Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones von Tsukada, Kento, Shinki, Shono, Kaneko, Akiho, Murakami, Kazuma, Irie, Kazuhiro, Murai, Masatoshi, Miyoshi, Hideto, Dan, Shingo, Kawaji, Kumi, Hayashi, Hironori, Kodama, Eiichi N., Hori, Aki, Salim, Emil, Kuraishi, Takayuki, Hirata, Naoya, Kanda, Yasunari, Asai, Teigo

Volltext

Cryoprotectant-free cryopreservation of mammalian cells by superflash freezing von Shinose, Masato, Watanabe, Hiroki, Yamada, Shigeru, Kanda, Yasunari

Volltext

Evaluation of Barrier Functions in Human iPSC-Derived Intestinal Epithelium von Yamada, Shigeru, Kanda, Yasunari

Volltext

Development of torsadogenic risk assessment using human induced pluripotent stem cell-derived cardiomyocytes: Japan iPS Cardiac Safety Assessment (JiCSA) update von Kanda, Yasunari, Yamazaki, Daiju, Osada, Tomoharu, Yoshinaga, Takashi, Sawada, Kohei

Volltext

Comprehensive Cardiotoxicity Assessment of COVID-19 Treatments Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes von Yanagida, Shota, Satsuka, Ayano, Hayashi, Sayo, Ono, Atsushi, Kanda, Yasunari

Volltext

International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment von Blinova, Ksenia, Dang, Qianyu, Millard, Daniel, Smith, Godfrey, Pierson, Jennifer, Guo, Liang, Brock, Mathew, Lu, Hua Rong, Kraushaar, Udo, Zeng, Haoyu, Shi, Hong, Zhang, Xiaoyu, Sawada, Kohei, Osada, Tomoharu, Kanda, Yasunari, Sekino, Yuko, Pang, Li, Feaster, Tromondae K., Kettenhofen, Ralf, Stockbridge, Norman, Strauss, David G., Gintant, Gary

Volltext

5-Fluorouracil inhibits neural differentiation via Mfn1/2 reduction in human induced pluripotent stem cells von Yamada, Shigeru, Yamazaki, Daiju, Kanda, Yasunari

Volltext

Transforming Growth Factor Beta Promotes the Expansion of Cancer Stem Cells via S1PR3 by Ligand-Independent Notch Activation von Hirata, Naoya, Yamada, Shigeru, Yanagida, Shota, Ono, Atsushi, Yasuhiko, Yukuto, Kanda, Yasunari

Volltext

Depolysulfidation of Drp1 induced by low-dose methylmercury exposure increases cardiac vulnerability to hemodynamic overload von Nishimura, Akiyuki, Shimoda, Kakeru, Tanaka, Tomohiro, Toyama, Takashi, Nishiyama, Kazuhiro, Shinkai, Yasuhiro, Numaga-Tomita, Takuro, Yamazaki, Daiju, Kanda, Yasunari, Akaike, Takaaki, Kumagai, Yoshito, Nishida, Motohiro

Volltext

Chlorpyrifos inhibits neural induction via Mfn1-mediated mitochondrial dysfunction in human induced pluripotent stem cells von Yamada, Shigeru, Kubo, Yusuke, Yamazaki, Daiju, Sekino, Yuko, Kanda, Yasunari

Volltext

Tobacco nitrosamine NNK increases ALDH-positive cells via ROS-Wnt signaling pathway in A549 human lung cancer cells von Hirata, Naoya, Yamada, Shigeru, Sekino, Yuko, Kanda, Yasunari

Volltext

Chronic cardiotoxicity assessment of BMS-986094, a guanosine nucleotide analogue, using human iPS cell-derived cardiomyocytes von Yanagida, Shota, Satsuka, Ayano, Hayashi, Sayo, Ono, Atsushi, Kanda, Yasunari

