6065 POSTER Significance of Mutation in K-Ras Gene in Pathogenesis and Clinical Course of Colorectal Cancer von Belyaeva, A.V, Yanus, G.A, Imyanitov, E.N, Suspitsin, E.N, Goulyaev, A.V, levleva, A.G, Moiseenko, A.B

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1142P Improved duplex sequencing-based method suitable for detection of hypermutator phenotype in FFPE-derived tumor samples von Mitiushkina, N.V., Yanus, G.A., Laidus, T.A., Bizin, I.V., Ivantsov, A.O., Imyanitov, E.N.

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21P Analysis of germline variants in the immune response-related genes in BRCA1 mutation carriers: Possible modifying effect on age-dependent BRCA1 penetrance von Kuligina, E.S., Romanko, A.A., Suspitsin, E.N., Tumakova, A.V., Martianov, A.S., Bizin, I.V., Gorgul, J., Yanus, G.A., Kashyap, A., Cybulski, C., Jakubowska, A., Lubiński, J., Imyanitov, E.N.

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1785P Tumor irradiation may improve the sensitivity of liquid biopsy: The analysis of RAS/RAF mutations in plasma obtained from radiotherapy-treated rectal cancer patients von Imyanitov, E.N., Laidus, T.A., Moiseyenko, F., Belukhin, S., Stepanova, E., Zakharova, M., Chernobrivtseva, V., Aliev, I., Sharabura, T., Moiseyenko, V.M., Aleksakhina, S., Martianov, A., Yanus, G.A., Togo, A., Kuligina, E.S.

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Sequencing of KRAS and NRAS in 1501 colorectal carcinomas reveals significant share of mutations, which are not included in common diagnostic kits von Imyanitov, E.N., Mitiushkina, N.V., Kuligina, E.S., Holmatov, M., Yanus, G.A., Demidova, I., Kekeeva, T., Gordiev, M., Kharitonova, E., Tsimafeyeu, I., Tjulandin, S.

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Spectrum of APC and MUTYH germ‐line mutations in Russian patients with colorectal malignancies von Yanus, G.A., Akhapkina, T.A., Ivantsov, A.O., Preobrazhenskaya, E.V., Aleksakhina, S.N., Bizin, I.V., Sokolenko, A.P., Mitiushkina, N.V., Kuligina, E.Sh, Suspitsin, E.N., Venina, A.R., Holmatov, M.M., Zaitseva, O.A., Yatsuk, O.S., Pashkov, D.V., Belyaev, A.M., Togo, A.V., Imyanitov, E.N., Iyevleva, A.G.

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MOLECULAR MARKERS OF SENSITIVITY AND RESISTANCE OF COLORECTAL CANCER TO ANTI-EGFR THERAPY von Ivantsov, A.O., Yanus, G.A., Suspitsin, E.N., Anisimova, E.I., Imyanitov, E.N.

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Hereditary breast-ovarian cancer syndrome in Russia von Sokolenko, A P, Iyevleva, A G, Mitiushkina, N V, Suspitsin, E N, Preobrazhenskaya, E V, Kuligina, E Sh, Voskresenskiy, D A, Lobeiko, O S, Krylova, N Yu, Gorodnova, T V, Buslov, K G, Bit-Sava, E M, Dolmatov, G D, Porhanova, N V, Polyakov, I S, Abysheva, S N, Katanugina, A S, Baholdin, D V, Yanus, G A, Togo, A V, Moiseyenko, V M, Maximov, S Ya, Semiglazov, V F, Imyanitov, E N

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Supplementary Material for: Lack of Response to Imatinib in Melanoma Carrying Rare KIT Mutation р.T632I von Orlova, K.V., Yanus, G.A., Aleksakhina, S.N., Venina, A.R., Iyevleva, A.G., Demidov, L.V., Imyanitov, E.N.

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