maryalice, Yuan, Constance M., Maric, Irina, Calvo, Katherine R., Nierman, Pia, Hughes, Thomas E., Saba, Nakhle S., Marti, Gerald E., Pittaluga, Stefania, Herman, Sarah E.M., Niemann, Carsten U., Pedersen, Lone B., Geisler, Christian H., Childs, Richard, Aue, Georg, Wiestner, Adrian

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Sequential loss of tumor surface antigens following chimeric antigen receptor T-cell therapies in diffuse large B-cell lymphoma von Shalabi, Haneen, Kraft, Ira L, Wang, Hao-Wei, Yuan, Constance M, Yates, Bonnie, Delbrook, Cindy, Zimbelman, Julie D, Giller, Roger, Stetler-Stevenson, Maryalice, Jaffe, Elaine S, Lee, Daniel W, Shern, Jack F, Fry, Terry J, Shah, Nirali N

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Preclinical Development of Bivalent Chimeric Antigen Receptors Targeting Both CD19 and CD22 von Qin, Haiying, Ramakrishna, Sneha, Nguyen, Sang, Fountaine, Thomas J., Ponduri, Anusha, Stetler-Stevenson, Maryalice, Yuan, Constance M., Haso, Waleed, Shern, Jack F., Shah, Nirali N., Fry, Terry J.

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Characterization of CD22 expression in acute lymphoblastic leukemia von Shah, Nirali N., Stevenson, Maryalice Stetler, Yuan, Constance M., Richards, Kelly, Delbrook, Cindy, Kreitman, Robert J., Pastan, Ira, Wayne, Alan S.

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Daratumumab induces cell-mediated cytotoxicity of primary effusion lymphoma and is active against refractory disease von Shrestha, Prabha, Astter, Yana, Davis, David A., Zhou, Ting, Yuan, Constance M., Ramaswami, Ramya, Wang, Hao-Wei, Lurain, Kathryn, Yarchoan, Robert

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Long-Term Follow-Up of CD19-CAR T-Cell Therapy in Children and Young Adults With B-ALL von Shah, Nirali N., Lee, Daniel W., Yates, Bonnie, Yuan, Constance M., Shalabi, Haneen, Martin, Staci, Wolters, Pamela L., Steinberg, Seth M., Baker, Eva H., Delbrook, Cindy P., Stetler-Stevenson, Maryalice, Fry, Terry J., Stroncek, David F., Mackall, Crystal L.

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CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy von Fry, Terry J, Shah, Nirali N, Orentas, Rimas J, Stetler-Stevenson, Maryalice, Yuan, Constance M, Ramakrishna, Sneha, Wolters, Pamela, Martin, Staci, Delbrook, Cindy, Yates, Bonnie, Shalabi, Haneen, Fountaine, Thomas J, Shern, Jack F, Majzner, Robbie G, Stroncek, David F, Sabatino, Marianna, Feng, Yang, Dimitrov, Dimiter S, Zhang, Ling, Nguyen, Sang, Qin, Haiying, Dropulic, Boro, Lee, Daniel W, Mackall, Crystal L

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CRLF2 -rearranged B-cell ALL with extramedullary lineage switch to AML following CD19-targeted therapy von Silbert, Sara K, Scanlon, Samantha, Wang, Hao-Wei, Yuan, Constance M, Doverte, Alyssa, Wellek, Jake, Patel, Nisha, Braylan, Raul, Ahlman, Mark, Turkbey, Evrim B, Bohling, Sandra D, Chisholm, Karen M, Oztek, Murat Alp, LaLoggia, Mike, Verma, Anupam, Shalabi, Haneen, Kovach, Alexandra E, Wood, Brent L, Lamble, Adam, Kirsch, Ilan, Leger, Kasey, Shah, Nirali N

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Lymphoma Remissions Caused by Anti-CD19 Chimeric Antigen Receptor T Cells Are Associated With High Serum Interleukin-15 Levels von Kochenderfer, James N, Somerville, Robert P T, Lu, Tangying, Shi, Victoria, Bot, Adrian, Rossi, John, Xue, Allen, Goff, Stephanie L, Yang, James C, Sherry, Richard M, Klebanoff, Christopher A, Kammula, Udai S, Sherman, Marika, Perez, Arianne, Yuan, Constance M, Feldman, Tatyana, Friedberg, Jonathan W, Roschewski, Mark J, Feldman, Steven A, McIntyre, Lori, Toomey, Mary Ann, Rosenberg, Steven A

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Blinatumomab Nonresponse and High-Disease Burden Are Associated With Inferior Outcomes After CD19-CAR for B-ALL von Myers, Regina M, Taraseviciute, Agne, Steinberg, Seth M, Lamble, Adam J, Sheppard, Jennifer, Yates, Bonnie, Kovach, Alexandra E, Wood, Brent, Borowitz, Michael J, Stetler-Stevenson, Maryalice, Yuan, Constance M, Pillai, Vinodh, Foley, Toni, Chung, Perry, Chen, Lee, Lee, Daniel W, Annesley, Colleen, DiNofia, Amanda, Grupp, Stephan A, John, Samuel, Bhojwani, Deepa, Brown, Patrick A, Laetsch, Theodore W, Gore, Lia, Gardner, Rebecca A, Rheingold, Susan R, Pulsipher, Michael A, Shah, Nirali N

