Mitochondrial metabolism promotes adaptation to proteotoxic stress von Tsvetkov, Peter, Detappe, Alexandre, Cai, Kai, Keys, Heather R., Brune, Zarina, Ying, Weiwen, Thiru, Prathapan, Reidy, Mairead, Kugener, Guillaume, Rossen, Jordan, Kocak, Mustafa, Kory, Nora, Tsherniak, Aviad, Santagata, Sandro, Whitesell, Luke, Ghobrial, Irene M., Markley, John L., Lindquist, Susan, Golub, Todd R.

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Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy von Ying, Weiwen, Du, Zhenjian, Sun, Lijun, Foley, Kevin P, Proia, David A, Blackman, Ronald K, Zhou, Dan, Inoue, Takayo, Tatsuta, Noriaki, Sang, Jim, Ye, Shuxia, Acquaviva, Jamie, Ogawa, Luisa Shin, Wada, Yumiko, Barsoum, James, Koya, Keizo

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A rat retinal damage model predicts for potential clinical visual disturbances induced by Hsp90 inhibitors von Zhou, Dan, Liu, Yuan, Ye, Josephine, Ying, Weiwen, Ogawa, Luisa Shin, Inoue, Takayo, Tatsuta, Noriaki, Wada, Yumiko, Koya, Keizo, Huang, Qin, Bates, Richard C., Sonderfan, Andrew J.

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Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in In Vitro and In Vivo Models of Non―Small Cell Lung Cancer von SHIMAMURA, Takeshi, PERERA, Samanthi A, SINHA, Papiya, CAREY, Christopher D, BORGMAN, Christa L, JIMENEZ, John-Paul, MEYERSON, Matthew, WEIWEN YING, BARSOUM, James, WONG, Kwok-Kin, SHAPIRO, Geoffrey I, FOLEY, Kevin P, JIM SANG, RODIG, Scott J, INOUE, Takayo, LIANG CHEN, DANAN LI, CARRETERO, Julian, LI, Yu-Chen

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A well-circumscribed border with peripheral Doppler signal in sonographic image distinguishes epithelioid trophoblastic tumor from other gestational trophoblastic neoplasms von Qin, Jiale, Ying, Weiwen, Cheng, Xiaodong, Wu, Xiaodong, Lu, Bingjian, Liang, Yun, Wang, Xinyu, Wan, Xiaoyun, Xie, Xing, Lu, Weiguo

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Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease von Seeger-Nukpezah, Tamina, Proia, David A., Egleston, Brian L., Nikonova, Anna S., Kent, Tatiana, Cai, Kathy Q., Hensley, Harvey H., Ying, Weiwen, Chimmanamada, Dinesh, Serebriiskii, Ilya G., Golemis, Erica A.

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Indole- and indolizine-glyoxylamides displaying cytotoxicity against multidrug resistant cancer cell lines von James, David A., Koya, Keizo, Li, Hao, Liang, Guiqing, Xia, Zhiqiang, Ying, Weiwen, Wu, Yaming, Sun, Lijun

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The novel HSP90 inhibitor STA-9090 exhibits activity against Kit-dependent and -independent malignant mast cell tumors von Lin, Tzu-Yin, Bear, Misty, Du, Zhenjian, Foley, Kevin P, Ying, Weiwen, Barsoum, James, London, Cheryl

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Author Correction: Mitochondrial metabolism promotes adaptation to proteotoxic stress von Tsvetkov, Peter, Detappe, Alexandre, Cai, Kai, Keys, Heather R., Brune, Zarina, Ying, Weiwen, Thiru, Prathapan, Reidy, Mairead, Kugener, Guillaume, Rossen, Jordan, Kocak, Mustafa, Kory, Nora, Tsherniak, Aviad, Santagata, Sandro, Whitesell, Luke, Ghobrial, Irene M., Markley, John L., Lindquist, Susan, Golub, Todd R.

