Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis von Liu, Xiaoguang, Nie, Litong, Zhang, Yilei, Yan, Yuelong, Wang, Chao, Colic, Medina, Olszewski, Kellen, Horbath, Amber, Chen, Xiong, Lei, Guang, Mao, Chao, Wu, Shiqi, Zhuang, Li, Poyurovsky, Masha V., James You, M., Hart, Traver, Billadeau, Daniel D., Chen, Junjie, Gan, Boyi

Volltext

Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer von Liu, Xiaoguang, Olszewski, Kellen, Zhang, Yilei, Lim, Esther W., Shi, Jiejun, Zhang, Xiaoshan, Zhang, Jie, Lee, Hyemin, Koppula, Pranavi, Lei, Guang, Zhuang, Li, You, M. James, Fang, Bingliang, Li, Wei, Metallo, Christian M., Poyurovsky, Masha V., Gan, Boyi

Volltext

SLC7A11 expression level dictates differential responses to oxidative stress in cancer cells von Yan, Yuelong, Teng, Hongqi, Hang, Qinglei, Kondiparthi, Lavanya, Lei, Guang, Horbath, Amber, Liu, Xiaoguang, Mao, Chao, Wu, Shiqi, Zhuang, Li, James You, M., Poyurovsky, Masha V., Ma, Li, Olszewski, Kellen, Gan, Boyi

Volltext

A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis von Yao, Fan, Deng, Yalan, Zhao, Yang, Mei, Ying, Zhang, Yilei, Liu, Xiaoguang, Martinez, Consuelo, Su, Xiaohua, Rosato, Roberto R., Teng, Hongqi, Hang, Qinglei, Yap, Shannon, Chen, Dahu, Wang, Yumeng, Chen, Mei-Ju May, Zhang, Mutian, Liang, Han, Xie, Dong, Chen, Xin, Zhu, Hao, Chang, Jenny C., You, M. James, Sun, Yutong, Gan, Boyi, Ma, Li

Volltext

Nano-optogenetic engineering of CAR T cells for precision immunotherapy with enhanced safety von Nguyen, Nhung Thi, Huang, Kai, Zeng, Hongxiang, Jing, Ji, Wang, Rui, Fang, Shaohai, Chen, Joyce, Liu, Xin, Huang, Zixian, You, M. James, Rao, Anjana, Huang, Yun, Han, Gang, Zhou, Yubin

Volltext

Hexokinase 2-Mediated Warburg Effect Is Required for PTEN- and p53-Deficiency-Driven Prostate Cancer Growth von Wang, Lei, Xiong, Hua, Wu, Fengxia, Zhang, Yingjie, Wang, Ji, Zhao, Liyan, Guo, Xiaolan, Chang, Li-Ju, Zhang, Yong, You, M. James, Koochekpour, Shahriar, Saleem, Mohammad, Huang, Haojie, Lu, Junxuan, Deng, Yibin

Volltext

The Role of Tumor-Associated Macrophages in Leukemia von Li, Yueyang, You, M. James, Yang, Yaling, Hu, Dongzhi, Tian, Chen

Volltext

The pathologic diagnosis of mantle cell lymphoma von Li, Shaoying, Xu, Jie, You, M James

Volltext

A hypoxia-responsive TRAF6–ATM–H2AX signalling axis promotes HIF1α activation, tumorigenesis and metastasis von Rezaeian, Abdol-Hossein, Li, Chien-Feng, Wu, Ching-Yuan, Zhang, Xian, Delacerda, Jorge, You, M. James, Han, Fei, Cai, Zhen, Jeong, Yun Seong, Jin, Guoxiang, Phan, Liem, Chou, Ping-Chieh, Lee, Mong-Hong, Hung, Mien-Chie, Sarbassov, Dos, Lin, Hui-Kuan

Volltext

DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia von Lin, S, Tian, L, Shen, H, Gu, Y, Li, J-L, Chen, Z, Sun, X, James You, M, Wu, L

Volltext

Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia von Ferrajoli, Alessandra, Shanafelt, Tait D., Ivan, Cristina, Shimizu, Masayoshi, Rabe, Kari G., Nouraee, Nazila, Ikuo, Mariko, Ghosh, Asish K., Lerner, Susan, Rassenti, Laura Z., Xiao, Lianchun, Hu, Jianhua, Reuben, James M., Calin, Steliana, You, M. James, Manning, John T., Wierda, William G., Estrov, Zeev, O'Brien, Susan, Kipps, Thomas J., Keating, Michael J., Kay, Neil E., Calin, George A.

