New Potent Antibacterial Oxazolidinone (MRX-I) with an Improved Class Safety Profile von Gordeev, Mikhail F, Yuan, Zhengyu Y

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A Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft tissue infe... von Zhao, Xu, Huang, Haihui, Yuan, Hong, Yuan, Zhengyu, Zhang, Yingyuan

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A Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft tissue infe... von Zhao, Xu, Huang, Haihui, Yuan, Hong, Yuan, Zhengyu, Zhang, Yingyuan

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Actinonin, a Naturally Occurring Antibacterial Agent, Is a Potent Deformylase Inhibitor von Chen, Dawn Z, Patel, Dinesh V, Hackbarth, Corinne J, Wang, Wen, Dreyer, Geoffrey, Young, Dennis C, Margolis, Peter S, Wu, Charlotte, Ni, Zi-Jie, Trias, Joaquim, White, Richard J, Yuan, Zhengyu

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Internetization and the markups of export firms: Evidence from China von Shen, Guobing, Shen, Binchao, Wu, Ruochen, Yuan, Zhengyu

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N-Alkyl Urea Hydroxamic Acids as a New Class of Peptide Deformylase Inhibitors with Antibacterial Activity von HACKBARTH, Corinne J, CHEN, Dawn Z, LOPEZ, S, WITHERS, George III, GU, Helen, DUNN, Elina, KULATHILA, R, PAN, Shi-Hao, PORTER, Wilma L, JACOBS, Jeff, TRIAS, Joaquim, PATEL, Dinesh V, LEWIS, Jason G, WEIDMANN, Beat, WHITE, Richard J, ZHENGYU YUAN, CLARK, Kirk, MANGOLD, James B, CRAMER, Jeffrey A, MARGOLIS, Peter S, WEN WANG, KOEHN, Jim, WU, Charlotte

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Proteomic Study of Peptide Deformylase Inhibition in Streptococcus pneumoniae and Staphylococcus aureus von Wang, Wen, White, Richard, Yuan, Zhengyu

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Peptide Deformylase in Staphylococcus aureus: Resistance to Inhibition Is Mediated by Mutations in the Formyltransferase Gene von Margolis, P S, Hackbarth, C J, Young, D C, Wang, W, Chen, D, Yuan, Z, White, R, Trias, J

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Role of the AcrAB-TolC Efflux Pump in Determining Susceptibility of Haemophilus influenzae to the Novel Peptide Deformylase Inhibitor LBM415 von DEAN, Charles R, NARAYAN, Shubha, RYDER, Neil S, DAIGLE, Denis M, DZINK-FOX, Joann L, XIAOLING PUYANG, BRACKEN, Kathryn R, DEAN, Karl E, WEIDMANN, Beat, ZHENGYU YUAN, JAIN, Rakesh

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Resistance of Streptococcus pneumoniae to deformylase inhibitors is due to mutations in defB von MARGOLIS, Peter, HACKBARTH, Corinne, LOPEZ, Sara, MANIAR, Mita, WEN WANG, ZHENGYU YUAN, WHITE, Richard, TRIAS, Joaquim

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Clinical Pharmacology and Utility of Contezolid in Chinese Patients with Complicated Skin and Soft-Tissue Infections von Yuan, Hong, Wu, Hailan, Zhang, Yingyuan, Huang, Haihui, Li, Yi, Wu, Junzhen, Cao, Guoying, Yu, Jicheng, Guo, Beining, Wu, Jufang, Yuan, Zhengyu, Chen, Yuancheng, Yang, Wanqiu, Wu, Xiaojie, Zhang, Jing

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Metabolism of MRX-I, a Novel Antibacterial Oxazolidinone, in Humans: The Oxidative Ring Opening of 2,3-Dihydropyridin-4-One Catalyzed by Non-P450 Enzymes von Meng, Jian, Zhong, Dafang, Li, Liang, Yuan, Zhengyu, Yuan, Hong, Xie, Cen, Zhou, Jialan, Li, Chen, Gordeev, Mikhail Fedorovich, Liu, Jinqian, Chen, Xiaoyan

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Deformylase as a novel antibacterial target von Yuan, Zhengyu, Trias, Joaquim, White, Richard J

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Poisson-Gumbel Model for Wind Speed Threshold Estimation of Maximum Wind Speed von Yu, Wenzheng, Gao, Yang, Yuan, Zhengyu, Yao, Xin, Zhu, Mingxuan, Zhang, Hanxiaoya

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Discovery of Antibacterial Contezolid Acefosamil: Innovative O‑Acyl Phosphoramidate Prodrug for IV and Oral Therapies von Liu, Jinqian, Wang, Wen, Wang, Changqing, Zhang, Li, Zhang, Xueliang, Liu, Shicong, Xu, Yunhua, Wang, Hailin, Dai, Qing, Liu, Chun, Wang, Xinghai, Yuan, Zhengyu, Gordeev, Mikhail F.

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N- and C-terminal modifications of negamycin von Raju, B, Mortell, Kathleen, Anandan, Sampathkumar, O'Dowd, Hardwin, Gao, Hongwu, Gomez, Marcela, Hackbarth, Corinne, Wu, Charlotte, Wang, Wen, Yuan, Zhengyu, White, Richard, Trias, Joaquim, Patel, Dinesh V

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Conformationally restricted analogs of deoxynegamycin von Raju, B., Anandan, Sampathkumar, Gu, Shihai, Herradura, Prudencio, O’Dowd, Hardwin, Kim, Bum, Gomez, Marcela, Hackbarth, Corinne, Wu, Charlotte, Wang, Wen, Yuan, Zhengyu, White, Richard, Trias, Joaquim, Patel, Dinesh V.

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Selection and characterisation of Staphylococcus aureus mutants with reduced susceptibility to the investigational oxazolidinone MRX-I von Huang, Yanqin, Xu, Yunhua, Liu, Shicong, Wang, Hailin, Xu, Xiaogang, Guo, Qinglan, Wu, Baixue, Gordeev, Mikhail F, Wang, Wen, Yuan, Zhengyu, Wang, Minggui

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A High-Density Screening Format for Encoded Combinatorial Libraries: Assay Miniaturization and Its Application to Enzymatic Reactions von Schullek, John R., Butler, John H., Ni, Zhi-Jie, Chen, Dawn, Yuan, Zhengyu

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The evolution of peptide deformylase as a target: Contribution of biochemistry, genetics and genomics von Yuan, Zhengyu, White, Richard J.

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