METHODS AND SYSTEM FOR LOCATION-BASED TARGETED OFFERS VIA VEHICLE COMMUNICATION SYSTEM von IANNACE, Marianne, IYER, Prasad, V, YATES, Lisa, Helen, LOWERY, Patrick, SCHECHNER, Sheridan, Benjamin

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METHODS AND SYSTEM FOR LOCATION-BASED TARGETED OFFERS VIA VEHICLE COMMUNICATION SYSTEM von Lowery Patrick, Schechner Sheridan Benjamin, Iannace Marianne, Yates Lisa Helen, Iyer Prasad V

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Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production von Chen, Helen, Victor, A Kaitlyn, Klein, Jonathon, Tacer, Klementina Fon, Tai, Derek Jc, de Esch, Celine, Nuttle, Alexander, Temirov, Jamshid, Burnett, Lisa C, Rosenbaum, Michael, Zhang, Yiying, Ding, Li, Moresco, James J, Diedrich, Jolene K, Yates, 3rd, John R, Tillman, Heather S, Leibel, Rudolph L, Talkowski, Michael E, Billadeau, Daniel D, Reiter, Lawrence T, Potts, Patrick Ryan

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Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study von Halpin, Sophie, Donohue, Chloe, Ladhani, Shamez, Horby, Peter W, Docherty, Annemarie B, Semple, Malcolm G, Openshaw, Peter J M, Bach, Benjamin, Chand, Meera, Harrison, Ewen M, Hiscox, Julian A, Horby, Peter W, Klenerman, Paul, Law, Andrew, Moore, Shona C, Palmarini, Massimo, Russell, Clark D, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Thomson, Emma C, Oosthuyzen, Wilna, Norman, Lisa, Pius, Riinu, Mclean, Kenneth A, Saviciute, Egle, Leeming, Gary, Hendry, Ross, Greenhalf, William, Ahmed, Katie A, Asiimwe, Innocent G, Brennan, Benjamin, Catterall, Benjamin WA, Clark, Jordan J, Cole, Sarah, Cox, Helen, Elliott, Angela, Foster, Terry, Greenhalf, Willliam, Jones, Trevor R, Murphy, Ellen G, Small, Benjamin, Subramaniam, Krishanthi S, Tanianis, Jolanta, Trochu, Erwan, van Tonder, Libby, Wilcock, Eve, Agranoff, Daniel, Angus, Brian, Atkinson, Dougal, Barlow, Gavin, Barrett, Nicholas, Bassford, Christopher, Beadsworth, Michael, Best, Nicola, Burden, Tom, Chukkambotla, Srikanth, Cupitt, Jason, Dark, Paul, Dushianthan, Ahilanadan, Dyer, Tristan, Evans, Cariad, Fegan, Christopher, Finn, Adam, Fullerton, Duncan, Goldsmith, Arthur, Hardy, Elaine, Havalda, Peter, Holme, Anita, Kendall, Jason, Kerrison, Caroline, Larkin, Susan, Leiner, Tamas, Lillie, Patrick, MacNaughton, Emily, McCullough, Katherine, Moore, Elinoor, Morgan, Patrick, Morris, Craig, Nelson, Mark, Panchatsharam, Selva, Pintus, Stefania, Prout, Rachel, Rousseau, Guy, Ryan, Brendan, Saluja, Taranprit, Shanmuga, Prad, Sharma, Anil, Sizer, Jeremy, Smith, Richard, Snelson, Catherine, Spittle, Nick, Stambach, Tom, Tridente, Ascanio, Ustianowski, Andrew, Waddy, Sam, Whittaker, Paul, Williams, Martin, Wiselka, Martin, Young, Peter

