De novo design of a nanopore for single-molecule detection that incorporates a β-hairpin peptide von Shimizu, Keisuke, Mijiddorj, Batsaikhan, Usami, Masataka, Mizoguchi, Ikuro, Yoshida, Shuhei, Akayama, Shiori, Hamada, Yoshio, Ohyama, Akifumi, Usui, Kenji, Kawamura, Izuru, Kawano, Ryuji

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New directions for protease inhibitors directed drug discovery von Hamada, Yoshio, Kiso, Yoshiaki

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Recent progress in prodrug design strategies based on generally applicable modifications von Hamada, Yoshio

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Notch signaling maintains Leydig progenitor cells in the mouse testis von Tang, Hao, Brennan, Jennifer, Karl, Jeannie, Hamada, Yoshio, Raetzman, Lori, Capel, Blanche

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Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2 von Kokubo, Hiroki, Tomita-Miyagawa, Sachiko, Hamada, Yoshio, Saga, Yumiko

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Mass Spectrometry-Based Solid Phase Peptide Reaction Assay for Detecting Allergenicity Using an Immobilized Peptide-Conjugating Photo-Cleavable Linker von Miyazaki, Hiroshi, Samejima, Yasutaka, Iwata, Kazuya, Minamino, Yuuki, Hikida, Shinya, Ariumi, Hideto, Ikeda, Hidefumi, Hamada, Yoshio, Yamashita, Kunihiko, Usui, Kenji

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Notch2 Is Preferentially Expressed in Mature B Cells and Indispensable for Marginal Zone B Lineage Development von Saito, Toshiki, Chiba, Shigeru, Ichikawa, Motoshi, Kunisato, Atsushi, Asai, Takashi, Shimizu, Kiyoshi, Yamaguchi, Tomoyuki, Yamamoto, Go, Seo, Sachiko, Kumano, Keiki, Nakagami-Yamaguchi, Etsuko, Hamada, Yoshio, Aizawa, Shinichi, Hirai, Hisamaru

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DNA G-Wire Formation Using an Artificial Peptide is Controlled by Protease Activity von Usui, Kenji, Okada, Arisa, Sakashita, Shungo, Shimooka, Masayuki, Tsuruoka, Takaaki, Nakano, Shu-Ichi, Miyoshi, Daisuke, Mashima, Tsukasa, Katahira, Masato, Hamada, Yoshio

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Recent progress in the drug discovery of non-peptidic BACE1 inhibitors von Hamada, Yoshio, Kiso, Yoshiaki

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Novel prodrugs with a spontaneous cleavable guanidine moiety von Hamada, Yoshio

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Regulation of Marginal Zone B Cell Development by MINT, a Suppressor of Notch/RBP-J Signaling Pathway von Kuroda, Kazuki, Han, Hua, Tani, Shoichi, Tanigaki, Kenji, Tun, Tin, Furukawa, Takahisa, Taniguchi, Yoshihito, Kurooka, Hisanori, Hamada, Yoshio, Toyokuni, Shinya, Honjo, Tasuku

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A novel N-terminal degradation reaction of peptides via N-amidination von Hamada, Yoshio

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Synthesis of Peptide-Immobilized Magnetic Beads, and Peptide Reactivity Assay for Assessing Skin Sensitization Utilizing Chromophore von Miyazaki, Hiroshi, Takaishi, Hikaru, Ikeda, Hidefumi, Ariumi, Hideto, Hamada, Yoshio, Yamashita, Kunihiko, Usui, Kenji

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Tripeptidic BACE1 inhibitors devised by in-silico conformational structure-based design von Hamada, Yoshio, Tagad, Harichandra D., Nishimura, Yoshinori, Ishiura, Shoichi, Kiso, Yoshiaki

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Novel BACE1 inhibitors possessing a 5-nitroisophthalic scaffold at the P2 position von Hamada, Yoshio, Nakanishi, Tomoya, Suzuki, Kenji, Yamaguchi, Ryoji, Hamada, Takashi, Hidaka, Koushi, Ishiura, Shoichi, Kiso, Yoshiaki

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Structure–activity relationship study of BACE1 inhibitors possessing a chelidonic or 2,6-pyridinedicarboxylic scaffold at the P2 position von Hamada, Yoshio, Suzuki, Kenji, Nakanishi, Tomoya, Sarma, Diganta, Ohta, Hiroko, Yamaguchi, Ryoji, Yamasaki, Moe, Hidaka, Koushi, Ishiura, Shoichi, Kiso, Yoshiaki

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Combination of Non-natural d-Amino Acid Derivatives and Allophenylnorstatine−Dimethylthioproline Scaffold in HIV Protease Inhibitors Have High Efficacy in Mutant HIV von Nakatani, Shingo, Hidaka, Koushi, Ami, Ei’ichi, Nakahara, Koichiro, Sato, Akihiko, Nguyen, Jeffrey-Tri, Hamada, Yoshio, Hori, Yasuko, Ohnishi, Nobuyuki, Nagai, Akinori, Kimura, Tooru, Hayashi, Yoshio, Kiso, Yoshiaki

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Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality von Hamada, Y, Kadokawa, Y, Okabe, M, Ikawa, M, Coleman, J R, Tsujimoto, Y

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Design of Potent Aspartic Protease Inhibitors to Treat Various Diseases von Nguyen, Jeffrey-Tri, Hamada, Yoshio, Kimura, Tooru, Kiso, Yoshiaki

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Functional Diversity among Notch1, Notch2, and Notch3 Receptors von Shimizu, Kiyoshi, Chiba, Shigeru, Saito, Toshiki, Kumano, Keiki, Hamada, Yoshio, Hirai, Hisamaru

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