Disruption of CRAF-Mediated MEK Activation Is Required for Effective MEK Inhibition in KRAS Mutant Tumors von Lito, Piro, Saborowski, Anna, Yue, Jingyin, Solomon, Martha, Joseph, Eric, Gadal, Sunyana, Saborowski, Michael, Kastenhuber, Edward, Fellmann, Christof, Ohara, Kazuhiro, Morikami, Kenji, Miura, Takaaki, Lukacs, Christine, Ishii, Nobuya, Lowe, Scott, Rosen, Neal

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The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts von Beckedorff, Felipe, Blumenthal, Ezra, daSilva, Lucas Ferreira, Aoi, Yuki, Cingaram, Pradeep Reddy, Yue, Jingyin, Zhang, Anda, Dokaneheifard, Sadat, Valencia, Monica Guiselle, Gaidosh, Gabriel, Shilatifard, Ali, Shiekhattar, Ramin

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Integrator orchestrates RAS/ERK1/2 signaling transcriptional programs von Yue, Jingyin, Lai, Fan, Beckedorff, Felipe, Zhang, Anda, Pastori, Chiara, Shiekhattar, Ramin

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Complex roles of filamin-A mediated cytoskeleton network in cancer progression von Yue, Jingyin, Huhn, Steven, Shen, Zhiyuan

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TAF1 plays a critical role in AML1-ETO driven leukemogenesis von Xu, Ye, Man, Na, Karl, Daniel, Martinez, Concepcion, Liu, Fan, Sun, Jun, Martinez, Camilo Jose, Martin, Gloria Mas, Beckedorff, Felipe, Lai, Fan, Yue, Jingyin, Roisman, Alejandro, Greenblatt, Sarah, Duffort, Stephanie, Wang, Lan, Sun, Xiaojian, Figueroa, Maria, Shiekhattar, Ramin, Nimer, Stephen

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The Cytoskeleton Protein Filamin-A Is Required for an Efficient Recombinational DNA Double Strand Break Repair von JINGYIN YUE, QIN WANG, HUIMEI LU, BRENNEMAN, Mark, FEIYUE FAN, ZHIYUAN SHEN

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Inhibition of filamin-A reduces cancer metastatic potential von Jiang, Xi, Yue, Jingyin, Lu, Huimei, Campbell, Neil, Yang, Qifeng, Lan, Shijie, Haffty, Bruce G, Yuan, Changji, Shen, Zhiyuan

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Identification of the DNA repair defects in a case of Dubowitz syndrome von Yue, Jingyin, Lu, Huimei, Lan, Shijie, Liu, Jingmei, Stein, Mark N, Haffty, Bruce G, Shen, Zhiyuan

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Abrogation of the Transactivation Activity of p53 by BCCIP Down-regulation von Meng, Xiangbing, Yue, Jingyin, Liu, Zhihe, Shen, Zhiyuan

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Involvement of Caveolin-1 in repair of DNA damage through both homologous recombination and non-homologous end joining von Zhu, Hua, Yue, Jingyin, Pan, Zui, Wu, Hao, Cheng, Yan, Lu, Huimei, Ren, Xingcong, Yao, Ming, Shen, Zhiyuan, Yang, Jin-Ming

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Prognostic values of filamin-A status for topoisomerase II poison chemotherapy von Yue, Jingyin, Lan, Shijie, Yuan, Changji, Shen, Zhiyuan

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TAF1, the Largest Subunit of Tfiid, Is Dispensable for Adult Hematopoiesis von Liu, Fan, Yue, Jingyin, Tamiro, Francesco, Sun, Jun, Cingaram, Pradeepkumar Reddy, Hossack, Krystal Lisa, Caja, Concepcion Martinza, Beckedorff, Felipe, Shiekhattar, Ramin, Nimer, Stephen D.

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Deletion of Mouse Setd4 Promotes the Recovery of Hematopoietic Failure von Feng, Xing, Lu, Huimei, Yue, Jingyin, Shettigar, Megha, Liu, Jingmei, Denzin, Lisa K., Shen, Zhiyuan

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Targeted chemotherapy overcomes drug resistance in melanoma von Yue, Jingyin, Vendramin, Roberto, Liu, Fan, Lopez, Omar, Valencia, Monica G, Gomes Dos Santos, Helena, Gaidosh, Gabriel, Beckedorff, Felipe, Blumenthal, Ezra, Speroni, Lucia, Nimer, Stephen D, Marine, Jean-Christophe, Shiekhattar, Ramin

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Loss of Setd4 delays radiation-induced thymic lymphoma in mice von Feng, Xing, Lu, Huimei, Yue, Jingyin, Schneider, Neta, Liu, Jingmei, Denzin, Lisa K., Chan, Chang S., De, Subhajyoti, Shen, Zhiyuan

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Filamin-A as a marker and target for DNA damage based cancer therapy von Yue, Jingyin, Lu, Huimei, Liu, Jingmei, Berwick, Marianne, Shen, Zhiyuan

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Targeted Chemotherapy overcomes drug resistance in melanoma von Yue, Jingyin, Vendramin, Roberto, Liu, Fan, Lopez, Omar, Valencia, Monica G, Gomes Dos Santos, Helena, Gaidosh, Gabriel, Beckedorff, Felipe, Blumenthal, Ezra, Speroni, Lucia, Nimer, Stephen D, Marine, Jean-Christophe, Shiekhattar, Ramin

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Integrator enforces the fidelity of transcriptional termination at protein-coding genes von Dasilva, Lucas Ferreira, Blumenthal, Ezra, Beckedorff, Felipe, Cingaram, Pradeep Reddy, Gomes Dos Santos, Helena, Edupuganti, Raghu Ram, Zhang, Anda, Dokaneheifard, Sadat, Aoi, Yuki, Yue, Jingyin, Kirstein, Nina, Tayari, Mina Masoumeh, Shilatifard, Ali, Shiekhattar, Ramin

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Abstract 4758: Disruption of CRAF-mediated MEK activation is required for effective MEK inhibition in KRAS mutant tumors von Lito, Piro, Saborowski, Anna, Yue, Jingyin, Solomon, Martha, Joseph, Eric, Fellman, Christof, Ohara, Kazuhiro, Morikami, Kenji, Miura, Takaaki, Lucas, Christine, Ishii, Nobuya, Lowe, Scott, Rosen, Neal

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BCCIP regulates homologous recombination by distinct domains and suppresses spontaneous DNA damage von Lu, Huimei, Yue, Jingyin, Meng, Xiangbing, Nickoloff, Jac A, Shen, Zhiyuan

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