LSD1 is required for euchromatic origin firing and replication timing von Wang, Yue, Huang, Yunchao, Cheng, Edith, Liu, Xinhua, Zhang, Yu, Yang, Jianguo, Young, Jordan T. F., Brown, Grant W., Yang, Xiaohan, Shang, Yongfeng

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A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice von Escribano-Díaz, Cristina, Orthwein, Alexandre, Fradet-Turcotte, Amélie, Xing, Mengtan, Young, Jordan T.F., Tkáč, Ján, Cook, Michael A., Rosebrock, Adam P., Munro, Meagan, Canny, Marella D., Xu, Dongyi, Durocher, Daniel

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The CIP2A-TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer von Adam, Salomé, Rossi, Silvia Emma, Moatti, Nathalie, De Marco Zompit, Mara, Xue, Yibo, Ng, Timothy F, Álvarez-Quilón, Alejandro, Desjardins, Jessica, Bhaskaran, Vivek, Martino, Giovanni, Setiaputra, Dheva, Noordermeer, Sylvie M, Ohsumi, Toshiro K, Hustedt, Nicole, Szilard, Rachel K, Chaudhary, Natasha, Munro, Meagan, Veloso, Artur, Melo, Henrique, Yin, Shou Yun, Papp, Robert, Young, Jordan T F, Zinda, Michael, Stucki, Manuel, Durocher, Daniel

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The MMS22L-TONSL Complex Mediates Recovery from Replication Stress and Homologous Recombination von O'Donnell, Lara, Panier, Stephanie, Wildenhain, Jan, Tkach, Johnny M., Al-Hakim, Abdallah, Landry, Marie-Claude, Escribano-Diaz, Cristina, Szilard, Rachel K., Young, Jordan T.F., Munro, Meagan, Canny, Marella D., Kolas, Nadine K., Zhang, Wei, Harding, Shane M., Ylanko, Jarkko, Mendez, Megan, Mullin, Michael, Sun, Thomas, Habermann, Bianca, Datti, Alessandro, Bristow, Robert G., Gingras, Anne-Claude, Tyers, Michael D., Brown, Grant W., Durocher, Daniel

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CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition von Gallo, David, Young, Jordan T. F., Fourtounis, Jimmy, Martino, Giovanni, Álvarez-Quilón, Alejandro, Bernier, Cynthia, Duffy, Nicole M., Papp, Robert, Roulston, Anne, Stocco, Rino, Szychowski, Janek, Veloso, Artur, Alam, Hunain, Baruah, Prasamit S., Fortin, Alexanne Bonneau, Bowlan, Julian, Chaudhary, Natasha, Desjardins, Jessica, Dietrich, Evelyne, Fournier, Sara, Fugère-Desjardins, Chloe, Goullet de Rugy, Theo, Leclaire, Marie-Eve, Liu, Bingcan, Bhaskaran, Vivek, Mamane, Yael, Melo, Henrique, Nicolas, Olivier, Singhania, Akul, Szilard, Rachel K., Tkáč, Ján, Yin, Shou Yun, Morris, Stephen J., Zinda, Michael, Marshall, C. Gary, Durocher, Daniel

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Profound synthetic lethality between SMARCAL1 and FANCM von Feng, Sumin, Liu, Kaiwen, Shang, Jinfeng, Hoeg, Lisa, Pastore, Graziana, Yang, William, Roy, Sabrina, Sastre-Moreno, Guillermo, Young, Jordan T.F., Wu, Wei, Xu, Dongyi, Durocher, Daniel

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RP-3500: A Novel, Potent, and Selective ATR Inhibitor that is Effective in Preclinical Models as a Monotherapy and in Combination with PARP Inhibitors von Roulston, Anne, Zimmermann, Michal, Papp, Robert, Skeldon, Alexander, Pellerin, Charles, Dumas-Bérube, Émilie, Dumais, Valerie, Dorich, Stéphane, Fader, Lee D, Fournier, Sara, Li, Li, Leclaire, Marie-Eve, Yin, Shou Yun, Chefson, Amandine, Alam, Hunain, Yang, William, Fugère-Desjardins, Chloe, Vignini-Hammond, Sabrina, Skorey, Kathryn, Mulani, Amina, Rimkunas, Victoria, Veloso, Artur, Hamel, Martine, Stocco, Rino, Mamane, Yael, Li, Zuomei, Young, Jordan T F, Zinda, Michael, Black, W Cameron

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HELB Is a Feedback Inhibitor of DNA End Resection von Tkáč, Ján, Xu, Guotai, Adhikary, Hemanta, Young, Jordan T.F., Gallo, David, Escribano-Díaz, Cristina, Krietsch, Jana, Orthwein, Alexandre, Munro, Meagan, Sol, Wendy, Al-Hakim, Abdallah, Lin, Zhen-Yuan, Jonkers, Jos, Borst, Piet, Brown, Grant W., Gingras, Anne-Claude, Rottenberg, Sven, Masson, Jean-Yves, Durocher, Daniel

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A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities von Vizeacoumar, Franco J, Arnold, Roland, Vizeacoumar, Frederick S, Chandrashekhar, Megha, Buzina, Alla, Young, Jordan T F, Kwan, Julian H M, Sayad, Azin, Mero, Patricia, Lawo, Steffen, Tanaka, Hiromasa, Brown, Kevin R, Baryshnikova, Anastasia, Mak, Anthony B, Fedyshyn, Yaroslav, Wang, Yadong, Brito, Glauber C, Kasimer, Dahlia, Makhnevych, Taras, Ketela, Troy, Datti, Alessandro, Babu, Mohan, Emili, Andrew, Pelletier, Laurence, Wrana, Jeff, Wainberg, Zev, Kim, Philip M, Rottapel, Robert, O'Brien, Catherine A, Andrews, Brenda, Boone, Charles, Moffat, Jason

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Proteasome inhibition induces hsp30 and hsp70 gene expression as well as the acquisition of thermotolerance in Xenopus laevis A6 cells von Young, Jordan T. F., Heikkila, John J.

