Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging von Young, Kira, Eudy, Elizabeth, Bell, Rebecca, Loberg, Matthew A., Stearns, Tim, Sharma, Devyani, Velten, Lars, Haas, Simon, Filippi, Marie-Dominique, Trowbridge, Jennifer J.

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Progressive alterations in multipotent hematopoietic progenitors underlie lymphoid cell loss in aging von Young, Kira, Borikar, Sneha, Bell, Rebecca, Kuffler, Lauren, Philip, Vivek, Trowbridge, Jennifer J

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Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis von SanMiguel, Jennifer M, Eudy, Elizabeth, Loberg, Matthew A, Young, Kira A, Mistry, Jayna J, Mujica, Kristina D, Schwartz, Logan S, Stearns, Timothy M, Challen, Grant A, Trowbridge, Jennifer J

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Transcriptional and functional consequences of Oncostatin M signaling on young Dnmt3a-mutant hematopoietic stem cells von Schwartz, Logan S., Young, Kira A., Stearns, Timothy M., Boyer, Nathan, Mujica, Kristina D., Trowbridge, Jennifer J.

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Leukaemia cell of origin identified by chromatin landscape of bulk tumour cells von George, Joshy, Uyar, Asli, Young, Kira, Kuffler, Lauren, Waldron-Francis, Kaiden, Marquez, Eladio, Ucar, Duygu, Trowbridge, Jennifer J.

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BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses von Young, Kira, Tweedie, Eric, Conley, Barbara, Ames, Jacquelyn, FitzSimons, MaryLynn, Brooks, Peter, Liaw, Lucy, Vary, Calvin P H

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BMP9 regulates endoglin-dependent chemokine responses in endothelial cells von Young, Kira, Conley, Barbara, Romero, Diana, Tweedie, Eric, O'Neill, Christine, Pinz, Ilka, Brogan, Louise, Lindner, Volkhard, Liaw, Lucy, Vary, Calvin P.H.

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Investigating the Effects of Alltech Crop Science (ACS) Products on Plant Defence against Root-Knot Nematode Infestation von Pulavarty, Anusha, Singh, Ankit, Young, Kira, Horgan, Karina, Kakouli-Duarte, Thomais

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Endoglin Regulates Cancer-Stromal Cell Interactions in Prostate Tumors von ROMERO, Diana, O'NEILL, Christine, TERZIC, Aleksandra, CONTOIS, Liangru, YOUNG, Kira, CONLEY, Barbara A, BERGAN, Raymond C, BROOKS, Peter C, VARY, Calvin P. H

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Elevated Functional Hematopoietic Stem and Progenitor Cells in the Peripheral Blood of G-CSF-Mobilized Dnmt3a-Mutant Mice von Young, Kira A., Nye, Griffin J., Trowbridge, Jennifer J.

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2012 – DNMT3A-MUTANT HEMATOPOIETIC PROGENITOR CELLS INDUCE SENESCENCE OF BONE MARROW STROMA TO ACCELERATE CLONAL HEMATOPOIESIS AND TRANSFORMATION TO ACUTE MYELOID LEUKEMIA von Mistry, Jayna, Young, Kira, Trowbridge, Jennifer

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Bone Marrow Stromal Cell Senescence Induced By Dnmt3a-Mutant Hematopoietic Stem and Progenitor Cells Accelerates Clonal Hematopoiesis and Progression to Leukemia von Mistry, Jayna J, Young, Kira A, Trowbridge, Jennifer J

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Hand in hand: intrinsic and extrinsic drivers of aging and clonal hematopoiesis von SanMiguel, Jennifer M., Young, Kira, Trowbridge, Jennifer J.

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3190 – ACCOUNTING FOR BIOLOGICAL VARIATION IN SCRNA-SEQ QUALITY CONTROL METRICS RETAINS DISTINCT NICHE AND HEMATOPOIETIC CELL TYPES von Telpoukhovskaia, Maria, Young, Kira, Mistry, Jayna, Trowbridge, Jennifer

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Bone Marrow Microenvironment and Hematopoietic Cell Types Are Differentially Affected By Transcriptomic Quality Control Filtering Metrics in Single Cell Data von Telpoukhovskaia, Maria A., Young, Kira A., Mistry, Jayna J., Trowbridge, Jennifer J.

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Oncostatin M (OSM) Regulates an Inflammatory Cytokine Network in Dnmt3a-Mutant Hematopoietic Stem Cells von Schwartz, Logan Sari, Young, Kira A., Stearns, Tim, Boyer, Nathan, Mujica, Kristina, Trowbridge, Jennifer J.

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2021 – ALTERED MITOCHONDRIAL METABOLISM IN DNMT3A-MUTANT HEMATOPOIETIC STEM CELLS UNDERLIES THEIR SELECTIVE ADVANTAGE DURING AGING von Trowbridge, Jennifer, Young, Kira, Mistry, Jayna, Chavez, James, Pietras, Eric

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3184 – ONCOSTATIN M SIGNALING MEDIATES DNMT3A-MUTANT HEMATOPOIETIC STEM CELL FITNESS IN THE AGED BONE MARROW MICROENVIRONMENT von Schwartz, Logan, Young, Kira, Loberg, Matthew, Stearns, Tim, Trowbridge, Jennifer

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3132 – PRODUCTION OF ALARMINS S100A8/A9 BY DNMT3A-MUTANT HEMATOPOIETIC CELLS CAUSES MESENCHYMAL STROMAL CELL SENESCENCE AND SEEDS A PRO-INFLAMMATORY ENVIRONMENT IN CLONAL HEMATOPOI... von Mistry, Jayna, Young, Kira, Maestre, Ines Fernandez, Levine, Ross, Trowbridge, Jennifer

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Robust Mitochondrial Metabolism Provides a Fitness Advantage to Dnmt3a-Mutant Hematopoietic Stem Cells in the Context of Aging von Young, Kira A, Mistry, Jayna J, Chavez, James, Pietras, Eric, Trowbridge, Jennifer J

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