Volltext

BETP degradation simultaneously targets acute myelogenous leukemic stem cells and the microenvironment von Piya, Sujan, Mu, Hong, Bhattacharya, Seemana, Lorenzi, Philip L, Davis, R. Eric, McQueen, Teresa, Ruvolo, Vivian, Baran, Natalia, Wang, Zhiqiang, Qian, Yimin, Crews, Craig M, Konopleva, Marina, Ishizawa, Jo, You, M. James, Kantarjian, Hagop, Andreeff, Michael, Borthakur, Gautam

Volltext

EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis von Yang, Weiwei, Xia, Yan, Cao, Yu, Zheng, Yanhua, Bu, Wen, Zhang, Lin, You, M. James, Koh, Mei Yee, Cote, Gilbert, Aldape, Kenneth, Li, Yi, Verma, Inder M., Chiao, Paul J., Lu, Zhimin

Volltext

Cell-to-cell miRNA transfer: from body homeostasis to therapy von Redis, Roxana S, Calin, Steliana, Yang, Yaling, You, M James, Calin, George A

Volltext

Blastoid high-grade B-cell lymphoma initially presenting in bone marrow: a diagnostic challenge von Khanlari, Mahsa, Medeiros, L. Jeffrey, Lin, Pei, Xu, Jie, You, M. James, Tang, Guilin, Yin, C. Cameron, Wang, Wei, Qiu, Lianqun, Miranda, Roberto N., Bueso-Ramos, Carlos E., Li, Shaoying

Volltext

Unusual presentation of classic Hodgkin lymphoma von Lyapichev, Kirill A., You, M. James

Volltext

Ablation of miR-10b Suppresses Oncogene-Induced Mammary Tumorigenesis and Metastasis and Reactivates Tumor-Suppressive Pathways von Kim, Jongchan, Siverly, Ashley N, Chen, Dahu, Wang, Min, Yuan, Yuan, Wang, Yumeng, Lee, Hyemin, Zhang, Jinsong, Muller, William J, Liang, Han, Gan, Boyi, Yang, Xianbin, Sun, Yutong, You, M James, Ma, Li

Volltext

Targeting the NOTCH1-MYC-CD44 axis in leukemia-initiating cells in T-ALL von Piya, Sujan, Yang, Yaling, Bhattacharya, Seemana, Sharma, Priyanka, Ma, Huaxian, Mu, Hong, He, Hua, Ruvolo, Vivian, Baran, Natalia, Davis, R. Eric, Jain, Abhinav K., Konopleava, Marina, Kantarjian, Hagop, Andreeff, Michael, You, M. James, Borthakur, Gautam

Volltext

PD-L1 expression is associated with ALK positivity and STAT3 activation, but not outcome in patients with systemic anaplastic large cell lymphoma von Shen, Jing, Li, Shaoying, Medeiros, L. Jeffrey, Lin, Pei, Wang, Sa A., Tang, Guilin, Yin, C. Cameron, You, M. James, Khoury, Joseph D., Iyer, Swaminathan P., Miranda, Roberto N., Xu, Jie

Volltext

miR-100 induces epithelial-mesenchymal transition but suppresses tumorigenesis, migration and invasion von Chen, Dahu, Sun, Yutong, Yuan, Yuan, Han, Zhenbo, Zhang, Peijing, Zhang, Jinsong, You, M James, Teruya-Feldstein, Julie, Wang, Min, Gupta, Sumeet, Hung, Mien-Chie, Liang, Han, Ma, Li

Volltext