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Mutation analysis of 24 known cancer genes in the NCI-60 cell line set von Ikediobi, Ogechi N, Davies, Helen, Bignell, Graham, Edkins, Sarah, Stevens, Claire, O'Meara, Sarah, Santarius, Thomas, Avis, Tim, Barthorpe, Syd, Brackenbury, Lisa, Buck, Gemma, Butler, Adam, Clements, Jody, Cole, Jennifer, Dicks, Ed, Forbes, Simon, Gray, Kristian, Halliday, Kelly, Harrison, Rachel, Hills, Katy, Hinton, Jonathan, Hunter, Chris, Jenkinson, Andy, Jones, David, Kosmidou, Vivienne, Lugg, Richard, Menzies, Andrew, Mironenko, Tatiana, Parker, Adrian, Perry, Janet, Raine, Keiran, Richardson, David, Shepherd, Rebecca, Small, Alex, Smith, Raffaella, Solomon, Helen, Stephens, Philip, Teague, Jon, Tofts, Calli, Varian, Jennifer, Webb, Tony, West, Sofie, Widaa, Sara, Yates, Andy, Reinhold, William, Weinstein, John N, Stratton, Michael R, Futreal, P Andrew, Wooster, Richard

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A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy von HUNTER, Chris, SMITH, Raffaella, O'MEARA, Sarah, PARKER, Adrian, AVIS, Tim, BARTHORPE, Syd, BRACKENBURY, Lisa, BUCK, Gemma, BUTLER, Adam, CLEMENTS, Jody, COLE, Jennifer, DICKS, Ed, CAHILL, Daniel P, FORBES, Simon, GORTON, Matthew, GRAY, Kristian, HALLIDAY, Kelly, HARRISON, Rachel, HILLS, Katy, HINTON, Jonathon, JENKINSON, Andy, JONES, David, KOSMIDOU, Vivienne, STEPHENS, Philip, LAMAN, Ross, LUGG, Richard, MENZIES, Andrew, PERRY, Janet, PETTY, Robert, RAINE, Keiran, RICHARDSON, David, SHEPHERD, Rebecca, SMALL, Alexandra, SOLOMON, Helen, STEVENS, Claire, TOFTS, Calli, VARIAN, Jennifer, WEST, Sofie, WIDAA, Sara, YATES, Andy, EASTON, Douglas F, RIGGINS, Gregory, ROY, Jennifer E, LEVINE, Kymberly K, MUELLER, Wolf, TEAGUE, Jon, BATCHELOR, Tracy T, LOUIS, David N, STRATTON, Michael R, FUTREAL, P. Andrew, WOOSTER, Richard, GREENMAN, Chris, EDKINS, Sarah, BIGNELL, Graham, DAVIES, Helen

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Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WH... von Bloom, Chloe I, Drake, Thomas M, Lipworth, Brian J, Johnston, Sebastian L, Nguyen-Van-Tam, Jonathan S, Carson, Gail, Semple, Malcolm G, Cullinan, Paul, Openshaw, Peter J M, Bach, Benjamin, Barclay, Wendy S, Chand, Meera, Fletcher, Tom, Khoo, Saye, Meynert, Alison M, Price, Nicholas, Robertson, David L, Sancho-Shimizu, Vanessa, Thomson, Emma C, Hardwick, Hayley, Oosthuyzen, Wilna, Pius, Riinu, Knight, Stephen R, Shaw, Catherine A, Marsh, Laura, Clohisey, Sara, Hendry, Ross, Scott-Brown, James, Shaw, Victoria, McDonald, Sara, Ahmed, Katie A., Booth, Laura, Catterall, Benjamin WA, Clarke, Emily A, Cooper, Louise, Davis, Christopher, Dincarslan, Oslem, Dunn, Chris, Evans, Anthony, Khandaker, Shadia, Lant, Suzannah, Lett, Lauren, McDonald, Sarah, McLauchlan, John, Penrice-Randal, Rebekah, Pilgrim, Jack, Wilcock, Eve, Carracedo, Alejandra Doce, Carlucci, Nicola, Holmes, Anthony, Agranoff, Daniel, Atkinson, Dougal, Barnass, Stella, Bassford, Christopher, Baxter, David, Beadsworth, Michael, Bothma, Pieter, Brittain-Long, Robin, Chambler, Duncan, Child, Jenny, Cupitt, Jason, Dark, Paul, Douthwaite, Sam, Dushianthan, Ahilanadan, Fullerton, Duncan, Hawcutt, Daniel B, Hormis, Anil, Kaliappan, Agilan, Kasipandian, Vidya, Kegg, Stephen, Kerslake, Ian, Koch, Oliver, Koshy, George, Laha, Shondipon, Limb, James, MacMahon, Michael, Matovu, Elijah, McEwen, Ruth, Mok, Quen, Mortimore, Katherine, Mpenge, Mbiye, Pais, Mark, Pepperell, Justin, Phull, Mandeep, Post, Frank, Reschreiter, Henrik, Roberts, Mark, Roberts, Devender, Rose, Alistair, Ryan, Brendan, Spittle, Nick, Thompson, Robert, Vuylsteke, Alan, Waddy, Sam, Whittaker, Paul, Whittington, Ashley, Wijesinghe, Meme, Wilson, Sarah, Wooton, Daniel G, Yates, Bryan

