Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine von Barekatain, Yasaman, Ackroyd, Jeffrey J., Yan, Victoria C., Khadka, Sunada, Wang, Lin, Chen, Ko-Chien, Poral, Anton H., Tran, Theresa, Georgiou, Dimitra K., Arthur, Kenisha, Lin, Yu-Hsi, Satani, Nikunj, Ballato, Elliot S., Behr, Eliot I., deCarvalho, Ana C., Verhaak, Roel G. W., de Groot, John, Huse, Jason T., Asara, John M., Kalluri, Raghu, Muller, Florian L.

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Structure-guided microbial targeting of antistaphylococcal prodrugs von Miller, Justin J, Shah, Ishaan T, Hatten, Jayda, Barekatain, Yasaman, Mueller, Elizabeth A, Moustafa, Ahmed M, Edwards, Rachel L, Dowd, Cynthia S, Hoops, Geoffrey C, Johnson, R Jeremy, Planet, Paul J, Muller, Florian L, Jez, Joseph M, Odom John, Audrey R

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Correction: Structure-guided microbial targeting of antistaphylococcal prodrugs von Miller, Justin J, Shah, Ishaan T, Hatten, Jayda, Barekatain, Yasaman, Mueller, Elizabeth A, Moustafa, Ahmed M, Edwards, Rachel L, Dowd, Cynthia S, Hoops, Geoffrey C, Johnson, R Jeremy, Planet, Paul, Muller, Florian L, Jez, Joseph, Odom John, Audrey R

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An enolase inhibitor for the targeted treatment of ENO1-deleted cancers von Lin, Yu-Hsi, Satani, Nikunj, Hammoudi, Naima, Yan, Victoria C., Barekatain, Yasaman, Khadka, Sunada, Ackroyd, Jeffrey J., Georgiou, Dimitra K., Pham, Cong-Dat, Arthur, Kenisha, Maxwell, David, Peng, Zhenghong, Leonard, Paul G., Czako, Barbara, Pisaneschi, Federica, Mandal, Pijus, Sun, Yuting, Zielinski, Rafal, Pando, Susana Castro, Wang, Xiaobo, Tran, Theresa, Xu, Quanyu, Wu, Qi, Jiang, Yongying, Kang, Zhijun, Asara, John M., Priebe, Waldemar, Bornmann, William, Marszalek, Joseph R., DePinho, Ronald A., Muller, Florian L.

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Targeting Host Glycolysis as a Strategy for Antimalarial Development von Jezewski, Andrew J, Lin, Yu-Hsi, Reisz, Julie A, Culp-Hill, Rachel, Barekatain, Yasaman, Yan, Victoria C, D'Alessandro, Angelo, Muller, Florian L, Odom John, Audrey R

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Impaired anaplerosis is a major contributor to glycolysis inhibitor toxicity in glioma von Khadka, Sunada, Arthur, Kenisha, Barekatain, Yasaman, Behr, Eliot, Washington, Mykia, Ackroyd, Jeffrey, Crowley, Kaitlyn, Suriyamongkol, Pornpa, Lin, Yu-Hsi, Pham, Cong-Dat, Zielinski, Rafal, Trujillo, Marissa, Galligan, James, Georgiou, Dimitra K, Asara, John, Muller, Florian

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Robust detection of oncometabolic aberrations by 1H–13C heteronuclear single quantum correlation in intact biological specimens von Barekatain, Yasaman, Yan, Victoria C., Arthur, Kenisha, Ackroyd, Jeffrey J., Khadka, Sunada, De Groot, John, Huse, Jason T., Muller, Florian L.

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KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells von Mahadevan, Krishnan K., McAndrews, Kathleen M., LeBleu, Valerie S., Yang, Sujuan, Lyu, Hengyu, Li, Bingrui, Sockwell, Amari M., Kirtley, Michelle L., Morse, Sami J., Moreno Diaz, Barbara A., Kim, Michael P., Feng, Ningping, Lopez, Anastasia M., Guerrero, Paola A., Paradiso, Francesca, Sugimoto, Hikaru, Arian, Kent A., Ying, Haoqiang, Barekatain, Yasaman, Sthanam, Lakshmi Kavitha, Kelly, Patience J., Maitra, Anirban, Heffernan, Timothy P., Kalluri, Raghu

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Quantification of Phosphonate Drugs by 1 H– 31 P HSQC Shows That Rats Are Better Models of Primate Drug Exposure than Mice von Barekatain, Yasaman, Khadka, Sunada, Harris, Kristen, Delacerda, Jorge, Yan, Victoria C., Chen, Ko-Chien, Pham, Cong-Dat, Uddin, Md. Nasir, Avritcher, Rony, Eisenberg, Eugene J., Kalluri, Raghu, Millward, Steven W., Muller, Florian L.

