Biophysical characterization of blood coagulation factor VIII binding to lipid nanodiscs that mimic activated platelet surfaces von Avery, Nathan G., Young, Isabelle R., Lu, Selena, Vaughan, Jordan D., Korus, Patrick S., Richardson, Tera N., Childers, Kenneth C., Smirnov, Serge L., Spiegel, P. Clint

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Suppression of Cytokine Signaling by SOCS3: Characterization of the Mode of Inhibition and the Basis of Its Specificity von Babon, Jeffrey J., Kershaw, Nadia J., Murphy, James M., Varghese, Leila N., Laktyushin, Artem, Young, Samuel N., Lucet, Isabelle S., Norton, Raymond S., Nicola, Nicos A.

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Cohort Profile: The Canadian Longitudinal Study on Aging (CLSA) von Raina, Parminder, Wolfson, Christina, Kirkland, Susan, Griffith, Lauren E, Balion, Cynthia, Cossette, Benoȋt, Dionne, Isabelle, Hofer, Scott, Hogan, David, van den Heuvel, E R, Liu-Ambrose, Teresa, Menec, Verena, Mugford, Gerald, Patterson, Christopher, Payette, Hélène, Richards, Brent, Shannon, Harry, Sheets, Debra, Taler, Vanessa, Thompson, Mary, Tuokko, Holly, Wister, Andrew, Wu, Changbao, Young, Lynne

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Folding and misfolding of potassium channel monomers during assembly and tetramerization von Song, Kevin C., Molina, Andrew V., Chen, Ruofan, Gagnon, Isabelle A., Koh, Young Hoon, Roux, Benoît, Sosnick, Tobin R.

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Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix von Oliver, Michael R., Horne, Christopher R., Shrestha, Safal, Keown, Jeremy R., Liang, Lung-Yu, Young, Samuel N., Sandow, Jarrod J., Webb, Andrew I., Goldstone, David C., Lucet, Isabelle S., Kannan, Natarajan, Metcalf, Peter, Murphy, James M.

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Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery von Mazer, C. David, Whitlock, Richard P, Fergusson, Dean A, Hall, Judith, Belley-Cote, Emilie, Connolly, Katherine, Khanykin, Boris, Gregory, Alexander J, de Médicis, Étienne, McGuinness, Shay, Royse, Alistair, Carrier, François M, Young, Paul J, Villar, Juan C, Grocott, Hilary P, Seeberger, Manfred D, Fremes, Stephen, Lellouche, François, Syed, Summer, Byrne, Kelly, Bagshaw, Sean M, Hwang, Nian C, Mehta, Chirag, Painter, Thomas W, Royse, Colin, Verma, Subodh, Hare, Gregory M.T, Cohen, Ashley, Thorpe, Kevin E, Jüni, Peter, Shehata, Nadine

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Stereotactic body radiotherapy versus conventional external beam radiotherapy in patients with painful spinal metastases: an open-label, multicentre, randomised, controlled, phase... von Sahgal, Arjun, Myrehaug, Sten D, Siva, Shankar, Masucci, Giuseppina L, Maralani, Pejman J, Brundage, Michael, Butler, James, Chow, Edward, Fehlings, Michael G, Foote, Mathew, Gabos, Zsolt, Greenspoon, Jeffrey, Kerba, Marc, Lee, Young, Liu, Mitchell, Liu, Stanley K, Thibault, Isabelle, Wong, Rebecca K, Hum, Maaike, Ding, Keyue, Parulekar, Wendy R

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Adjuvant Trastuzumab in HER2-Positive Breast Cancer von Slamon, Dennis, Eiermann, Wolfgang, Robert, Nicholas, Pienkowski, Tadeusz, Martin, Miguel, Press, Michael, Mackey, John, Glaspy, John, Chan, Arlene, Pawlicki, Marek, Pinter, Tamas, Valero, Vicente, Liu, Mei-Ching, Sauter, Guido, von Minckwitz, Gunter, Visco, Frances, Bee, Valerie, Buyse, Marc, Bendahmane, Belguendouz, Tabah-Fisch, Isabelle, Lindsay, Mary-Ann, Riva, Alessandro, Crown, John

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Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery von Mazer, C. David, Whitlock, Richard P, Fergusson, Dean A, Belley-Cote, Emilie, Connolly, Katherine, Khanykin, Boris, Gregory, Alexander J, de Médicis, Étienne, Carrier, François M, McGuinness, Shay, Young, Paul J, Byrne, Kelly, Villar, Juan C, Royse, Alistair, Grocott, Hilary P, Seeberger, Manfred D, Mehta, Chirag, Lellouche, François, Hare, Gregory M.T, Painter, Thomas W, Fremes, Stephen, Syed, Summer, Bagshaw, Sean M, Hwang, Nian-Chih, Royse, Colin, Hall, Judith, Dai, David, Mistry, Nikhil, Thorpe, Kevin, Verma, Subodh, Jüni, Peter, Shehata, Nadine

