Cyclodextrin induces calcium-dependent lysosomal exocytosis von Chen, Fannie W, Li, Chunlei, Ioannou, Yiannis A

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Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth von Sangodkar, Jaya, Perl, Abbey, Tohme, Rita, Kiselar, Janna, Kastrinsky, David B, Zaware, Nilesh, Izadmehr, Sudeh, Mazhar, Sahar, Wiredja, Danica D, O'Connor, Caitlin M, Hoon, Divya, Dhawan, Neil S, Schlatzer, Daniela, Yao, Shen, Leonard, Daniel, Borczuk, Alain C, Gokulrangan, Giridharan, Wang, Lifu, Svenson, Elena, Farrington, Caroline C, Yuan, Eric, Avelar, Rita A, Stachnik, Agnes, Smith, Blake, Gidwani, Vickram, Giannini, Heather M, McQuaid, Daniel, McClinch, Kimberly, Wang, Zhizhi, Levine, Alice C, Sears, Rosalie C, Chen, Edward Y, Duan, Qiaonan, Datt, Manish, Haider, Shozeb, Ma'ayan, Avi, DiFeo, Analisa, Sharma, Neelesh, Galsky, Matthew D, Brautigan, David L, Ioannou, Yiannis A, Xu, Wenqing, Chance, Mark R, Ohlmeyer, Michael, Narla, Goutham

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PKC activation in Niemann pick C1 cells restores subcellular cholesterol transport von Tamari, Farshad, Chen, Fannie W, Li, Chunlei, Chaudhari, Jagrutiben, Ioannou, Yiannis A

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Sex and Pubertal Differences in the Type 1 Interferon Pathway Associate With Both X Chromosome Number and Serum Sex Hormone Concentration von Webb, Kate, Peckham, Hannah, Radziszewska, Anna, Menon, Madhvi, Oliveri, Paola, Simpson, Fraser, Deakin, Claire T, Lee, Sophie, Ciurtin, Coziana, Butler, Gary, Wedderburn, Lucy R, Ioannou, Yiannis

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Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe von Temel, Ryan E, Tang, Weiqing, Ma, Yinyan, Rudel, Lawrence L, Willingham, Mark C, Ioannou, Yiannis A, Davies, Joanna P, Nilsson, Lisa-Mari, Yu, Liqing

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The Differences Between Childhood and Adult Onset Antiphospholipid Syndrome von Wincup, Chris, Ioannou, Yiannis

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Measuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome von Pericleous, Charis, Ferreira, Isabel, Borghi, Orietta, Pregnolato, Francesca, McDonnell, Thomas, Garza-Garcia, Acely, Driscoll, Paul, Pierangeli, Silvia, Isenberg, David, Ioannou, Yiannis, Giles, Ian, Meroni, Pier Luigi, Rahman, Anisur

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Inactivation of NPC1L1 Causes Multiple Lipid Transport Defects and Protects against Diet-induced Hypercholesterolemia von Davies, Joanna P., Scott, Catherine, Oishi, Kimihiko, Liapis, Anastasia, Ioannou, Yiannis A.

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MLN64 transport to the late endosome is regulated by binding to 14-3-3 via a non-canonical binding site von Liapis, Anastasia, Chen, Fannie W, Davies, Joanna P, Wang, Rong, Ioannou, Yiannis A

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Incidence of Antiphospholipid Syndrome: Is Estimation Currently Possible? von Ioannou, Yiannis, Beukelman, Timothy, Murray, Miranda, Erkan, Doruk

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How we diagnose the antiphospholipid syndrome von Giannakopoulos, Bill, Passam, Freda, Ioannou, Yiannis, Krilis, Steven A.

