Discovery of DS34942424: An orally potent analgesic without mu opioid receptor agonist activity von Arita, Tsuyoshi, Asano, Masayoshi, Kubota, Kazufumi, Domon, Yuki, Machinaga, Nobuo, Shimada, Kousei

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Analgesic effects of mirogabalin, a novel ligand for α2δ subunit of voltage-gated calcium channels, in experimental animal models of fibromyalgia von Saeki, Kensuke, Yasuda, Shun-ichi, Kato, Masami, Kano, Mayumi, Domon, Yuki, Arakawa, Naohisa, Kitano, Yutaka

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Discovery of a Novel Class of State-Dependent NaV1.7 Inhibitors for the Treatment of Neuropathic Pain von Tanaka, Kyosuke, Kobayashi, Hiroyuki, Suzuki, Sayaka, Shibuya, Satoshi, Kimoto, Hiroko, Domon, Yuki, Kubota, Kazufumi, Kitano, Yutaka, Yokoyama, Tomihisa, Shimizugawa, Akiko, Koishi, Ryuta, Fujiwara, Chie, Asano, Daigo, Shinozuka, Tsuyoshi

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Infantile Pain Episodes Associated with Novel Nav1.9 Mutations in Familial Episodic Pain Syndrome in Japanese Families von Okuda, Hiroko, Noguchi, Atsuko, Kobayashi, Hatasu, Kondo, Daiki, Harada, Kouji H, Youssefian, Shohab, Shioi, Hirotomo, Kabata, Risako, Domon, Yuki, Kubota, Kazufumi, Kitano, Yutaka, Takayama, Yasunori, Hitomi, Toshiaki, Ohno, Kousaku, Saito, Yoshiaki, Asano, Takeshi, Tominaga, Makoto, Takahashi, Tsutomu, Koizumi, Akio

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Binding Characteristics and Analgesic Effects of Mirogabalin, a Novel Ligand for the α2δ Subunit of Voltage-Gated Calcium Channels von Domon, Yuki, Arakawa, Naohisa, Inoue, Tatsuya, Matsuda, Fumihiko, Takahashi, Makoto, Yamamura, Naotoshi, Kai, Kiyonori, Kitano, Yutaka

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Discovery of (phenoxy-2-hydroxypropyl)piperidines as a novel class of voltage-gated sodium channel 1.7 inhibitors von Suzuki, Sayaka, Kuroda, Takeshi, Kimoto, Hiroko, Domon, Yuki, Kubota, Kazufumi, Kitano, Yutaka, Yokoyama, Tomihisa, Shimizugawa, Akiko, Sugita, Ryusuke, Koishi, Ryuta, Asano, Daigo, Tamaki, Kazuhiko, Shinozuka, Tsuyoshi, Kobayashi, Hiroyuki

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Improvement in social anxiety following a return-to-work intervention for patients with depression von Okamoto, Yoko, Takanashi, Rieko, Sutoh, Chihiro, Domon, Yuki, Yamada, Mayuko, Baba, Yoko, Aya, Chiaki, Yamanouchi, Naoto, Sasaki, Hajime, Shimizu, Eiji

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Role of Angiotensin II Type 1 Receptor on Retinal Vascular Leakage in a Rat Oxygen-Induced Retinopathy Model von Nakamura, Hiroaki, Yamazaki, Mami, Ohyama, Takao, Inoue, Tatsuya, Arakawa, Naohisa, Domon, Yuki, Yokoyama, Tomihisa

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Discovery of a novel bicyclic compound, DS54360155, as an orally potent analgesic without mu-opioid receptor agonist activity von Arita, Tsuyoshi, Asano, Masayoshi, Kubota, Kazufumi, Domon, Yuki, Machinaga, Nobuo, Shimada, Kousei

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Discovery of conolidine derivative DS39201083 as a potent novel analgesic without mu opioid agonist activity von Arita, Tsuyoshi, Asano, Masayoshi, Kubota, Kazufumi, Domon, Yuki, Machinaga, Nobuo, Shimada, Kousei

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Anxiolytic-like effects of mirogabalin, a novel ligand for α2δ ligand of voltage-gated calcium channels, in rats repeatedly injected with acidic saline intramuscularly, as an exper... von Murasawa, Hiroyasu, Kobayashi, Hiroyuki, Yasuda, Shun-ichi, Saeki, Kensuke, Domon, Yuki, Arakawa, Naohisa, Kubota, Kazufumi, Kitano, Yutaka

