Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks von Lee, Michael J., Ye, Albert S., Gardino, Alexandra K., Heijink, Anne Margriet, Sorger, Peter K., MacBeath, Gavin, Yaffe, Michael B.

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Why geneticists stole cancer research even though cancer is primarily a signaling disease von Yaffe, Michael B

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Tissue plasminogen activator (tPA) treatment for COVID‐19 associated acute respiratory distress syndrome (ARDS): A case series von Wang, Janice, Hajizadeh, Negin, Moore, Ernest E., McIntyre, Robert C., Moore, Peter K., Veress, Livia A., Yaffe, Michael B., Moore, Hunter B., Barrett, Christopher D.

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Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response von Reinhardt, H. Christian, Yaffe, Michael B.

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ISTH interim guidance on recognition and management of coagulopathy in COVID‐19: A comment von Barrett, Christopher D., Moore, Hunter B., Yaffe, Michael B., Moore, Ernest E.

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Multi-pathway DNA-repair reporters reveal competition between end-joining, single-strand annealing and homologous recombination at Cas9-induced DNA double-strand breaks von van de Kooij, Bert, Kruswick, Alex, van Attikum, Haico, Yaffe, Michael B.

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BRD4 prevents the accumulation of R-loops and protects against transcription–replication collision events and DNA damage von Lam, Fred C., Kong, Yi Wen, Huang, Qiuying, Vu Han, Tu-Lan, Maffa, Amanda D., Kasper, Ekkehard M., Yaffe, Michael B.

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Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targeted nanoparticles von Lam, Fred C., Morton, Stephen W., Wyckoff, Jeffrey, Vu Han, Tu-Lan, Hwang, Mun Kyung, Maffa, Amanda, Balkanska-Sinclair, Elena, Yaffe, Michael B, Floyd, Scott R, Hammond, Paula T

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Chemical Genetic Screen for AMPKα2 Substrates Uncovers a Network of Proteins Involved in Mitosis von Banko, Max R., Allen, Jasmina J., Schaffer, Bethany E., Wilker, Erik W., Tsou, Peiling, White, Jamie L., Villén, Judit, Wang, Beatrice, Kim, Sara R., Sakamoto, Kei, Gygi, Steven P., Cantley, Lewis C., Yaffe, Michael B., Shokat, Kevan M., Brunet, Anne

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Protein Regulation in Signal Transduction von Lee, Michael J, Yaffe, Michael B

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Computational approaches for analyzing information flow in biological networks von Kholodenko, Boris, Yaffe, Michael B, Kolch, Walter

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Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2 von Reinhardt, H Christian, Yaffe, Michael B

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The scientific drunk and the lamppost: massive sequencing efforts in cancer discovery and treatment von Yaffe, Michael B

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RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly von Huen, Michael S.Y., Grant, Robert, Manke, Isaac, Minn, Kay, Yu, Xiaochun, Yaffe, Michael B., Chen, Junjie

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Pyruvate Kinase Isoform Expression Alters Nucleotide Synthesis to Impact Cell Proliferation von Lunt, Sophia Y., Muralidhar, Vinayak, Hosios, Aaron M., Israelsen, William J., Gui, Dan Y., Newhouse, Lauren, Ogrodzinski, Martin, Hecht, Vivian, Xu, Kali, Acevedo, Paula N. Marín, Hollern, Daniel P., Bellinger, Gary, Dayton, Talya L., Christen, Stefan, Elia, Ilaria, Dinh, Anh T., Stephanopoulos, Gregory, Manalis, Scott R., Yaffe, Michael B., Andrechek, Eran R., Fendt, Sarah-Maria, Vander Heiden, Matthew G.

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Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma von Braun, Christian J., Stanciu, Monica, Boutz, Paul L., Patterson, Jesse C., Calligaris, David, Higuchi, Fumi, Neupane, Rachit, Fenoglio, Silvia, Cahill, Daniel P., Wakimoto, Hiroaki, Agar, Nathalie Y.R., Yaffe, Michael B., Sharp, Phillip A., Hemann, Michael T., Lees, Jacqueline A.

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Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output von Miller, Chad J, Lou, Hua Jane, Simpson, Craig, van de Kooij, Bert, Ha, Byung Hak, Fisher, Oriana S, Pirman, Natasha L, Boggon, Titus J, Rinehart, Jesse, Yaffe, Michael B, Linding, Rune, Turk, Benjamin E

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The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response von Niedelman, Wendy, Gold, Daniel A, Rosowski, Emily E, Sprokholt, Joris K, Lim, Daniel, Farid Arenas, Ailan, Melo, Mariane B, Spooner, Eric, Yaffe, Michael B, Saeij, Jeroen P J

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MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis von Suarez-Lopez, Lucia, Sriram, Ganapathy, Kong, Yi Wen, Morandell, Sandra, Merrick, Karl A., Hernandez, Yuliana, Haigis, Kevin M., Yaffe, Michael B.

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The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling von Hsu, Peggy P., Kang, Seong A., Rameseder, Jonathan, Zhang, Yi, Ottina, Kathleen A., Lim, Daniel, Peterson, Timothy R., Choi, Yongmun, Gray, Nathanael S., Yaffe, Michael B., Marto, Jarrod A., Sabatini, David M.

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