Developing Therapeutic Antibodies for Neurodegenerative Disease von Yu, Y. Joy, Watts, Ryan J.

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Discovery of Novel Blood-Brain Barrier Targets to Enhance Brain Uptake of Therapeutic Antibodies von Zuchero, Y. Joy Yu, Chen, Xiaocheng, Bien-Ly, Nga, Bumbaca, Daniela, Tong, Raymond K., Gao, Xiaoying, Zhang, Shuo, Hoyte, Kwame, Luk, Wilman, Huntley, Melanie A., Phu, Lilian, Tan, Christine, Kallop, Dara, Weimer, Robby M., Lu, Yanmei, Kirkpatrick, Donald S., Ernst, James A., Chih, Ben, Dennis, Mark S., Watts, Ryan J.

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Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants von Bien-Ly, Nga, Yu, Y Joy, Bumbaca, Daniela, Elstrott, Justin, Boswell, C Andrew, Zhang, Yin, Luk, Wilman, Lu, Yanmei, Dennis, Mark S, Weimer, Robby M, Chung, Inhee, Watts, Ryan J

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Effector-attenuating Substitutions That Maintain Antibody Stability and Reduce Toxicity in Mice von Lo, Megan, Kim, Hok Seon, Tong, Raymond K., Bainbridge, Travis W., Vernes, Jean-Michel, Zhang, Yin, Lin, Yuwen Linda, Chung, Shan, Dennis, Mark S., Zuchero, Y. Joy Yu, Watts, Ryan J., Couch, Jessica A., Meng, Y. Gloria, Atwal, Jasvinder K., Brezski, Randall J., Spiess, Christoph, Ernst, James A.

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CD98hc is a target for brain delivery of biotherapeutics von Chew, Kylie S., Wells, Robert C., Moshkforoush, Arash, Chan, Darren, Lechtenberg, Kendra J., Tran, Hai L., Chow, Johann, Kim, Do Jin, Robles-Colmenares, Yaneth, Srivastava, Devendra B., Tong, Raymond K., Tong, Mabel, Xa, Kaitlin, Yang, Alexander, Zhou, Yinhan, Akkapeddi, Padma, Annamalai, Lakshman, Bajc, Kaja, Blanchette, Marie, Cherf, Gerald Maxwell, Earr, Timothy K., Gill, Audrey, Huynh, David, Joy, David, Knight, Kristen N., Lac, Diana, Leung, Amy Wing-Sze, Lexa, Katrina W., Liau, Nicholas P. D., Becerra, Isabel, Malfavon, Mario, McInnes, Joseph, Nguyen, Hoang N., Lozano, Edwin I., Pizzo, Michelle E., Roche, Elysia, Sacayon, Patricia, Calvert, Meredith E. K., Daneman, Richard, Dennis, Mark S., Duque, Joseph, Gadkar, Kapil, Lewcock, Joseph W., Mahon, Cathal S., Meisner, René, Solanoy, Hilda, Thorne, Robert G., Watts, Ryan J., Zuchero, Y. Joy Yu, Kariolis, Mihalis S.

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Nucleus accumbens dopamine differentially mediates the formation and maintenance of monogamous pair bonds von Aragona, Brandon J, Liu, Yan, Yu, Y Joy, Curtis, J Thomas, Detwiler, Jacqueline M, Insel, Thomas R, Wang, Zuoxin

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Fast Modulation of μ-Opioid Receptor (MOR) Recycling Is Mediated by Receptor Agonists von Roman-Vendrell, Cristina, Yu, Y. Joy, Yudowski, Guillermo Ariel

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Stereocontrolled Disruption of the Ugi Reaction toward the Production of Chiral Piperazinones: Substrate Scope and Process Development von Zaretsky, Serge, Adachi, Shinya, Rotstein, Benjamin H, Hickey, Jennifer L, Scully, Conor C. G, St. Denis, Jeffrey D, Courtemanche, Rebecca, Yu, Joy C. Y, Chung, Benjamin K. W, Yudin, Andrei K

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Author Correction: CD98hc is a target for brain delivery of biotherapeutics von Chew, Kylie S., Wells, Robert C., Moshkforoush, Arash, Chan, Darren, Lechtenberg, Kendra J., Tran, Hai L., Chow, Johann, Kim, Do Jin, Robles-Colmenares, Yaneth, Srivastava, Devendra B., Tong, Raymond K., Tong, Mabel, Xa, Kaitlin, Yang, Alexander, Zhou, Yinhan, Akkapeddi, Padma, Annamalai, Lakshman, Bajc, Kaja, Blanchette, Marie, Cherf, Gerald Maxwell, Earr, Timothy K., Gill, Audrey, Huynh, David, Joy, David, Knight, Kristen N., Lac, Diana, Leung, Amy Wing-Sze, Lexa, Katrina W., Liau, Nicholas P. D., Becerra, Isabel, Malfavon, Mario, McInnes, Joseph, Nguyen, Hoang N., Lozano, Edwin I., Pizzo, Michelle E., Roche, Elysia, Sacayon, Patricia, Calvert, Meredith E. K., Daneman, Richard, Dennis, Mark S., Duque, Joseph, Gadkar, Kapil, Lewcock, Joseph W., Mahon, Cathal S., Meisner, René, Solanoy, Hilda, Thorne, Robert G., Watts, Ryan J., Zuchero, Y. Joy Yu, Kariolis, Mihalis S.