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Rapid assessment of a novel series of selective CB2 agonists using parallel synthesis protocols: A Lipophilic Efficiency (LipE) analysis von Ryckmans, Thomas, Edwards, Martin P., Horne, Val A., Correia, Ana Monica, Owen, Dafydd R., Thompson, Lisa R., Tran, Isabelle, Tutt, Michelle F., Young, Tim

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A Local Allosteric Network in Heat Shock Protein 70 (Hsp70) Links Inhibitor Binding to Enzyme Activity and Distal Protein–Protein Interactions von Rinaldi, Silvia, Assimon, Victoria A, Young, Zapporah T, Morra, Giulia, Shao, Hao, Taylor, Isabelle R, Gestwicki, Jason E, Colombo, Giorgio

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In vivo models of subclonal oncogenesis and dependency in hematopoietic malignancy von Bowman, Robert L., Dunbar, Andrew J., Mishra, Tanmay, Xiao, Wenbin, Waarts, Michael R., Maestre, Inés Fernández, Eisman, Shira E., Cai, Louise, Mowla, Shoron, Shah, Nisargbhai, Youn, Angela, Bennett, Laura, Fontenard, Suean, Gounder, Shreeya, Gandhi, Anushka, Bowman, Michael, O’Connor, Kavi, Zaroogian, Zachary, Sánchez-Vela, Pablo, Martinez Benitez, Anthony R., Werewski, Matthew, Park, Young, Csete, Isabelle S., Krishnan, Aishwarya, Lee, Darren, Boorady, Nayla, Potts, Chad R., Jenkins, Matthew T., Cai, Sheng F., Carroll, Martin P., Meyer, Sara E., Miles, Linde A., Ferrell, P. Brent, Trowbridge, Jennifer J., Levine, Ross L.

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The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs von Liang, Lung-Yu, Roy, Michael, Horne, Christopher R., Sandow, Jarrod J., Surudoi, Minglyanna, Dagley, Laura F., Young, Samuel N., Dite, Toby, Babon, Jeffrey J., Janes, Peter W., Patel, Onisha, Murphy, James M., Lucet, Isabelle S.

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Robust SARS-CoV-2 antibody and T cell immunity following three COVID-19 vaccine doses in inflammatory bowel disease patients receiving anti-TNF or alternative treatments von Zhang, Eva, Nguyen, Thi H O, Allen, Lilith F, Kedzierski, Lukasz, Rowntree, Louise C, Chang, So Young, Zhang, Wuji, Habel, Jennifer R, Foo, Isabelle J, Menon, Tejas, Mitchell, Jeni, Leong, Rupert W, Bond, Katherine, Williamson, Deborah A, Kedzierska, Katherine, Christensen, Britt

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Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4 + hemangiocytes von Rafii, Shahin, Jin, David K, Shido, Koji, Kopp, Hans-Georg, Petit, Isabelle, Shmelkov, Sergey V, Young, Lauren M, Hooper, Andrea T, Amano, Hideki, Avecilla, Scott T, Heissig, Beate, Hattori, Koichi, Zhang, Fan, Hicklin, Daniel J, Wu, Yan, Zhu, Zhenping, Dunn, Ashley, Salari, Hassan, Werb, Zena, Hackett, Neil R, Crystal, Ronald G, Lyden, David

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A head‐to‐head comparison of ixekizumab vs. guselkumab in patients with moderate‐to‐severe plaque psoriasis: 12‐week efficacy, safety and speed of response from a randomized, doubl... von Papp, K., Gottlieb, A., Reich, K., Maari, C., Gordon, K.B., Lima, R.G., Elmaraghy, H., Gallo, G., Renda, L., Park, S.Y., Burge, R., Bagel, J., Vender, Ronald, Hong, Chih‐Ho, Langley, Richard L., Albrecht, Lorne, Guenther, Lyn, Papp, Kim, Singh Ohson, Kamal K., Barber, Kirk, Lynde, Charles, Gupta, Aditya, Rosoph, Leslie, Gauthier, Jean‐Sébastien, Gooderham, Melinda, Wasel, Norman, Wiseman, Marni, Greenstein, David, Jarell, Abel, Moon, Charles, Bukhalo, Michael, Moore, Angela, Hamilton, Tiffani K., Gewirtzman, Aron, Hazan, Lydie, Crowley, Jeffrey, Teller, Craig, Smith, Stacy R., Christine Lee, M., Lee, Patricia, Dhawan, Sunil, Leonardi, Craig, Jesus, Amarilis Perez‐De, McFalda, Wendy, Fretzin, Scott, Schlesinger, Todd, Gottlieb, Scott, Jenkin, Peter, Gharib, Rola, Davis, Steven, Draelos, Zoe Diana, Godwin, Lloyd, Landis, Megan, Sanchez‐Rivera, Samuel, Fivenson, David, Kerdel, Francisco, Forman, Seth B., Gonzalez‐Chavez, Jose, Boyce, Brent, Stein‐Gold, Linda, Hudson, Charles, Brown, Constance, Coggi, James, Feser, Christina, McCune, Mark, Madkan, Vandana, Shipp, Dana Maxwell, Soto‐Raices, Oscar, Cather, Jennifer, Miller, Scott, Scott, John, Young, Douglas, Yokum, Kelley, McCracken, Gary, McElgunn, Patrick, Herrmann, James, Appel, James, Barranco, Elizabeth, Cauthen, Ashley, Sadick, Neil, De La Torre, Eneida, Taylor, Kelly, Harris, Holly Hake, Soung, Jennifer, Dimitropoulos, Vassilios, Miller, Stephen, Barnes, Cathy, Jumean‐Haddad, Rawan, Guenthner, Scott, Laquer, Vivian, Jacobs, Shahram, Nahm, Walter, Korman, Neil, Elewski, Boni, Ferris, Laura, Duffin, Kristina Callis, Pariser, David, Johnson, Brian, Travers, Jeffrey, Fried, Richard

