Vimentin filaments support extension of tubulin-based microtentacles in detached breast tumor cells von Whipple, Rebecca A, Balzer, Eric M, Cho, Edward H, Matrone, Michael A, Yoon, Jennifer R, Martin, Stuart S

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Epithelial-to-Mesenchymal Transition Promotes Tubulin Detyrosination and Microtentacles that Enhance Endothelial Engagement von WHIPPLE, Rebecca A, MATRONE, Michael A, CHO, Edward H, BALZER, Eric M, VITOLO, Michele I, YOON, Jennifer R, IOFFE, Olga B, TUTTLE, Kimberly C, JING YANG, MARTIN, Stuart S

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Local anesthetics inhibit kinesin motility and microtentacle protrusions in human epithelial and breast tumor cells von Yoon, Jennifer R., Whipple, Rebecca A., Balzer, Eric M., Cho, Edward H., Matrone, Michael A., Peckham, Michelle, Martin, Stuart S.

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The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence von Thompson, Keyata N, Whipple, Rebecca A, Yoon, Jennifer R, Lipsky, Michael, Charpentier, Monica S, Boggs, Amanda E, Chakrabarti, Kristi R, Bhandary, Lekhana, Hessler, Lindsay K, Martin, Stuart S, Vitolo, Michele I

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Metastatic breast tumors express increased tau, which promotes microtentacle formation and the reattachment of detached breast tumor cells von Matrone, M A, Whipple, R A, Thompson, K, Cho, E H, Vitolo, M I, Balzer, E M, Yoon, J R, Ioffe, O B, Tuttle, K C, Tan, M, Martin, S S

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Loss of PTEN induces microtentacles through PI3K-independent activation of cofilin von Vitolo, M I, Boggs, A E, Whipple, R A, Yoon, J R, Thompson, K, Matrone, M A, Cho, E H, Balzer, E M, Martin, S S

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Abstract 2161: Activation of the MAPK pathway in combination with PTEN loss leads to aggressive primary tumor formation von Thompson, Keyata N., Whipple, Rebecca A., Yoon, Jennifer R., Charpentier, Monica S., Boggs, Amanda E., Bhandary, Lekhana, Chakrabarti, Kristi R., Martin, Stuart S., Vitolo, Michele I.

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Abstract 3122: PTEN loss disrupts the actin cortex to promote tubulin microtentacle formation and increased metastatic potential von Vitolo, Michele I., Boggs, Amanda E., Thompson, Keyata, Whipple, Rebecca A., Yoon, Jennifer R., Slovic, Jana, Charpentier, Monica S., Matrone, Michael A., Martin, Stuart S.

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Abstract 1123: PTEN loss increases efficiency of breast tumor metastasis von Vitolo, Michele I., Thompson, Keyata, Whipple-Bettes, Rebecca A., Matrone, Michael A., Yoon, Jennifer R., Balzer, Eric M., Cho, Edward H., Martin, Stuart S.

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Abstract 1464: EMT-induced tubulin detyrosination can be inhibited with parthenolide, reducing microtentacles and the lung retention of circulating breast tumor cells von Whipple, Rebecca A., Matrone, Michael A., Cho, Edward H., Balzer, Eric M., Tuttle, Kimberly C., Vitolo, Michele I., Yoon, Jennifer R., Ioffe, Olga B., Yang, Jing, Martin, Stuart S.

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Patient safety after implementation of a coproduced family centered communication programme: multicenter before and after intervention study von Khan, Alisa, Spector, Nancy D, Baird, Jennifer D, Ashland, Michele, Starmer, Amy J, Rosenbluth, Glenn, Garcia, Briana M, Litterer, Katherine P, Rogers, Jayne E, Dalal, Anuj K, Lipsitz, Stuart, Yoon, Catherine S, Zigmont, Katherine R, Guiot, Amy, O'Toole, Jennifer K, Patel, Aarti, Bismilla, Zia, Coffey, Maitreya, Langrish, Kate, Blankenburg, Rebecca L, Destino, Lauren A, Everhart, Jennifer L, Good, Brian P, Kocolas, Irene, Srivastava, Rajendu, Calaman, Sharon, Cray, Sharon, Kuzma, Nicholas, Lewis, Kheyandra, Thompson, E Douglas, Hepps, Jennifer H, Lopreiato, Joseph O, Yu, Clifton E, Haskell, Helen, Kruvand, Elizabeth, Micalizzi, Dale A, Alvarado-Little, Wilma, Dreyer, Benard P, Yin, H Shonna, Subramony, Anupama, Patel, Shilpa J, Sectish, Theodore C, West, Daniel C, Landrigan, Christopher P

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De Novo Gene Disruptions in Children on the Autistic Spectrum von Iossifov, Ivan, Ronemus, Michael, Levy, Dan, Wang, Zihua, Hakker, Inessa, Rosenbaum, Julie, Yamrom, Boris, Lee, Yoon-ha, Narzisi, Giuseppe, Leotta, Anthony, Kendall, Jude, Grabowska, Ewa, Ma, Beicong, Marks, Steven, Rodgers, Linda, Stepansky, Asya, Troge, Jennifer, Andrews, Peter, Bekritsky, Mitchell, Pradhan, Kith, Ghiban, Elena, Kramer, Melissa, Parla, Jennifer, Demeter, Ryan, Fulton, Lucinda L., Fulton, Robert S., Magrini, Vincent J., Ye, Kenny, Darnell, Jennifer C., Darnell, Robert B., Mardis, Elaine R., Wilson, Richard K., Schatz, Michael C., McCombie, W. Richard, Wigler, Michael