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A novel [5.2.1]bicyclic amine is a potent analgesic without µ opioid activity von Noguchi, Tetsuji, Umezaki, Yuma, Takano, Rieko, Fujimoto, Teppei, Domon, Yuki, Kubota, Kazufumi, Ueda, Kenjiro, Kawase, Yumi, Yabe, Koichi, Yokoyama, Miki, Shimada, Kousei

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Binding characteristics and analgesic effects of mirogabalin, a novel ligand for the α 2 δ subunit of voltage-gated calcium channels von Domon, Yuki, Arakawa, Naohisa, Inoue, Tatsuya, Matsuda, Fumihiko, Takahashi, Makoto, Yamamura, Naotoshi, Kai, Kiyonori, Kitano, Yutaka

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Discovery of DS-1971a, a Potent, Selective NaV1.7 Inhibitor von Shinozuka, Tsuyoshi, Kobayashi, Hiroyuki, Suzuki, Sayaka, Tanaka, Kyosuke, Karanjule, Narayan, Hayashi, Noriyuki, Tsuda, Toshifumi, Tokumaru, Eri, Inoue, Masahiro, Ueda, Kiyono, Kimoto, Hiroko, Domon, Yuki, Takahashi, Sakiko, Kubota, Kazufumi, Yokoyama, Tomihisa, Shimizugawa, Akiko, Koishi, Ryuta, Fujiwara, Chie, Asano, Daigo, Sakakura, Tomoko, Takasuna, Kiyoshi, Abe, Yasuyuki, Watanabe, Toshiyuki, Kitano, Yutaka

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Anxiolytic-like effects of mirogabalin, a novel ligand for α 2 δ ligand of voltage-gated calcium channels, in rats repeatedly injected with acidic saline intramuscularly, as an exp... von Murasawa, Hiroyasu, Kobayashi, Hiroyuki, Yasuda, Shun-Ichi, Saeki, Kensuke, Domon, Yuki, Arakawa, Naohisa, Kubota, Kazufumi, Kitano, Yutaka

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N‑Aryl Indoles as a Novel Class of Potent NaV1.7 Inhibitors von Karanjule, Narayan, Hayashi, Noriyuki, Suzuki, Sayaka, Tsuda, Toshifumi, Tokumaru, Eri, Tanaka, Kyosuke, Kimoto, Hiroko, Domon, Yuki, Takahashi, Sakiko, Kubota, Kazufumi, Kitano, Yutaka, Yokoyama, Tomihisa, Koishi, Ryuta, Fujiwara, Chie, Inaba, Shinichi, Asano, Daigo, Sakakura, Tomoko, Takasuna, Kiyoshi, Shinozuka, Tsuyoshi

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N -Aryl Indoles as a Novel Class of Potent Na V 1.7 Inhibitors von Karanjule, Narayan, Hayashi, Noriyuki, Suzuki, Sayaka, Tsuda, Toshifumi, Tokumaru, Eri, Tanaka, Kyosuke, Kimoto, Hiroko, Domon, Yuki, Takahashi, Sakiko, Kubota, Kazufumi, Kitano, Yutaka, Yokoyama, Tomihisa, Koishi, Ryuta, Fujiwara, Chie, Inaba, Shinichi, Asano, Daigo, Sakakura, Tomoko, Takasuna, Kiyoshi, Shinozuka, Tsuyoshi

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Alkylsulfanyl analogs as potent α 2 δ ligands von Shimada, Kousei, Ohata, Yasuo, Kobayashi, Jun, Onishi, Yoshiyuki, Kawamura, Asuka, Domon, Yuki, Arakawa, Naohisa, Inoue, Tatsuya, Kitano, Yutaka, Matsuda, Fumihiko, Abe, Yuki, Deguchi, Tsuneo

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Alkylsulfanyl analogs as potent α2δ ligands von Shimada, Kousei, Ohata, Yasuo, Kobayashi, Jun, Onishi, Yoshiyuki, Kawamura, Asuka, Domon, Yuki, Arakawa, Naohisa, Inoue, Tatsuya, Kitano, Yutaka, Matsuda, Fumihiko, Abe, Yuki, Deguchi, Tsuneo

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Discovery of a Novel Class of State-Dependent Na V 1.7 Inhibitors for the Treatment of Neuropathic Pain von Tanaka, Kyosuke, Kobayashi, Hiroyuki, Suzuki, Sayaka, Shibuya, Satoshi, Kimoto, Hiroko, Domon, Yuki, Kubota, Kazufumi, Kitano, Yutaka, Yokoyama, Tomihisa, Shimizugawa, Akiko, Koishi, Ryuta, Fujiwara, Chie, Asano, Daigo, Shinozuka, Tsuyoshi

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