The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins von Deora, Vandana, Lee, John D., Albornoz, Eduardo A., McAlary, Luke, Jagaraj, Cyril J., Robertson, Avril A. B., Atkin, Julie D., Cooper, Matthew A., Schroder, Kate, Yerbury, Justin J., Gordon, Richard, Woodruff, Trent M.

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Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis von McAlary, Luke, Plotkin, Steven S, Yerbury, Justin J, Cashman, Neil R

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Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms von Grad, Leslie I., Yerbury, Justin J., Turner, Bradley J., Guest, William C., Pokrishevsky, Edward, O'Neill, Megan A., Yanai, Anat, Silverman, Judith M., Zeineddine, Rafaa, Corcoran, Lisa, Kumita, Janet R., Luheshi, Leila M., Yousefi, Masoud, Coleman, Bradley M., Hill, Andrew F., Plotkin, Steven S., Mackenzie, Ian R., Cashman, Neil R.

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Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons von Svahn, Adam J., Don, Emily K., Badrock, Andrew P., Cole, Nicholas J., Graeber, Manuel B., Yerbury, Justin J., Chung, Roger, Morsch, Marco

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Extracellular chaperones and proteostasis von Wyatt, Amy R, Yerbury, Justin J, Ecroyd, Heath, Wilson, Mark R

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p62 overexpression induces TDP-43 cytoplasmic mislocalisation, aggregation and cleavage and neuronal death von Foster, A. D., Flynn, L. L., Cluning, C., Cheng, F., Davidson, J. M., Lee, A., Polain, N., Mejzini, R., Farrawell, N., Yerbury, J. J., Layfield, R., Akkari, P. A., Rea, S. L.

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A copper chaperone–mimetic polytherapy for SOD1-associated amyotrophic lateral sclerosis von McAlary, L., Shephard, V.K., Wright, G.S.A., Yerbury, J.J.

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The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation von Capper, Michael J., Wright, Gareth S. A., Barbieri, Letizia, Luchinat, Enrico, Mercatelli, Eleonora, McAlary, Luke, Yerbury, Justin J., O’Neill, Paul M., Antonyuk, Svetlana V., Banci, Lucia, Hasnain, S. Samar

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Strategies to promote the maturation of ALS-associated SOD1 mutants: small molecules return to the fold von McAlary, Luke, Yerbury, Justin

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The heat shock response in neurons and astroglia and its role in neurodegenerative diseases von San Gil, Rebecca, Ooi, Lezanne, Yerbury, Justin J, Ecroyd, Heath

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Tryptophan residue 32 in human Cu-Zn superoxide dismutase modulates prion-like propagation and strain selection von Crown, Anthony, McAlary, Luke, Fagerli, Eric, Brown, Hilda, Yerbury, Justin J, Galaleldeen, Ahmad, Cashman, Neil R, Borchelt, David R, Ayers, Jacob I

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P2X7 Receptor Activation Induces Reactive Oxygen Species Formation and Cell Death in Murine EOC13 Microglia von Bartlett, Rachael, Yerbury, Justin J., Sluyter, Ronald

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SOD1A4V aggregation alters ubiquitin homeostasis in a cell model of ALS von Farrawell, Natalie E., Lambert-Smith, Isabella, Mitchell, Kristen, McKenna, Jessie, McAlary, Luke, Ciryam, Prajwal, Vine, Kara L., Saunders, Darren N., Yerbury, Justin J.

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Disease Mechanisms in ALS: Misfolded SOD1 Transferred Through Exosome-Dependent and Exosome-Independent Pathways von Silverman, Judith M., Fernando, Sarah M., Grad, Leslie I., Hill, Andrew F., Turner, Bradley J., Yerbury, Justin J., Cashman, Neil R.

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High-content analysis of proteostasis capacity in cellular models of amyotrophic lateral sclerosis (ALS) von Lambert-Smith, Isabella A., Shephard, Victoria K., McAlary, Luke, Yerbury, Justin J., Saunders, Darren N.

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Disabled in academia: to be or not to be, that is the question von Yerbury, Justin J., Yerbury, Rachel M.

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Mutant Cu/Zn Superoxide Dismutase (A4V) Turnover Is Altered in Cells Containing Inclusions von Farrawell, Natalie E., Yerbury, Justin J.

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ANS Binding Reveals Common Features of Cytotoxic Amyloid Species von Bolognesi, Benedetta, Kumita, Janet R., Barros, Teresa P., Esbjorner, Elin K., Luheshi, Leila M., Crowther, Damian C., Wilson, Mark R., Dobson, Christopher M., Favrin, Giorgio, Yerbury, Justin J.

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Misfolding at the synapse: A role in amyotrophic lateral sclerosis pathogenesis? von Lum, Jeremy S., Yerbury, Justin J.

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Rapid flow cytometric measurement of protein inclusions and nuclear trafficking von Whiten, D. R., San Gil, R., McAlary, L., Yerbury, J. J., Ecroyd, H., Wilson, M. R.

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