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Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders von BAXTER, E, SCOTT, L, CAMPBELL, P, EAST, C, FOUROUCLAS, N, SWANTON, S, VASSILIOU, G, BENCH, A, BOYD, E, CURTIN, N

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Intragenic ERBB2 kinase mutations in tumours von Stephens, Philip, Hunter, Chris, Bignell, Graham, Edkins, Sarah, Davies, Helen, Teague, Jon, Stevens, Claire, O'Meara, Sarah, Smith, Raffaella, Parker, Adrian, Barthorpe, Andy, Blow, Matthew, Brackenbury, Lisa, Butler, Adam, Clarke, Oliver, Cole, Jennifer, Dicks, Ed, Dike, Angus, Drozd, Anja, Edwards, Ken, Forbes, Simon, Foster, Rebecca, Gray, Kristian, Greenman, Chris, Halliday, Kelly, Hills, Katy, Kosmidou, Vivienne, Lugg, Richard, Menzies, Andy, Perry, Janet, Petty, Robert, Raine, Keiran, Ratford, Lewis, Shepherd, Rebecca, Small, Alexandra, Stephens, Yvonne, Tofts, Calli, Varian, Jennifer, West, Sofie, Widaa, Sara, Yates, Andrew, Brasseur, Francis, Cooper, Colin S., Flanagan, Adrienne M., Knowles, Margaret, Leung, Suet Y., Louis, David N., Looijenga, Leendert H. J., Malkowicz, Bruce, Pierotti, Marco A., Teh, Bin, Chenevix-Trench, Georgia, Weber, Barbara L., Yuen, Siu T., Harris, Grace, Goldstraw, Peter, Nicholson, Andrew G., Futreal, P. Andrew, Wooster, Richard, Stratton, Michael R.

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Development of a centralised national AED (automated external defibrillator) network across all ambulance services in the United Kingdom von O’Sullivan, Judy, Moore, Edward, Dunn, Simon, Tennant, Helen, Smith, Dexter, Black, Sarah, Yates, Sarah, Lawrence, Amelia, McManus, Madeline, Day, Emma, Miles, Martin, Irving, Steve, Hampshire, Sue, Thomas, Lynn, Henry, Nick, Bywater, Dave, Bradfield, Michael, Deakin, Charles D., Holmes, Simon, Leckey, Stephanie, Linker, Nick, Lloyd, Greg, Mark, Julian, MacInnes, Lisa, Walsh, Simon, Woods, George, Perkins, Gavin D.