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Twisted amide electrophiles enable cyclic peptide sequencing von Zaretsky, Serge, Rai, Vishal, Gish, Gerald, Forbes, Matthew W, Kofler, Michael, Yu, Joy C Y, Tan, Joanne, Hickey, Jennifer L, Pawson, Tony, Yudin, Andrei K

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Neurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neurons von Yu, Y Joy, Arttamangkul, Seksiri, Evans, Christopher J, Williams, John T, von Zastrow, Mark

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Morphine promotes rapid, arrestin-dependent endocytosis of mu-opioid receptors in striatal neurons von Haberstock-Debic, Helena, Kim, Kyung-Ah, Yu, Y Joy, von Zastrow, Mark

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Rapid delivery of internalized signaling receptors to the somatodendritic surface by sequence-specific local insertion von Yu, Y Joy, Dhavan, Rani, Chevalier, Michael W, Yudowski, Guillermo A, von Zastrow, Mark

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Soluble Dendron-Functionalized Carbon Nanotubes:  Preparation, Characterization, and Properties von Sun, Ya-Ping, Huang, Weijie, Lin, Yi, Fu, Kefu, Kitaygorodskiy, Alex, Riddle, Lance A, Yu, Y. Joy, Carroll, David L

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Characterization of A Sensitive Mouse Aβ40 Pd Biomarker Assay for Alzheimer’s Disease Drug Development in Wild-Type Mice von Lu, Yanmei, Hoyte, Kwame, Montgomery, William H, Luk, Wilman, He, Dongping, Meilandt, William J, Zuchero, Y Joy Yu, Atwal, Jasvinder K, Scearce-Levie, Kimberly, Watts, Ryan J, DeForge, Laura E

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A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models von van Lengerich, Bettina, Zhan, Lihong, Xia, Dan, Chan, Darren, Joy, David, Park, Joshua I., Tatarakis, David, Calvert, Meredith, Hummel, Selina, Lianoglou, Steve, Pizzo, Michelle E., Prorok, Rachel, Thomsen, Elliot, Bartos, Laura M., Beumers, Philipp, Capell, Anja, Davis, Sonnet S., de Weerd, Lis, Dugas, Jason C., Duque, Joseph, Earr, Timothy, Gadkar, Kapil, Giese, Tina, Gill, Audrey, Gnörich, Johannes, Ha, Connie, Kannuswamy, Malavika, Kim, Do Jin, Kunte, Sebastian T., Kunze, Lea H., Lac, Diana, Lechtenberg, Kendra, Leung, Amy Wing-Sze, Liang, Chun-Chi, Lopez, Isabel, McQuade, Paul, Modi, Anuja, Torres, Vanessa O., Nguyen, Hoang N., Pesämaa, Ida, Propson, Nicholas, Reich, Marvin, Robles-Colmenares, Yaneth, Schlepckow, Kai, Slemann, Luna, Solanoy, Hilda, Suh, Jung H., Thorne, Robert G., Vieira, Chandler, Wind-Mark, Karin, Xiong, Ken, Zuchero, Y. Joy Yu, Diaz, Dolo, Dennis, Mark S., Huang, Fen, Scearce-Levie, Kimberly, Watts, Ryan J., Haass, Christian, Lewcock, Joseph W., Di Paolo, Gilbert, Brendel, Matthias, Sanchez, Pascal E., Monroe, Kathryn M.

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Twisted amide electrophiles enable cyclic peptide sequencingElectronic supplementary information (ESI) available: Methods and CID/MS2 analysis. See DOI: 10.1039/c5ob01050k von Zaretsky, Serge, Rai, Vishal, Gish, Gerald, Forbes, Matthew W, Kofler, Michael, Yu, Joy C. Y, Tan, Joanne, Hickey, Jennifer L, Pawson, Tony, Yudin, Andrei K

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MODIFICACIÓN DE POLIPÉPTIDOS, BIBLIOTECAS Y CADENA PESADA CD98 MODIFICADA Y POLIPÉPTIDOS DE UNIÓN AL RECEPTOR DE TRANSFERRINA von DENNIS, MARK S, CHEW, KYLIE S, GU, ZHENYU, WELLS, ROBERT C, ZUCHERO, JOY YU, TRAN, HAI L, AKKAPEDDI, PADMA, CHERF, GERALD MAXWELL, KARIOLIS, MIHALIS S

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POLIPÉPTIDOS ANTI-HER2 Y MÉTODOS DE USO DE LOS MISMOS von DENNIS, MARK S, ZUCHERO, JOY YU, LEWCOCK, JOSEPH W, SOCKOLOSKY, JONATHAN, KWAN, WANDA

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CONJUGADOS DE OLIGONUCLEÓTIDOS DIRIGIDO AL RECEPTOR DE TRANSFERRINA von DEVOS, SARAH L, BARKER, SCARLETT, WELLS, ROBERT C, ESTRADA, ANTHONY A, SHAN, LU, NILEWSKI, LIZANNE G, THAYER, MAI B, KARIOLIS, MIHALIS S, DENNIS, MARK S, MAHON, CATHAL S, ZUCHERO, JOY YU, TONG, RAYMOND KA HANG, TRAN, HAI L, PARK, JOSHUA I

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