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Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer von McClinch, Kimberly, Avelar, Rita A, Callejas, David, Izadmehr, Sudeh, Wiredja, Danica, Perl, Abbey, Sangodkar, Jaya, Kastrinsky, David B, Schlatzer, Daniela, Cooper, Maxwell, Kiselar, Janna, Stachnik, Agnes, Yao, Shen, Hoon, Divya, McQuaid, Daniel, Zaware, Nilesh, Gong, Yixuan, Brautigan, David L, Plymate, Stephen R, Sprenger, Cynthia C T, Oh, William K, Levine, Alice C, Kirschenbaum, Alexander, Sfakianos, John P, Sears, Rosalie, DiFeo, Analisa, Ioannou, Yiannis, Ohlmeyer, Michael, Narla, Goutham, Galsky, Matthew D

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An “Exacerbate-reverse” Strategy in Yeast Identifies Histone Deacetylase Inhibition as a Correction for Cholesterol and Sphingolipid Transport Defects in Human Niemann-Pick Type C... von Munkacsi, Andrew B., Chen, Fannie W., Brinkman, Matthew A., Higaki, Katsumi, Gutiérrez, Giselle Domínguez, Chaudhari, Jagruti, Layer, Jacob V., Tong, Amy, Bard, Martin, Boone, Charles, Ioannou, Yiannis A., Sturley, Stephen L.

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CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α von Piper, Christopher J. M., Wilkinson, Meredyth G. Ll, Deakin, Claire T., Otto, Georg W., Dowle, Stefanie, Duurland, Chantal L., Adams, Stuart, Marasco, Emiliano, Rosser, Elizabeth C., Radziszewska, Anna, Carsetti, Rita, Ioannou, Yiannis, Beales, Philip L., Kelberman, Daniel, Isenberg, David A., Mauri, Claudia, Nistala, Kiran, Wedderburn, Lucy R.

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Naturally occurring free thiols within β2-glycoprotein I in vivo: nitrosylation, redox modification by endothelial cells, and regulation of oxidative stress–induced cell injury von Ioannou, Yiannis, Zhang, Jing-Yun, Passam, Freda H., Rahgozar, Soheila, Qi, Jian Cheng, Giannakopoulos, Bill, Qi, Miao, Yu, Pei, Yu, Demin M., Hogg, Philip J., Krilis, Steven A.

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Transmembrane Molecular Pump Activity of Niemann-Pick C1 Protein von Davies, Joanna P., Chen, Fannie W., Ioannou, Yiannis A.

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Hydroxychloroquine Protects against Cardiac Ischaemia/Reperfusion Injury In Vivo via Enhancement of ERK1/2 Phosphorylation von Bourke, Lauren, McCormick, James, Taylor, Valerie, Pericleous, Charis, Blanchet, Benoit, Costedoat-Chalumeau, Nathalie, Stuckey, Daniel, Lythgoe, Mark F, Stephanou, Anastasis, Ioannou, Yiannis

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Pubertal timing after neonatal diethylstilbestrol exposure in female rats: Neuroendocrine vs peripheral effects and additive role of prenatal food restriction von Franssen, Delphine, Ioannou, Yiannis S., Alvarez-real, Alexandra, Gerard, Arlette, Mueller, Johanna K., Heger, Sabine, Bourguignon, Jean-Pierre, Parent, Anne-Simone

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Oxidation of β2-glycoprotein I associates with IgG antibodies to domain I in patients with antiphospholipid syndrome von Raimondo, Maria Gabriella, Pericleous, Charis, Radziszewska, Anna, Borghi, Maria Orietta, Pierangeli, Silvia, Meroni, Pier Luigi, Giles, Ian, Rahman, Anisur, Ioannou, Yiannis

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Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction von Chen, Fannie W., Davies, Joanna P., Calvo, Raul, Chaudhari, Jagruti, Dolios, Georgia, Taylor, Mercedes K., Patnaik, Samarjit, Dehdashti, Jean, Mull, Rebecca, Dranchack, Patricia, Wang, Amy, Xu, Xin, Hughes, Emma, Southall, Noel, Ferrer, Marc, Wang, Rong, Marugan, Juan J., Ioannou, Yiannis A.

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