FGF21 Normalizes Plasma Glucose in Mouse Models of Type 1 Diabetes and Insulin Receptor Dysfunction von Diener, John L, Mowbray, Sarah, Huang, Waan-Jeng, Yowe, David, Xu, Jian, Caplan, Shari, Misra, Abhay, Kapur, Ankur, Shapiro, Jeffrey, Ke, Xiaoling, