Concepts of Artificial Intelligence for Computer-Assisted Drug Discovery von Yang, Xin, Wang, Yifei, Byrne, Ryan, Schneider, Gisbert, Yang, Shengyong

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Small molecules in targeted cancer therapy: advances, challenges, and future perspectives von Zhong, Lei, Li, Yueshan, Xiong, Liang, Wang, Wenjing, Wu, Ming, Yuan, Ting, Yang, Wei, Tian, Chenyu, Miao, Zhuang, Wang, Tianqi, Yang, Shengyong

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Information Disclosure of Network Platform and Corporate Social Responsibility Based on Cloud Computing von Shengyong, Yang

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Structures of signaling complexes of lipid receptors S1PR1 and S1PR5 reveal mechanisms of activation and drug recognition von Yuan, Yuan, Jia, Guowen, Wu, Chao, Wang, Wei, Cheng, Lin, Li, Qian, Li, Ziyan, Luo, Kaidong, Yang, Shengyong, Yan, Wei, Su, Zhaoming, Shao, Zhenhua

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Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials von Cheng, Yuan, He, Cai, Wang, Manni, Ma, Xuelei, Mo, Fei, Yang, Shengyong, Han, Junhong, Wei, Xiawei

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Cationic nanocarriers induce cell necrosis through impairment of Na^＋/K^＋-ATPase and cause subsequent inflammatory response von Wei, Xiawei, Shao, Bin, He, Zhiyao, Ye, Tinghong, Luo, Min, Sang, Yaxiong, Liang, Xiao, Wang, Wei, Luo, Shuntao, Yang, Shengyong, Zhang, Shuang, Gong, Changyang, Gou, Maling, Deng, Hongxing, Zhao, Yinglan, Yang, Hanshuo, Deng, Senyi, Zhao, Chengjian, Yang, Li, Qian, Zhiyong, Li, Jiong, Sun, Xun, Han, Jiahuai, Jiang, Chengyu, Wu, Min, Zhang, Zhirong

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Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode von Yan, Wei, Cheng, Lin, Wang, Wei, Wu, Chao, Yang, Xin, Du, Xiaozhe, Ma, Liang, Qi, Shiqian, Wei, Yuquan, Lu, Zhiliang, Yang, Shengyong, Shao, Zhenhua

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Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor von Li, Yueshan, Zhang, Liting, Wang, Yifei, Zou, Jun, Yang, Ruicheng, Luo, Xinling, Wu, Chengyong, Yang, Wei, Tian, Chenyu, Xu, Haixing, Wang, Falu, Yang, Xin, Li, Linli, Yang, Shengyong

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Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes von Xiao, Peng, Yan, Wei, Gou, Lu, Zhong, Ya-Ni, Kong, Liangliang, Wu, Chao, Wen, Xin, Yuan, Yuan, Cao, Sheng, Qu, Changxiu, Yang, Xin, Yang, Chuan-Cheng, Xia, Anjie, Hu, Zhenquan, Zhang, Qianqian, He, Yong-Hao, Zhang, Dao-Lai, Zhang, Chao, Hou, Gui-Hua, Liu, Huanxiang, Zhu, Lizhe, Fu, Ping, Yang, Shengyong, Rosenbaum, Daniel M., Sun, Jin-Peng, Du, Yang, Zhang, Lei, Yu, Xiao, Shao, Zhenhua

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The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression von Xiong, Yu, Li, Linli, Zhang, Liting, Cui, Yangyang, Wu, Chengyong, Li, Hui, Chen, Kai, Yang, Qiuyuan, Xiang, Rong, Hu, Yiguo, Huang, Shile, Wei, Yuquan, Yang, Shengyong

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Non-classical ferroptosis inhibition by a small molecule targeting PHB2 von Yang, Wei, Mu, Bo, You, Jing, Tian, Chenyu, Bin, Huachao, Xu, Zhiqiang, Zhang, Liting, Ma, Ronggang, Wu, Ming, Zhang, Guo, Huang, Chong, Li, Linli, Shao, Zhenhua, Dai, Lunzhi, Désaubry, Laurent, Yang, Shengyong

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Structural insights into sphingosine-1-phosphate recognition and ligand selectivity of S1PR3–Gi signaling complexes von Zhao, Chang, Cheng, Lin, Wang, Wei, Wang, Heli, Luo, Yongbo, Feng, Yuying, Wang, Xuehui, Fu, Hong, Cai, Ye, Yang, Shengyong, Fu, Ping, Yan, Wei, Shao, Zhenhua

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Crystal structure of SARS-CoV-2 nsp10/nsp16 2′-O-methylase and its implication on antiviral drug design von Lin, Sheng, Chen, Hua, Ye, Fei, Chen, Zimin, Yang, Fanli, Zheng, Yue, Cao, Yu, Qiao, Jingxin, Yang, Shengyong, Lu, Guangwen

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Multispecific drugs: the fourth wave of biopharmaceutical innovation von Wang, Yifei, Yang, Shengyong

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Discovery of benzo[d]oxazol-2(3H)-one derivatives as a new class of TNIK inhibitors for the treatment of colorectal cancer von Luo, Xinling, Yang, Ruicheng, Li, Yueshan, Zhang, Liting, Yang, Shengyong, Li, Linli

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HDAC inhibitors improve CRISPR-Cas9 mediated prime editing and base editing von Liu, Nan, Zhou, Lifang, Lin, Guifeng, Hu, Yun, Jiao, Yaoge, Wang, Yanhong, Liu, Jingming, Yang, Shengyong, Yao, Shaohua

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Jumonji domain‐containing protein 6 protein and its role in cancer von Yang, Jing, Chen, Siyuan, Yang, Yanfei, Ma, Xuelei, Shao, Bin, Yang, Shengyong, Wei, Yuquan, Wei, Xiawei

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Targeting Pin1 by inhibitor API‐1 regulates microRNA biogenesis and suppresses hepatocellular carcinoma development von Pu, Wenchen, Li, Jiao, Zheng, Yuanyuan, Shen, Xianyan, Fan, Xin, Zhou, Jian‐Kang, He, Juan, Deng, Yulan, Liu, Xuesha, Wang, Chun, Yang, Shengyong, Chen, Qiang, Liu, Lunxu, Zhang, Guolin, Wei, Yu‐Quan, Peng, Yong

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Liposomal honokiol induced lysosomal degradation of Hsp90 client proteins and protective autophagy in both gefitinib-sensitive and gefitinib-resistant NSCLC cells von Yang, Jianhong, Wu, Wenshuang, Wen, Jiaolin, Ye, Haoyu, Luo, Hong, Bai, Peng, Tang, Minghai, Wang, Fang, Zheng, Li, Yang, Shengyong, Li, Weimin, Peng, Aihua, Yang, Li, Wan, Li, Chen, Lijuan

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Discovery of a new class of JMJD6 inhibitors and structure–activity relationship study von Wang, Tianqi, Zhang, Rong, Liu, Yang, Fang, Zhen, Zhang, Hailin, Fan, Yan, Yang, Shengyong, Xiang, Rong

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