Volltext

Neuronal differentiation reporter mice as a new methodology for detecting in vivo developmental neurotoxicity von Ishida, Keishi, Tatsumi, Kanoko, Minamigawa, Yoshiki, Mori, Kazuma, Matsumaru, Daisuke, Nagase, Hisamitsu, Kanda, Yasunari, Takuma, Kazuhiro, Nakanishi, Tsuyoshi

Volltext

Electrophysiological Characteristics of Human iPSC-Derived Cardiomyocytes for the Assessment of Drug-Induced Proarrhythmic Potential von Yamamoto, Wataru, Asakura, Keiichi, Ando, Hiroyuki, Taniguchi, Tomohiko, Ojima, Atsuko, Uda, Takaaki, Osada, Tomoharu, Hayashi, Seiji, Kasai, Chieko, Miyamoto, Norimasa, Tashibu, Hiroyuki, Yoshinaga, Takashi, Yamazaki, Daiju, Sugiyama, Atsushi, Kanda, Yasunari, Sawada, Kohei, Sekino, Yuko

Volltext

Lithocholic Acid Derivatives as Potent Vitamin D Receptor Agonists von Sasaki, Harue, Masuno, Hiroyuki, Kawasaki, Haru, Yoshihara, Ayana, Numoto, Nobutaka, Ito, Nobutoshi, Ishida, Hiroaki, Yamamoto, Keiko, Hirata, Naoya, Kanda, Yasunari, Kawachi, Emiko, Kagechika, Hiroyuki, Tanatani, Aya

Volltext

Highly sensitive in vitro methods for detection of residual undifferentiated cells in retinal pigment epithelial cells derived from human iPS cells von Kuroda, Takuya, Yasuda, Satoshi, Kusakawa, Shinji, Hirata, Naoya, Kanda, Yasunari, Suzuki, Kazuhiro, Takahashi, Masayo, Nishikawa, Shin-Ichi, Kawamata, Shin, Sato, Yoji

Volltext

Specific induction and long-term maintenance of high purity ventricular cardiomyocytes from human induced pluripotent stem cells von Fukushima, Hiroyuki, Yoshioka, Miki, Kawatou, Masahide, Lopez-Davila, Victor, Takeda, Masafumi, Kanda, Yasunari, Sekino, Yuko, Yoshida, Yoshinori, Yamashita, Jun K.

Volltext

SARS-CoV-2 causes dysfunction in human iPSC-derived brain microvascular endothelial cells potentially by modulating the Wnt signaling pathway von Yamada, Shigeru, Hashita, Tadahiro, Yanagida, Shota, Sato, Hiroyuki, Yasuhiko, Yukuto, Okabe, Kaori, Noda, Takamasa, Nishida, Motohiro, Matsunaga, Tamihide, Kanda, Yasunari

Volltext

Proarrhythmia risk prediction using human induced pluripotent stem cell-derived cardiomyocytes von Yamazaki, Daiju, Kitaguchi, Takashi, Ishimura, Masakazu, Taniguchi, Tomohiko, Yamanishi, Atsuhiro, Saji, Daisuke, Takahashi, Etsushi, Oguchi, Masao, Moriyama, Yuta, Maeda, Sanae, Miyamoto, Kaori, Morimura, Kaoru, Ohnaka, Hiroki, Tashibu, Hiroyuki, Sekino, Yuko, Miyamoto, Norimasa, Kanda, Yasunari

Volltext

Pharmacological β-adrenoceptor blockade can augment torsadogenic action of IKr inhibitor: Comparison of proarrhythmic effects of d-sotalol and dl-sotalol in the chronic atrioventri... von Goto, Ai, Hagiwara-Nagasawa, Mihoko, Chiba, Koki, Kambayashi, Ryuichi, Nunoi, Yoshio, Izumi-Nakaseko, Hiroko, Matsumoto, Akio, Kanda, Yasunari, Sugiyama, Atsushi

Volltext