A machine learning approach for predicting CRISPR-Cas9 cleavage efficiencies and patterns underlying its mechanism of action von Abadi, Shiran, Yan, Winston X, Amar, David, Mayrose, Itay

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Crystal Structure of Staphylococcus aureus Cas9 von Nishimasu, Hiroshi, Cong, Le, Yan, Winston X., Ran, F. Ann, Zetsche, Bernd, Li, Yinqing, Kurabayashi, Arisa, Ishitani, Ryuichiro, Zhang, Feng, Nureki, Osamu

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Rationally engineered Cas9 nucleases with improved specificity von Slaymaker, Ian M., Gao, Linyi, Zetsche, Bernd, Scott, David A., Yan, Winston X., Zhang, Feng

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Cas13d Is a Compact RNA-Targeting Type VI CRISPR Effector Positively Modulated by a WYL-Domain-Containing Accessory Protein von Yan, Winston X., Chong, Shaorong, Zhang, Huaibin, Makarova, Kira S., Koonin, Eugene V., Cheng, David R., Scott, David A.

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In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy von Nelson, Christopher E., Hakim, Chady H., Ousterout, David G., Thakore, Pratiksha I., Moreb, Eirik A., Rivera, Ruth M. Castellanos, Madhavan, Sarina, Pan, Xiufang, Ran, F. Ann, Yan, Winston X., Asokan, Aravind, Zhang, Feng, Duan, Dongsheng, Gersbach, Charles A.

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In vivo gene editing in dystrophic mouse muscle and muscle stem cells von Tabebordbar, Mohammadsharif, Zhu, Kexian, Cheng, Jason K. W., Chew, Wei Leong, Widrick, Jeffrey J., Yan, Winston X., Maesner, Claire, Wu, Elizabeth Y., Xiao, Ru, Ran, F. Ann, Le Cong, Zhang, Feng, Vandenberghe, Luk H., Church, George M., Wagers, Amy J.

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BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks von Yan, Winston X., Mirzazadeh, Reza, Garnerone, Silvano, Scott, David, Schneider, Martin W., Kallas, Tomasz, Custodio, Joaquin, Wernersson, Erik, Li, Yinqing, Gao, Linyi, Federova, Yana, Zetsche, Bernd, Zhang, Feng, Bienko, Magda, Crosetto, Nicola

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Functionally diverse type V CRISPR-Cas systems von Yan, Winston X, Hunnewell, Pratyusha, Alfonse, Lauren E, Carte, Jason M, Keston-Smith, Elise, Sothiselvam, Shanmugapriya, Garrity, Anthony J, Chong, Shaorong, Makarova, Kira S, Koonin, Eugene V, Cheng, David R, Scott, David A

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Engineered Cpf1 variants with altered PAM specificities von Gao, Linyi, Cox, David B T, Yan, Winston X, Manteiga, John C, Schneider, Martin W, Yamano, Takashi, Nishimasu, Hiroshi, Nureki, Osamu, Crosetto, Nicola, Zhang, Feng

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CRISPR–Cas in mobile genetic elements: counter-defence and beyond von Faure, Guilhem, Shmakov, Sergey A., Yan, Winston X., Cheng, David R., Scott, David A., Peters, Joseph E., Makarova, Kira S., Koonin, Eugene V.

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The miniature CRISPR-Cas12m effector binds DNA to block transcription von Wu, Wen Y., Mohanraju, Prarthana, Liao, Chunyu, Adiego-Pérez, Belén, Creutzburg, Sjoerd C.A., Makarova, Kira S., Keessen, Karlijn, Lindeboom, Timon A., Khan, Tahseen S., Prinsen, Stijn, Joosten, Rob, Yan, Winston X., Migur, Anzhela, Laffeber, Charlie, Scott, David A., Lebbink, Joyce H.G., Koonin, Eugene V., Beisel, Chase L., van der Oost, John

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Engineered Cas12i2 is a versatile high-efficiency platform for therapeutic genome editing von McGaw, Colin, Garrity, Anthony J., Munoz, Gabrielle Z., Haswell, Jeffrey R., Sengupta, Sejuti, Keston-Smith, Elise, Hunnewell, Pratyusha, Ornstein, Alexa, Bose, Mishti, Wessells, Quinton, Jakimo, Noah, Yan, Paul, Zhang, Huaibin, Alfonse, Lauren E., Ziblat, Roy, Carte, Jason M., Lu, Wei-Cheng, Cerchione, Derek, Hilbert, Brendan, Sothiselvam, Shanmugapriya, Yan, Winston X., Cheng, David R., Scott, David A., DiTommaso, Tia, Chong, Shaorong

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How to pay for individualized genetic medicines von Pian, Julia M. Y., Owusu, Nana, Vitarello, Julia, Yan, Winston X., Lo, Andrew W., Yu, Timothy W.

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Consensus Guidelines for the Design and In Vitro Preclinical Efficacy Testing N-of-1 Exon Skipping Antisense Oligonucleotides von Aartsma-Rus, Annemieke, Garanto, Alejandro, van Roon-Mom, Willeke, McConnell, Erin M, Suslovitch, Victoria, Yan, Winston X, Watts, Jonathan K, Yu, Timothy W

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A framework for N-of-1 trials of individualized gene-targeted therapies for genetic diseases von Kim-McManus, Olivia, Gleeson, Joseph G., Mignon, Laurence, Smith Fine, Amena, Yan, Winston, Nolen, Nicole, Demarest, Scott, Berry-Kravis, Elizabeth, Finkel, Richard, Leonard, Stefanie, Finlayson, Samuel, Augustine, Erika, Lyon, Gholson J., Schule, Rebecca, Yu, Timothy

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Reducing the gradient artefact in simultaneous EEG-fMRI by adjusting the subject's axial position von Mullinger, Karen J., Yan, Winston X., Bowtell, Richard

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In vivo genome editing using Staphylococcus aureus Cas9 von Ran, F. Ann, Cong, Le, Yan, Winston X., Scott, David A., Gootenberg, Jonathan S., Kriz, Andrea J., Zetsche, Bernd, Shalem, Ophir, Wu, Xuebing, Makarova, Kira S., Koonin, Eugene V., Sharp, Phillip A., Zhang, Feng

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Physical modeling of pulse artefact sources in simultaneous EEG/fMRI von Yan, Winston X., Mullinger, Karen J., Geirsdottir, Gerda B., Bowtell, Richard

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Understanding gradient artefacts in simultaneous EEG/fMRI von Yan, Winston X., Mullinger, Karen J., Brookes, Matt J., Bowtell, Richard

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Diversity and evolution of class 2 CRISPR–Cas systems von Shmakov, Sergey, Smargon, Aaron, Scott, David, Cox, David, Pyzocha, Neena, Yan, Winston, Abudayyeh, Omar O., Gootenberg, Jonathan S., Makarova, Kira S., Wolf, Yuri I., Severinov, Konstantin, Zhang, Feng, Koonin, Eugene V.

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