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Interlaboratory variation in 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 is significantly improved if common calibration material is used von Yates, Alexandra Marie, Bowron, Ann, Calton, Lisa, Heynes, Joanne, Field, Helen, Rainbow, Sandra, Keevil, Brian

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The ENHANCES study: a randomised controlled trial of a nurse-led survivorship intervention for patients treated for head and neck cancer von Turner, Jane, Yates, Patsy, Kenny, Lizbeth, Gordon, Louisa G, Burmeister, Bryan, Hughes, Brett G M, McCarthy, Alexandra L, Perry, Chris, Chan, Raymond J, Paviour, Alana, Skerman, Helen, Batstone, Martin, Mackenzie, Lisa

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Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study von Fairfield, Cameron J, Pius, Riinu, Norman, Lisa, Harrison, Ewen M, Bogaert, Debby, de Silva, Thushan, Hiscox, Julian A, Ho, Antonia YW, Klenerman, Paul, Mentzer, Alexander J, Palmarini, Massimo, Pollakis, Georgios, Sancho-Shimizu, Vanessa, Pius, Riinu, Halpin, Sophie, Jackson, Clare, Scott-Brown, James, Wham, Murray, McDonald, Sara, Ashworth, Milton, Bakshi, Siddharth, Barlow, Samantha L, Catterall, Benjamin WA, Fisher, Lewis WS, Garcia-Dorival, Isabel, Holmes, Anthony, Jones, Christopher B, Koukorava, Chrysa, Lake, Annette, Lant, Suzannah, Lett, Lauren, Livoti, Lucia A, Mancini, Maria, Massey, Hannah, Maziere, Nicole, McEvoy, Laurence, Miah, Nahida S, Middleton, Joanna, Prince, Tessa, Ridley, P. Matthew, Shaw, Victoria E, Shears, Rebecca K, Szemiel, Agnieska, Taggart, Aislynn, Morrice, Kirstie, Murphy, Lee, Adeniji, Kayode, Agranoff, Daniel, Ashish, Abdul, Atkinson, Dougal, Barnass, Stella, Beadsworth, Michael, Clark, Tom, Collini, Paul, Dawson, Chris, Dervisevic, Samir, DuRand, Ingrid, Garg, Sanjeev, Gkrania-Klotsas, Effrossyni, Goldsmith, Arthur, Hardy, Elaine, Hartshorn, Stuart, Havalda, Peter, Hobrok, Maria, Jacobs, Michael, Jain, Susan, Jennings, Paul, Kerslake, Ian, Koch, Oliver, Limb, James, Linnett, Vanessa, Little, Jeff, McCullough, Katherine, Meda, Manjula, Minton, Jane, Moore, Elinoor, Morgan, Patrick, Mulla, Rohinton, Papineni, Padmasayee, Peters, Mark, Rae, Nikolas, Richardson, Neil, Ryan, Brendan, Shah, Aarti, Shankar-Hari, Manu, Sharma, Anil, Smith, Richard, Stambach, Tom, Subudhi, Pradeep, Thomas, Jo, Thompson, Chris, Tupper-Carey, Darell, Twagira, Mary, Vallotton, Nick, Vincent-Smith, Lisa, Visuvanathan, Shico, Wake, Rachel, Welters, Ingeborg, Whitehouse, Tony, Young, Peter

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Lung cancer: intragenic ERBB2 kinase mutations in tumours von Stephens, Philip, Hunter, Chris, Bignell, Graham, Edkins, Sarah, Davies, Helen, Teague, Jon, Stevens, Claire, O'Meara, Sarah, Smith, Raffaella, Parker, Adrian, Barthorpe, Andy, Blow, Matthew, Brackenbury, Lisa, Butler, Adam, Clarke, Oliver, Cole, Jennifer, Dicks, Ed, Dike, Angus, Drozd, Anja, Edwards, Ken, Forbes, Simon, Foster, Rebecca, Gray, Kristian, Greenman, Chris, Halliday, Kelly, Hills, Katy, Kosmidou, Vivienne, Lugg, Richard, Menzies, Andy, Perry, Janet, Petty, Robert, Raine, Keiran, Ratford, Lewis, Shepherd, Rebecca, Small, Alexandra, Stephens, Yvonne, Tofts, Calli, Varian, Jennifer, West, Sofie, Widaa, Sara, Yates, Andrew, Brasseur, Francis, Cooper, Colin S, Flanagan, Adrienne M, Knowles, Margaret, Leung, Suet Y, Louis, David N, Looijenga, Leendert H J, Malkowicz, Bruce, Pierotti, Marco A, Teh, Bin, Chenevix-Trench, Georgia, Weber, Barbara L, Yuen, Siu T, Harris, Grace, Goldstraw, Peter, Nicholson, Andrew G, Futreal, P Andrew, Wooster, Richard, Stratton, Michael R

