lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs von Yang, Liuqing, Lin, Chunru, Jin, Chunyu, Yang, Joy C., Tanasa, Bogdan, Li, Wenbo, Merkurjev, Daria, Ohgi, Kenneth A., Meng, Da, Zhang, Jie, Evans, Christopher P., Rosenfeld, Michael G.

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Intracrine Androgens and AKR1C3 Activation Confer Resistance to Enzalutamide in Prostate Cancer von Liu, Chengfei, Lou, Wei, Zhu, Yezi, Yang, Joy C, Nadiminty, Nagalakshmi, Gaikwad, Nilesh W, Evans, Christopher P, Gao, Allen C

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Cross-Resistance Among Next-Generation Antiandrogen Drugs Through the AKR1C3/AR-V7 Axis in Advanced Prostate Cancer von Zhao, Jinge, Ning, Shu, Lou, Wei, Yang, Joy C, Armstrong, Cameron M, Lombard, Alan P, D'Abronzo, Leandro S, Evans, Christopher P, Gao, Allen C, Liu, Chengfei

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Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer von Liu, Chengfei, Lou, Wei, Yang, Joy C., Liu, Liangren, Armstrong, Cameron M., Lombard, Alan P., Zhao, Ruining, Noel, Onika D. V., Tepper, Clifford G., Chen, Hong-Wu, Dall’Era, Marc, Evans, Christopher P., Gao, Allen C.

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AKR1C3 Promotes AR-V7 Protein Stabilization and Confers Resistance to AR-Targeted Therapies in Advanced Prostate Cancer von Liu, Chengfei, Yang, Joy C, Armstrong, Cameron M, Lou, Wei, Liu, Liangren, Qiu, Xiaomin, Zou, Binhao, Lombard, Alan P, D'Abronzo, Leandro S, Evans, Christopher P, Gao, Allen C

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KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC von Wang, Hung-Jung, Pochampalli, Mamata, Wang, Ling-Yu, Zou, June X, Li, Pei-Shan, Hsu, Sheng-Chieh, Wang, Bi-Juan, Huang, Shih-Han, Yang, Ping, Yang, Joy C., Chu, Cheng-Ying, Hsieh, Chia-Ling, Sung, Shian-Ying, Li, Chien-Feng, Tepper, Clifford G., Ann, David K., Gao, Allen C., Evans, Christopher P., Izumiya, Yoshihiro, Chuu, Chi-Pin, Wang, Wen-Ching, Chen, Hong-Wu, Kung, Hsing-Jien

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KDM4A Coactivates E2F1 to Regulate the PDK-Dependent Metabolic Switch between Mitochondrial Oxidation and Glycolysis von Wang, Ling-Yu, Hung, Chiu-Lien, Chen, Yun-Ru, Yang, Joy C., Wang, Junjian, Campbell, Mel, Izumiya, Yoshihiro, Chen, Hong-Wu, Wang, Wen-Ching, Ann, David K., Kung, Hsing-Jien

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Allosteric inhibition of HSP70 in collaboration with STUB1 augments enzalutamide efficacy in antiandrogen resistant prostate tumor and patient-derived models von Xu, Pengfei, Yang, Joy C., Ning, Shu, Chen, Bo, Nip, Christopher, Wei, Qiang, Liu, Liangren, Johnson, Oleta T., Gao, Allen C., Gestwicki, Jason E., Evans, Christopher P., Liu, Chengfei

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Intra versus Inter Cross-resistance Determines Treatment Sequence between Taxane and AR-Targeting Therapies in Advanced Prostate Cancer von Lombard, Alan P, Liu, Liangren, Cucchiara, Vito, Liu, Chengfei, Armstrong, Cameron M, Zhao, Ruining, Yang, Joy C, Lou, Wei, Evans, Christopher P, Gao, Allen C