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Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studi... von Paciorek, Christopher J, Afsana, Kaosar, Alarouj, Monira, Andersen, Lars Bo, Arku, Raphael E, Azevedo, Ana, Baran, Joanna, Batista, Rosangela L, Beaglehole, Robert, Bhagyalaxmi, Aroor, Bia, Daniel, Bongard, Vanina, Breckenkamp, Juergen, Brewster, Lizzy M, Capuano, Vincenzo, Chan, Angelique W, Chen, Zhengming, Clarke, Janine, Csilla, Semánová, De Ridder, David, DeGennaro, Vincent Jr, Deschamps, Valérie, Donati, Maria Benedetta, Dushpanova, Anar, Eftekhar, Ebrahim, Erem, Cihangir, Farjam, Mojtaba, Farzadfar, Farshad, Fernandes, Romulo A, Francis, Damian K, Frontera, Guillermo, Furusawa, Takuro, Godos, Justyna, Gómez, Santiago F, Grodzicki, Tomasz, Guo, Yin, Gutiérrez-González, Enrique, Gutierrez, Laura, Hanif, Abu AM, Henriques, Ana, Jasienska, Grazyna, Jiang, Chao Qiang, Joffres, Michel, Kavousi, Maryam, Keinänen-Kiukaanniemi, Sirkka, Kelishadi, Roya, Khader, Yousef Saleh, Korzycka, Magdalena, Kulaga, Zbigniew, Le Nguyen Bao, Khanh, Le, Tuyen D, Machado-Coelho, George LL, Markidou Ioannidou, Eliza, Martos, Eva, Medzioniene, Jurate, Mehrparvar, Amir Houshang, Miquel, Juan Francisco, Mišigoj-Durakovic, Marjeta, Mocanu, Veronica, Moghaddam, Sahar Saeedi, Møller, Niels C, Moschonis, George, Msyamboza, Kelias P, Mukhtorova, Parvina, Ohlsson, Claes, Olafsson, Örn, Oliveira, Isabel O, Otero, Johanna A, Paiva, Karina Mary de, Porta, Miquel, Pradeepa, Rajendra, Revilla, Luis, Richter, Adrian, Rivera, Juan A, Rusakova, Iuliia A, Russo, Paola, Sandjaja, Shaw, Jonathan E, Shengelia, Lela, Si-Ramlee, Khairil, Silva, Diego Augusto Santos, Sjöström, Michael, Slowikowska-Hilczer, Jolanta, So, Hung-Kwan, Sofat, Reecha, Sonestedt, Emily, Spinelli, Angela, Stavreski, Bill, Strufaldi, Maria Wany, Sturua, Lela, Sung, Yn-Tz, Sunyer, Jordi, Tello, Tania, van der Schouw, Yvonne T, Voutilainen, Sari, Wareham, Nicholas, Weber, Adelheid, Zhang, Luxia, Zhang, Zhen-Yu, Zhu, Dan

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Human Equilibrative Nucleoside Transporter 1 and Human Concentrative Nucleoside Transporter 3 Predict Survival after Adjuvant Gemcitabine Therapy in Resected Pancreatic Adenocarcin... von Maréchal, Raphaël, Mackey, John R, Lai, Raymond, Demetter, Pieter, Peeters, Marc, Polus, Marc, Cass, Carol E, Young, James, Salmon, Isabelle, Devière, Jacques, Van Laethem, Jean-Luc

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Whole genome sequencing reveals that genetic conditions are frequent in intensively ill children von French, Courtney E., Delon, Isabelle, Dolling, Helen, Sanchis-Juan, Alba, Shamardina, Olga, Mégy, Karyn, Abbs, Stephen, Austin, Topun, Bowdin, Sarah, Branco, Ricardo G., Firth, Helen, Rowitch, David H., Raymond, F. Lucy

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Tryptophan scanning mutagenesis as a way to mimic the compound-bound state and probe the selectivity of allosteric inhibitors in cells von Taylor, Isabelle R, Assimon, Victoria A, Kuo, Szu Yu, Rinaldi, Silvia, Li, Xiaokai, Young, Zapporah T, Morra, Giulia, Green, Keith, Nguyen, Daniel, Shao, Hao, Garneau-Tsodikova, Sylvie, Colombo, Giorgio, Gestwicki, Jason E

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