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Somatic mutations of the protein kinase gene family in human lung cancer von DAVIES, Helen, HUNTER, Chris, PARKER, Adrian, O'MEARA, Sarah, AVIS, Tim, BARTHORPE, Syd, BRACKENBURY, Lisa, BUCK, Gemma, CLEMENTS, Jody, COLE, Jennifer, DICKS, Ed, EDWARDS, Ken, SMITH, Raffaella, FORBES, Simon, GORTON, Matthew, GRAY, Kristian, HALLIDAY, Kelly, HARRISON, Rachel, HILLS, Katy, HINTON, Jonathon, JONES, David, KOSMIDOU, Vivienne, LAMAN, Ross, STEPHENS, Philip, LUGG, Richard, MENZIES, Andrew, PERRY, Janet, PETTY, Robert, RAINE, Keiran, SHEPHERD, Rebecca, SMALL, Alexandra, SOLOMON, Helen, STEPHENS, Yvonne, TOFTS, Calli, GREENMAN, Chris, VARIAN, Jennifer, WEBB, Anthony, WEST, Sofie, WIDAA, Sara, YATES, Andrew, BRASSEUR, Francis, COOPER, Colin S, FLANAGAN, Adrienne M, GREEN, Anthony, KNOWLES, Maggie, BIGNELL, Graham, LEUNG, Suet Y, LOOIJENGA, Leendert H. J, MALKOWICZ, Bruce, PIEROTTI, Marco A, TEH, Bin T, YUEN, Siu T, LAKHANI, Sunil R, EASTON, Douglas F, WEBER, Barbara L, GOLDSTRAW, Peter, TEAGUE, Jon, BUTLER, Adam, EDKINS, Sarah, STEVENS, Claire

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Abstract 2713: Discovery and characterization of AZD8701, a high affinity antisense oligonucleotide targeting FOXP3 to relieve immunosuppression in cancer von Sinclair, Charles, Revenko, Alexey S., Johnson, R B., Peter, Alison, Taylor, Molly A., Hettrick, Lisa A., Klein, Stephanie, Solanki, Anisha, Chapman, Melissa, Yates, James, Angell, Helen K., Watt, Andrew, Gattis, Danielle, Monia, Brett P., Barry, Simon T., Lyne, Paul, Edbrooke, Mark, Goldberg, Frederick, Macleod, A R.

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An integrated approach to neuroscience care: An innovative model to support the new integrated care system von Balaratnam, Michelle S, Rugg-Gunn, Fergus J, Okin, Rachel, Powell, Freya, Prior, Stephen, Petrochilos, Panayiota, Shivji, Dhiren, Haider, Salman, Alim-Marvasti, Ali, Chandratheva, Arvind, Simister, Robert, Lane, Charlie, Macarimban, Roberto, Kaski, Diego, Athwal, Bal, Liu, Rebecca, Yates, Timothy, Rajakulendran, Sanjeev, Christofi, Gerry, Sandford, Jeremy, Ingram, Alexis, Bluston, Katherine, Weaver, Caroline, Odejide, Oluwaseun, Glod, George, Gungor, Gulsen, Nkrumah, Edmund, Markey, Donal, Hotton, Gary, Sidle, Katie, Kennedy, Jonathan, Penniall, Lisa, Plum, Helen, Antoniou, Anthony, Prema, Rakhee, Jeffries, Nadia, Walters, Carole, Stevenson, Valerie L, Drysdale, Malini, Tasnim, Sabiha, Hussain, Shahrima, Mackay, Lily, Baulk, Ryan, IIii, Bianca, Egan, David, Capp, Adrian, Turner, Patricia, Turner, Christopher