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A mass spectrometric-derived cell surface protein atlas von Bausch-Fluck, Damaris, Hofmann, Andreas, Bock, Thomas, Frei, Andreas P, Cerciello, Ferdinando, Jacobs, Andrea, Moest, Hansjoerg, Omasits, Ulrich, Gundry, Rebekah L, Yoon, Charles, Schiess, Ralph, Schmidt, Alexander, Mirkowska, Paulina, Härtlová, Anetta, Van Eyk, Jennifer E, Bourquin, Jean-Pierre, Aebersold, Ruedi, Boheler, Kenneth R, Zandstra, Peter, Wollscheid, Bernd

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HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design von Bricault, Christine A., Yusim, Karina, Seaman, Michael S., Yoon, Hyejin, Theiler, James, Giorgi, Elena E., Wagh, Kshitij, Theiler, Maxwell, Hraber, Peter, Macke, Jennifer P., Kreider, Edward F., Learn, Gerald H., Hahn, Beatrice H., Scheid, Johannes F., Kovacs, James M., Shields, Jennifer L., Lavine, Christy L., Ghantous, Fadi, Rist, Michael, Bayne, Madeleine G., Neubauer, George H., McMahan, Katherine, Peng, Hanqin, Chéneau, Coraline, Jones, Jennifer J., Zeng, Jie, Ochsenbauer, Christina, Nkolola, Joseph P., Stephenson, Kathryn E., Chen, Bing, Gnanakaran, S., Bonsignori, Mattia, Williams, LaTonya D., Haynes, Barton F., Doria-Rose, Nicole, Mascola, John R., Montefiori, David C., Barouch, Dan H., Korber, Bette

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Adaptation and conservation insights from the koala genome von Johnson, Rebecca N., O’Meally, Denis, Chen, Zhiliang, Etherington, Graham J., Ho, Simon Y. W., Nash, Will J., Grueber, Catherine E., Cheng, Yuanyuan, Whittington, Camilla M., Dennison, Siobhan, Peel, Emma, Haerty, Wilfried, O’Neill, Rachel J., Colgan, Don, Russell, Tonia L., Alquezar-Planas, David E., Attenbrow, Val, Bragg, Jason G., Brandies, Parice A., Chong, Amanda Yoon-Yee, Deakin, Janine E., Di Palma, Federica, Duda, Zachary, Eldridge, Mark D. B., Ewart, Kyle M., Hogg, Carolyn J., Frankham, Greta J., Georges, Arthur, Gillett, Amber K., Govendir, Merran, Greenwood, Alex D., Hayakawa, Takashi, Helgen, Kristofer M., Hobbs, Matthew, Holleley, Clare E., Heider, Thomas N., Jones, Elizabeth A., King, Andrew, Madden, Danielle, Graves, Jennifer A. Marshall, Morris, Katrina M., Neaves, Linda E., Patel, Hardip R., Polkinghorne, Adam, Renfree, Marilyn B., Robin, Charles, Salinas, Ryan, Tsangaras, Kyriakos, Waters, Paul D., Waters, Shafagh A., Wright, Belinda, Wilkins, Marc R., Timms, Peter, Belov, Katherine

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Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization von So, Jae Young, Skrypek, Nicolas, Yang, Howard H., Merchant, Anand S., Nelson, George W., Chen, Wei-Dong, Ishii, Hiroki, Chen, Jennifer M., Hu, Gangqing, Achyut, Bhagelu R., Yoon, Esther C., Han, Liying, Huang, Chuanshu, Cam, Margaret C., Zhao, Keji, Lee, Maxwell P., Yang, Li

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The novel AKT inhibitor afuresertib shows favorable safety, pharmacokinetics, and clinical activity in multiple myeloma von Spencer, Andrew, Yoon, Sung-Soo, Harrison, Simon J., Morris, Shannon R., Smith, Deborah A., Brigandi, Richard A., Gauvin, Jennifer, Kumar, Rakesh, Opalinska, Joanna B., Chen, Christine

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COVID‐19 vaccinated children, adolescents, and young adults with acute lymphoblastic leukemia show spike reactive antibodies and multifunctional T‐cells von Parker, Rebecca S., Le, Justin, Villa, Miguel, Luong, Annie, Lin, Tsen Yin, Lee, Yesun, Doan, Andrew, Aguayo‐Hiraldo, Paibel, Pannaraj, Pia S., Yoon, Seon‐Jae, Wallace, William Dean, Armstrong, April, O'Gorman, Maurice R., Bard, Jennifer Dien, Parekh, Chintan

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Multi-Institutional Phase II Study of High-Dose Hypofractionated Proton Beam Therapy in Patients With Localized, Unresectable Hepatocellular Carcinoma and Intrahepatic Cholangiocar... von Hong, Theodore S, Wo, Jennifer Y, Yeap, Beow Y, Ben-Josef, Edgar, McDonnell, Erin I, Blaszkowsky, Lawrence S, Kwak, Eunice L, Allen, Jill N, Clark, Jeffrey W, Goyal, Lipika, Murphy, Janet E, Javle, Milind M, Wolfgang, John A, Drapek, Lorraine C, Arellano, Ronald S, Mamon, Harvey J, Mullen, John T, Yoon, Sam S, Tanabe, Kenneth K, Ferrone, Cristina R, Ryan, David P, DeLaney, Thomas F, Crane, Christopher H, Zhu, Andrew X

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Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models von Stockslager, Max A., Malinowski, Seth, Touat, Mehdi, Yoon, Jennifer C., Geduldig, Jack, Mirza, Mahnoor, Kim, Annette S., Wen, Patrick Y., Chow, Kin-Hoe, Ligon, Keith L., Manalis, Scott R.

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