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Bioengineered BERA-Wnt5a siRNA Targeting Wnt5a/FZD2 Signaling Suppresses Advanced Prostate Cancer Tumor Growth and Enhances Enzalutamide Treatment von Ning, Shu, Liu, Chengfei, Lou, Wei, Yang, Joy C, Lombard, Alan P, D'Abronzo, Leandro S, Batra, Neelu, Yu, Ai-Ming, Leslie, Amy R, Sharifi, Masuda, Evans, Christopher P, Gao, Allen C

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Niclosamide and Bicalutamide Combination Treatment Overcomes Enzalutamide- and Bicalutamide-Resistant Prostate Cancer von Liu, Chengfei, Armstrong, Cameron M, Lou, Wei, Lombard, Alan P, Cucchiara, Vito, Gu, Xinwei, Yang, Joy C, Nadiminty, Nagalakshmi, Pan, Chong-Xian, Evans, Christopher P, Gao, Allen C

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Targeting molecular resistance in castration-resistant prostate cancer von Chandrasekar, Thenappan, Yang, Joy C, Gao, Allen C, Evans, Christopher P

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Proteostasis perturbation of N-Myc leveraging HSP70 mediated protein turnover improves treatment of neuroendocrine prostate cancer von Xu, Pengfei, Yang, Joy C., Chen, Bo, Ning, Shu, Zhang, Xiong, Wang, Leyi, Nip, Christopher, Shen, Yuqiu, Johnson, Oleta T., Grigorean, Gabriela, Phinney, Brett, Liu, Liangren, Wei, Qiang, Corey, Eva, Tepper, Clifford G., Chen, Hong-Wu, Evans, Christopher P., Dall’Era, Marc A., Gao, Allen C., Gestwicki, Jason E., Liu, Chengfei

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Chem-seq permits identification of genomic targets of drugs against androgen receptor regulation selected by functional phenotypic screens von Jin, Chunyu, Yang, Liuqing, Xie, Min, Lin, Chunru, Merkurjev, Daria, Yang, Joy C., Tanasa, Bogdan, Oh, Soohwan, Zhang, Jie, Ohgi, Kenneth A., Zhou, Hongyan, Li, Wenbo, Evans, Christopher P., Ding, Sheng, Rosenfeld, Michael G.

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miR-124 and Androgen Receptor Signaling Inhibitors Repress Prostate Cancer Growth by Downregulating Androgen Receptor Splice Variants, EZH2, and Src von Shi, Xu-Bao, Ma, Ai-Hong, Xue, Lingru, Li, Meimei, Nguyen, Hao G, Yang, Joy C, Tepper, Clifford G, Gandour-Edwards, Regina, Evans, Christopher P, Kung, Hsing-Jien, deVere White, Ralph W

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Androgen receptor blockade resistance with enzalutamide in prostate cancer results in immunosuppressive alterations in the tumor immune microenvironment von Xu, Pengfei, Yang, Joy C, Chen, Bo, Nip, Christopher, Van Dyke, Jonathan E, Zhang, Xiong, Chen, Hong-Wu, Evans, Christopher P, Murphy, William J, Liu, Chengfei

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The Immunotherapy and Immunosuppressive Signaling in Therapy-Resistant Prostate Cancer von Xu, Pengfei, Wasielewski, Logan J., Yang, Joy C., Cai, Demin, Evans, Christopher P., Murphy, William J., Liu, Chengfei

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Interleukin-6 Regulates Androgen Synthesis in Prostate Cancer Cells von Chun, Jae Yeon, Nadiminty, Nagalakshmi, Dutt, Smitha, Lou, Wei, Yang, Joy C, Kung, Hsing-Jien, Evans, Christopher P, Gao, Allen C

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Mechanisms of resistance in castration-resistant prostate cancer (CRPC) von Chandrasekar, Thenappan, Yang, Joy C, Gao, Allen C, Evans, Christopher P

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Simultaneous targeting of Src kinase and receptor tyrosine kinase results in synergistic inhibition of renal cell carcinoma proliferation and migration von Bai, Lanfang, Yang, Joy C., Ok, Joon-ha, Mack, Philip C., Kung, Hsing-Jien, Evans, Christopher P.

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