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Modulation of Target Antigen Density Improves CAR T-cell Functionality and Persistence von Ramakrishna, Sneha, Highfill, Steven L, Walsh, Zachary, Nguyen, Sang M, Lei, Haiyan, Shern, Jack F, Qin, Haiying, Kraft, Ira L, Stetler-Stevenson, Maryalice, Yuan, Constance M, Hwang, Jennifer D, Feng, Yang, Zhu, Zhongyu, Dimitrov, Dimiter, Shah, Nirali N, Fry, Terry J

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Clinical and biological implications of target occupancy in CLL treated with the BTK inhibitor acalabrutinib von Sun, Clare, Nierman, Pia, Kendall, Ellen K., Cheung, Jean, Gulrajani, Michael, Herman, Sarah E.M., Pleyer, Christopher, Ahn, Inhye E., Stetler-Stevenson, Maryalice, Yuan, Constance M., Maric, Irina, Gaglione, Erika M., Harris, Hailey M., Pittaluga, Stefania, Wang, Min Hui, Patel, Priti, Farooqui, Mohammed Z.H., Izumi, Raquel, Hamdy, Ahmed, Covey, Todd, Wiestner, Adrian

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Randomized Phase II Study of First-Line Cladribine With Concurrent or Delayed Rituximab in Patients With Hairy Cell Leukemia von Chihara, Dai, Arons, Evgeny, Stetler-Stevenson, Maryalice, Yuan, Constance M., Wang, Hao-Wei, Zhou, Hong, Raffeld, Mark, Xi, Liqiang, Steinberg, Seth M., Feurtado, Julie, James, Lacey, Wilson, Wyndham, Braylan, Raul C., Calvo, Katherine R., Maric, Irina, Dulau-Florea, Alina, Kreitman, Robert J.

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Phase II Trial of Inotuzumab Ozogamicin in Children and Adolescents With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia: Children's Oncology Group Protocol AALL1621 von O'Brien, Maureen M, Ji, Lingyun, Shah, Nirali N, Rheingold, Susan R, Bhojwani, Deepa, Yuan, Constance M, Xu, Xinxin, Yi, Joanna S, Harris, Andrew C, Brown, Patrick A, Borowitz, Michael J, Militano, Olga, Kairalla, John, Devidas, Meenakshi, Raetz, Elizabeth A, Gore, Lia, Loh, Mignon L

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CD19/22 CAR T cells in children and young adults with B-ALL: phase 1 results and development of a novel bicistronic CAR von Shalabi, Haneen, Qin, Haiying, Su, Angela, Yates, Bonnie, Wolters, Pamela L., Steinberg, Seth M., Ligon, John A., Silbert, Sara, DéDé, Kniya, Benzaoui, Mehdi, Goldberg, Sophia, Achar, Sooraj, Schneider, Dina, Shahani, Shilpa A., Little, Lauren, Foley, Toni, Molina, John C., Panch, Sandhya, Mackall, Crystal L., Lee, Daniel W., Chien, Christopher D., Pouzolles, Marie, Ahlman, Mark, Yuan, Constance M., Wang, Hao-Wei, Wang, Yanyu, Inglefield, Jon, Toledo-Tamula, Mary Anne, Martin, Staci, Highfill, Steven L., Altan-Bonnet, Gregoire, Stroncek, David, Fry, Terry J., Taylor, Naomi, Shah, Nirali N.

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Disruption of in vivo Chronic Lymphocytic Leukemia Tumor-Microenvironment Interactions by Ibrutinib--Findings from an Investigator-Initiated Phase II Study von Niemann, Carsten U, Herman, Sarah E M, Maric, Irina, Gomez-Rodriguez, Julio, Biancotto, Angelique, Chang, Betty Y, Martyr, Sabrina, Stetler-Stevenson, Maryalice, Yuan, Constance M, Calvo, Katherine R, Braylan, Raul C, Valdez, Janet, Lee, Yuh Shan, Wong, Deanna H, Jones, Jade, Sun, Clare, Marti, Gerald E, Farooqui, Mohammed Z H, Wiestner, Adrian

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Direct in vivo evidence for increased proliferation of CLL cells in lymph nodes compared to bone marrow and peripheral blood von Herndon, T M, Chen, S-S, Saba, N S, Valdez, J, Emson, C, Gatmaitan, M, Tian, X, Hughes, T E, Sun, C, Arthur, D C, Stetler-Stevenson, M, Yuan, C M, Niemann, C U, Marti, G E, Aue, G, Soto, S, Farooqui, M Z H, Herman, S E M, Chiorazzi, N, Wiestner, A

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Serial evaluation of CD19 surface expression in pediatric B-cell malignancies following CD19-targeted therapy von Libert, Diane, Yuan, Constance M., Masih, Katherine E., Galera, Pallavi, Salem, Dalia, Shalabi, Haneen, Yates, Bonnie, Delbrook, Cindy, Shern, Jack F., Fry, Terry J., Khan, Javed, Stetler-Stevenson, Maryalice, Shah, Nirali N.

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