MDM2-Recruiting PROTAC Offers Superior, Synergistic Antiproliferative Activity via Simultaneous Degradation of BRD4 and Stabilization of p53 von Hines, John, Lartigue, Schan, Dong, Hanqing, Qian, Yimin, Crews, Craig M

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PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer von Raina, Kanak, Lu, Jing, Qian, Yimin, Altieri, Martha, Gordon, Deborah, Rossi, Ann Marie K., Wang, Jing, Chen, Xin, Dong, Hanqing, Siu, Kam, Winkler, James D., Crew, Andrew P., Crews, Craig M., Coleman, Kevin G.

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Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1 von Crew, Andrew P, Raina, Kanak, Dong, Hanqing, Qian, Yimin, Wang, Jing, Vigil, Dominico, Serebrenik, Yevgeniy V, Hamman, Brian D, Morgan, Alicia, Ferraro, Caterina, Siu, Kam, Neklesa, Taavi K, Winkler, James D, Coleman, Kevin G, Crews, Craig M

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RUNX1-targeted therapy for AML expressing somatic or germline mutation in RUNX1 von Mill, Christopher P., Fiskus, Warren, DiNardo, Courtney D., Qian, Yimin, Raina, Kanak, Rajapakshe, Kimal, Perera, Dimuthu, Coarfa, Cristian, Kadia, Tapan M., Khoury, Joseph D., Saenz, Dyana T., Saenz, David N., Illendula, Anuradha, Takahashi, Koichi, Kornblau, Steven M., Green, Michael R., Futreal, Andrew P., Bushweller, John H., Crews, Craig M., Bhalla, Kapil N.

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Recommending the most ecological sustainable option for the generation of tidal power in the Severn Estuary von yimin, Qian, Jie, Jin

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A Data-Driven Vulnerability Evaluation Method in Grid Edge Based on Random Matrix Theory Indicators von Ding, Kai, Qian, Yimin, Wang, Yi, Hu, Pan, Wang, Bo

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Fast Open Circuit Voltage Estimation of Lithium-Ion Batteries Using a Relaxation Model and Genetic Algorithm von Qian, Yimin, Zheng, Jian, Ding, Kai, Zhang, Hui, Chen, Qiao, Wang, Bei, Wang, Yi, Huang, Zengrui

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A 90-day Sub-chronic Oral Toxicity Assessment of Mulberry Extract in Sprague Dawley Rats von Hong, Min, Lu, Min, Qian, Yimin, Wei, Liping, Zhang, Yaqun, Pan, Xueying, Li, Hua, Chen, Huaying, Tang, Naping

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Flexible Resources Planning for Bulk Energy System With High Penetration of Renewable Energy Based on Bash Game von Hu, Pan, Zixun, Cao, Chen, Hongkun, Yi, Wang, Ye, Chang, Qiao, Chen, Yimin, Qian

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Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4 von Lu, Jing, Qian, Yimin, Altieri, Martha, Dong, Hanqing, Wang, Jing, Raina, Kanak, Hines, John, Winkler, James D., Crew, Andrew P., Coleman, Kevin, Crews, Craig M.

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A Comprehensive Assessment of Drought and Climate Change von Qian, yimin, Yao, Shuiping, Yan, Kun, Tang, Wenjia

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Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-ras prenylation but each alone is sufficient to suppress human tumor... von SUN, J, YIMIN QIAN, HAMILTON, A. D, SEBTI, S. M

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Discovery of 1-arylcarbonyl-6,7-dimethoxyisoquinoline derivatives as glutamine fructose-6-phosphate amidotransferase (GFAT) inhibitors von Qian, Yimin, Ahmad, Mushtaq, Chen, Shaoqing, Gillespie, Paul, Le, Nam, Mennona, Frank, Mischke, Steven, So, Sung-Sau, Wang, Hong, Burghardt, Charles, Tannu, Shahid, Conde-Knape, Karin, Kochan, Jarema, Bolin, David

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Comparing the differential effects of LPA on the barrier function of human pulmonary endothelial cells von Ren, Yonglin, Guo, Liang, Tang, Xiaoyan, Apparsundaram, Subramaniam, Kitson, Christopher, Deguzman, Jeremy, Fuentes, Maria E., Coyle, Luke, Majmudar, Rupal, Allard, John, Truitt, Theresa, Hamid, Rachid, Chen, Yun, Qian, Yimin, Budd, David C.

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Discovery and optimization of 2-phenyloxazole derivatives as diacylglycerol acyltransferase-1 inhibitors von Yun, Weiya, Ahmad, Mushtaq, Chen, Yingsi, Gillespie, Paul, Conde-Knape, Karin, Kazmer, Sonja, Li, Shiming, Qian, Yimin, Taub, Rebecca, Wertheimer, Stanley J., Whittard, Toni, Bolin, David

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Antitumor efficacy of a novel class of non-thiol-containing peptidomimetic inhibitors of farnesyltransferase and geranylgeranyltransferase I : Combination therapy with the cytotoxi... von JIAZHI SUN, BLASKOVICH, M. A, KNOWLES, D, YIMIN QIAN, OHKANDA, J, BAILEY, R. D, HAMILTON, A. D, SEBTI, S. M

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Integration of conflict resolution and positive emotions: Electrophysiological evidence von Pan, Fada, Ou, Yuhong, Sun, Hui, Qian, Yimin

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Sinensetin interferes with Staphylococcus aureus infections by targeting staphylocoagulase and improves infection survival rates in mouse model of pneumonia von Ge, Bin, Hu, Chunjie, Qian, Yimin, Tang, Yating, Zhang, Qiuyue, Jiang, Shuang, Mu, Zongyi, Zhang, Maoyun

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Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I i... von LERNER, E. C, ZHANG, T.-T, KNOWLES, D. B, QIAN, Y, HAMILTON, A. D, SEBTI, S. M

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Inhibiting ras prenylation increases the radiosensitivity of human tumor cell lines with activating mutations of ras oncogenes von BERNHARD, E. J, MCKENNA, W. G, HAMILTON, A. D, SEBTI, S. M, YIMIN QIAN, JUNMIN WU, MUSCHEL, R. J

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