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Simultaneous exposure of Xenopus A6 kidney epithelial cells to concurrent mild sodium arsenite and heat stress results in enhanced hsp30 and hsp70 gene expression and the acquisiti... von Young, Jordan T.F., Gauley, Julie, Heikkila, John J.

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Guiding ATR and PARP inhibitor combinations with chemogenomic screens von Zimmermann, Michal, Bernier, Cynthia, Kaiser, Beatrice, Fournier, Sara, Li, Li, Desjardins, Jessica, Skeldon, Alexander, Rimkunas, Victoria, Veloso, Artur, Young, Jordan T.F., Roulston, Anne, Zinda, Michael

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Guiding ATR and PARP inhibitor combinationswith chemogenomic screens von Zimmermann, Michal, Bernier, Cynthia, Kaiser, Beatrice, Fournier, Sara, Li, Li, Desjardins, Jessica, Skeldon, Alexander, Rimkunas, Victoria, Veloso, Artur, Young, Jordan T F, Roulston, Anne, Zinda, Michael

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Endogenous DNA 3′ Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 Nuclease von Álvarez-Quilón, Alejandro, Wojtaszek, Jessica L., Mathieu, Marie-Claude, Patel, Tejas, Appel, C. Denise, Hustedt, Nicole, Rossi, Silvia Emma, Wallace, Bret D., Setiaputra, Dheva, Adam, Salomé, Ohashi, Yota, Melo, Henrique, Cho, Tiffany, Gervais, Christian, Muñoz, Ivan M., Grazzini, Eric, Young, Jordan T.F., Rouse, John, Zinda, Michael, Williams, R. Scott, Durocher, Daniel

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Abstract C163: KRAS alterations combined with TP53 mutations as novel synthetic lethal genomic lesions for PKMYT1 inhibition von Hyer, Marc L., Fourtounis, Jimmy, Gallo, David, Bhaskaran, Vivek, Stocco, Rino, Kryczka, Rosie, Save, Sai, Burston, Helen, Nicolas, Olivier, Morris, Stephen, Roulston, Anne, Young, Jordan T. F., Zimmermann, Michal, Marshall, C. Gary, Veloso, Artur, Aguado-Fraile, Elia

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The CIP2A–TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer von Adam, Salomé, Rossi, Silvia Emma, Moatti, Nathalie, De Marco Zompit, Mara, Xue, Yibo, Ng, Timothy F, Álvarez-Quilón, Alejandro, Desjardins, Jessica, Bhaskaran, Vivek, Martino, Giovanni, Setiaputra, Dheva, Noordermeer, Sylvie M, Ohsumi, Toshiro K, Hustedt, Nicole, Szilard, Rachel K, Chaudhary, Natasha, Munro, Meagan, Veloso, Artur, Melo, Henrique, Yin, Shou Yun, Papp, Robert, Young, Jordan T F, Zinda, Michael, Stucki, Manuel, Durocher, Daniel

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European Society for Medical Oncology (ESMO) position paper on supportive and palliative care von Jordan, K., Aapro, M., Kaasa, S., Ripamonti, C.I., Scotté, F., Strasser, F., Young, A., Bruera, E., Herrstedt, J., Keefe, D., Laird, B., Walsh, D., Douillard, J.Y., Cervantes, A.

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Venous thromboembolism in cancer patients: ESMO Clinical Practice Guideline von Falanga, A., Ay, C., Di Nisio, M., Gerotziafas, G., Jara-Palomares, L., Langer, F., Lecumberri, R., Mandala, M., Maraveyas, A., Pabinger, I., Sinn, M., Syrigos, K., Young, A., Jordan, K.

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evolution of self-control von MacLean, Evan L, Hare, Brian, Nunn, Charles L, Addessi, Elsa, Amici, Federica, Anderson, Rindy C, Aureli, Filippo, Baker, Joseph M, Bania, Amanda E, Barnard, Allison M, Boogert, Neeltje J, Brannon, Elizabeth M, Bray, Emily E, Bray, Joel, Brent, Lauren J N, Burkart, Judith M, Call, Josep, Cantlon, Jessica F, Cheke, Lucy G, Clayton, Nicola S, Delgado, Mikel M, DiVincenti, Louis J, Fujita, Kazuo, Herrmann, Esther, Hiramatsu, Chihiro, Jacobs, Lucia F, Jordan, Kerry E, Laude, Jennifer R, Leimgruber, Kristin L, Messer, Emily J E, Moura, Antonio C de A, Ostojić, Ljerka, Picard, Alejandra, Platt, Michael L, Plotnik, Joshua M, Range, Friederike, Reader, Simon M, Reddy, Rachna B, Sandel, Aaron A, Santos, Laurie R, Schumann, Katrin, Seed, Amanda M, Sewall, Kendra B, Shaw, Rachael C, Slocombe, Katie E, Su, Yanjie, Takimoto, Ayaka, Tan, Jingzhi, Tao, Ruoting, van Schaik, Carel P, Virányi, Zsófia, Visalberghi, Elisabetta, Wade, Jordan C, Watanabe, Arii, Widness, Jane, Young, Julie K, Zentall, Thomas R, Zhao, Yini

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Inhibiting Oxygen Release from Li‐rich, Mn‐rich Layered Oxides at the Surface with a Solution Processable Oxygen Scavenger Polymer von Kim, Se Young, Park, Chan Sun, Hosseini, Shahrzad, Lampert, Jordan, Kim, Young Jin, Nazar, Linda F.

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