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A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer von Stephens, Philip, Edkins, Sarah, Davies, Helen, Greenman, Chris, Cox, Charles, Hunter, Chris, Bignell, Graham, Teague, Jon, Smith, Raffaella, Stevens, Claire, O'Meara, Sarah, Parker, Adrian, Tarpey, Patrick, Avis, Tim, Barthorpe, Andy, Brackenbury, Lisa, Buck, Gemma, Butler, Adam, Clements, Jody, Cole, Jennifer, Dicks, Ed, Edwards, Ken, Forbes, Simon, Gorton, Matthew, Gray, Kristian, Halliday, Kelly, Harrison, Rachel, Hills, Katy, Hinton, Jonathon, Jones, David, Kosmidou, Vivienne, Laman, Ross, Lugg, Richard, Menzies, Andrew, Perry, Janet, Petty, Robert, Raine, Keiran, Shepherd, Rebecca, Small, Alexandra, Solomon, Helen, Stephens, Yvonne, Tofts, Calli, Varian, Jennifer, Webb, Anthony, West, Sofie, Widaa, Sara, Yates, Andrew, Brasseur, Francis, Cooper, Colin S, Flanagan, Adrienne M, Green, Anthony, Knowles, Maggie, Leung, Suet Y, Looijenga, Leendert H J, Malkowicz, Bruce, Pierotti, Marco A, Teh, Bin, Yuen, Siu T, Nicholson, Andrew G, Lakhani, Sunil, Easton, Douglas F, Weber, Barbara L, Stratton, Michael R, Futreal, P Andrew, Wooster, Richard

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Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults von Bignell, Graham, Smith, Raffaella, Hunter, Chris, Stephens, Philip, Davies, Helen, Greenman, Chris, Teague, Jon, Butler, Adam, Edkins, Sarah, Stevens, Claire, O'Meara, Sarah, Parker, Adrian, Avis, Tim, Barthorpe, Syd, Brackenbury, Lisa, Buck, Gemma, Clements, Jody, Cole, Jennifer, Dicks, Ed, Edwards, Ken, Forbes, Simon, Gorton, Matthew, Gray, Kristian, Halliday, Kelly, Harrison, Rachel, Hills, Katy, Hinton, Jonathon, Jones, David, Kosmidou, Vivienne, Laman, Ross, Lugg, Richard, Menzies, Andrew, Perry, Janet, Petty, Robert, Raine, Keiran, Shepherd, Rebecca, Small, Alexandra, Solomon, Helen, Stephens, Yvonne, Tofts, Calli, Varian, Jennifer, Webb, Anthony, West, Sofie, Widaa, Sara, Yates, Andy, Gillis, Ad J. M., Stoop, Hans J., van Gurp, Ruud J. H. L. M., Oosterhuis, J. Wolter, Looijenga, Leendert H. J., Futreal, P. Andrew, Wooster, Richard, Stratton, Michael R.

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Baseline morbidity in 2,990 adult African volunteers recruited to characterize laboratory reference intervals for future HIV vaccine clinical trials von Stevens, Wendy, Kamali, Anatoli, Karita, Etienne, Anzala, Omu, Sanders, Eduard J, Jaoko, Walter, Kaleebu, Pontiano, Mulenga, Joseph, Dally, Len, Fast, Pat, Gilmour, Jill, Farah, Bashir, Birungi, Josephine, Hughes, Peter, Manigart, Olivier, Stevens, Gwynn, Yates, Sarah, Thomson, Helen, von Lieven, Andrea, Krebs, Marietta, Price, Matt A, Stoll-Johnson, Lisa, Ketter, Nzeera

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