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KRASG12D inhibition reprograms the tumor microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells von Mahadevan, Krishnan K., McAndrews, Kathleen M., LeBleu, Valerie S., Yang, Sujuan, Lyu, Hengyu, Li, Bingrui, Sockwell, Amari M., Kirtley, Michelle L., Morse, Sami J., Diaz, Barbara A. Moreno, Kim, Michael P., Feng, Ningping, Lopez, Anastasia M., Guerrero, Paola A., Paradiso, Francesca, Sugimoto, Hikaru, Arian, Kent A., Ying, Haoqiang, Barekatain, Yasaman, Sthanam, Lakshmi Kavitha, Kelly, Patience J., Maitra, Anirban, Heffernan, Timothy P., Kalluri, Raghu

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Quantification of Phosphonate Drugs by 1H–31P HSQC Shows That Rats Are Better Models of Primate Drug Exposure than Mice von Barekatain, Yasaman, Khadka, Sunada, Harris, Kristen, Delacerda, Jorge, Yan, Victoria C., Chen, Ko-Chien, Pham, Cong-Dat, Uddin, Md. Nasir, Avritcher, Rony, Eisenberg, Eugene J., Kalluri, Raghu, Millward, Steven W., Muller, Florian L.

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Prodrugs of a 1‑Hydroxy-2-oxopiperidin-3-yl Phosphonate Enolase Inhibitor for the Treatment of ENO1-Deleted Cancers von Yan, Victoria C., Pham, Cong-Dat, Ballato, Elliot S., Yang, Kristine L., Arthur, Kenisha, Khadka, Sunada, Barekatain, Yasaman, Shrestha, Prakriti, Tran, Theresa, Poral, Anton H., Washington, Mykia, Raghavan, Sudhir, Czako, Barbara, Pisaneschi, Federica, Lin, Yu-Hsi, Satani, Nikunj, Hammoudi, Naima, Ackroyd, Jeffrey J., Georgiou, Dimitra K., Millward, Steven W., Muller, Florian L.

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Abstract 1073: PRMT5 inhibition synergizes with a natural small molecule compound to kill MTAP- deleted cells and suppress tumor growth von Barekatain, Yasaman, LaBella, Kyle, Sugimoto, Hikaru, Harris, Kristen, Khadka, Sunada, Muller, Florian, Kalluri, Raghu

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TAMI-62. ANGIOGENESIS INHIBITORS STRONGLY SYNERGIZE WITH THERAPEUTICS TARGETING TUMOR METABOLISM von Khadka, Sunada, Lin, Yu-Hsi, Ackroyd, Jeffrey, Arthur, Kenisha, Barekatain, Yasaman, Poral, Anton, Tran, Theresa, Georgiou, Dimitra, de Groot, John, Huse, Jason, Asara, John, Muller, Florian

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Abstract 2395: Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine von Barekatain, Yasaman, Ackroyd, Jeffrey, Yan, Victoria, Khadka, Sunada, Chen, Ko-Chien, Kalluri, Raghu, de Groot, John, Huse, Jason, muller, Florian

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Abstract 3208: Angiogenesis inhibitors strongly synergize with therapeutics targeting tumor metabolism von Khadka, Sunada, Lin, Yu-Hsi, Ackroyd, Jeffery, Arthur, Kenisha, Barekatain, Yasaman, Poral, Anton, Tran, Theresa, Behr, Eliot, Chen, Yining, Georgiou, Dimitra, Depinho, Ronald, Muller, Florian

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KRAS G12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8 + T cells von Mahadevan, Krishnan K, McAndrews, Kathleen M, LeBleu, Valerie S, Yang, Sujuan, Lyu, Hengyu, Li, Bingrui, Sockwell, Amari M, Kirtley, Michelle L, Morse, Sami J, Moreno Diaz, Barbara A, Kim, Michael P, Feng, Ningping, Lopez, Anastasia M, Guerrero, Paola A, Paradiso, Francesca, Sugimoto, Hikaru, Arian, Kent A, Ying, Haoqiang, Barekatain, Yasaman, Sthanam, Lakshmi Kavitha, Kelly, Patience J, Maitra, Anirban, Heffernan, Timothy P, Kalluri, Raghu

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Comparative Pharmacology of a Bis-Pivaloyloxymethyl Phosphonate Prodrug Inhibitor of Enolase after Oral and Parenteral Administration von Yan, Victoria C., Barekatain, Yasaman, Lin, Yu-Hsi, Satani, Nikunj, Hammoudi, Naima, Arthur, Kenisha, Georgiou, Dimitra K., Jiang, Yongying, Sun, Yuting, Marszalek, Joseph R., Millward, Steven W., Muller, Florian L.

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Robust detection of oncometabolic aberrations by 1 H- 13 C heteronuclear single quantum correlation in intact biological specimens von Barekatain, Yasaman, Yan, Victoria C, Arthur, Kenisha, Ackroyd, Jeffrey J, Khadka, Sunada, De Groot, John, Huse, Jason T, Muller, Florian L

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Antimicrobial Prodrug Activation by the Staphylococcal Glyoxalase GloB von Mikati, Marwa O, Miller, Justin J, Osbourn, Damon M, Barekatain, Yasaman, Ghebremichael, Naomi, Shah, Ishaan T, Burnham, Carey-Ann D, Heidel, Kenneth M, Yan, Victoria C, Muller, Florian L, Dowd, Cynthia S, Edwards, Rachel L, Odom John, Audrey R

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