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The novel HSP90 inhibitor STA‐1474 exhibits biologic activity against osteosarcoma cell lines von McCleese, Jennifer K., Bear, Misty D., Fossey, Stacey L., Mihalek, Robert M., Foley, Kevin P., Ying, Weiwen, Barsoum, James, London, Cheryl A.

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Phase I evaluation of STA-1474, a prodrug of the novel HSP90 inhibitor ganetespib, in dogs with spontaneous cancer von London, Cheryl A, Bear, Misty D, McCleese, Jennifer, Foley, Kevin P, Paalangara, Reji, Inoue, Takayo, Ying, Weiwen, Barsoum, James

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Targeting heat shock protein 90 for the treatment of malignant pheochromocytoma von Giubellino, Alessio, Sourbier, Carole, Lee, Min-Jung, Scroggins, Brad, Bullova, Petra, Landau, Michael, Ying, Weiwen, Neckers, Len, Trepel, Jane B, Pacak, Karel

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The HSP90 Inhibitor Ganetespib Alleviates Disease Progression and Augments Intermittent Cyclophosphamide Therapy in the MRL/lpr Mouse Model of Systemic Lupus Erythematosus von Liu, Yuan, Ye, Josephine, Shin Ogawa, Luisa, Inoue, Takayo, Huang, Qin, Chu, John, Bates, Richard C, Ying, Weiwen, Sonderfan, Andrew J, Rao, Patricia E, Zhou, Dan

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Heat shock protein 90 regulates the expression of Wilms tumor 1 protein in myeloid leukemias von Bansal, Hima, Bansal, Sanjay, Rao, Manjeet, Foley, Kevin P., Sang, Jim, Proia, David A., Blackman, Ronald K., Ying, Weiwen, Barsoum, James, Baer, Maria R., Kelly, Kevin, Swords, Ronan, Tomlinson, Gail E., Battiwalla, Minoo, Giles, Francis J., Lee, Kelvin P., Padmanabhan, Swaminathan

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Interaction of small molecule inhibitors of HIV-1 entry with CCR5 von Seibert, Christoph, Ying, Weiwen, Gavrilov, Svetlana, Tsamis, Fotini, Kuhmann, Shawn E., Palani, Anandan, Tagat, Jayaram R., Clader, John W., McCombie, Stuart W., Baroudy, Bahige M., Smith, Steven O., Dragic, Tatjana, Moore, John P., Sakmar, Thomas P.

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A Binding Pocket for a Small Molecule Inhibitor of HIV-1 Entry within the Transmembrane Helices of CCR5 von Dragic, Tatjana, Trkola, Alexandra, Daniah A. D. Thompson, Cormier, Emmanuel G., Kajumo, Francis A., Maxwell, Elizabeth, Lin, Steven W., Ying, Weiwen, Smith, Steven O., Sakmar, Thomas P., Moore, John P.

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Conjugated indole-imidazole derivatives displaying cytotoxicity against multidrug resistant cancer cell lines von James, David A., Koya, Keizo, Li, Hao, Chen, Shoujun, Xia, Zhiqiang, Ying, Weiwen, Wu, Yaming, Sun, Lijun

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Implications of Threonine Hydrogen Bonding in the Glycophorin A Transmembrane Helix Dimer von Smith, Steven O., Eilers, Markus, Song, David, Crocker, Evan, Ying, Weiwen, Groesbeek, Michel, Metz, Guenter, Ziliox, Martine, Aimoto, Saburo

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Abstract 971: Chaperone-mediated protein degradation (CHAMP): A novel technology for tumor-targeted protein degradation von Foley, Kevin P., Ye, Long, Wang, Mingkai, Ying, Chenghao, Yin, Wei, Zhang, Lingjie, Ying, Weiwen

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The cytoplasmic end of transmembrane domain 3 regulates the activity of the Saccharomyces cerevisiae G-protein-coupled alpha-factor receptor von Parrish, William, Eilers, Markus, Ying, Weiwen, Konopka, James B

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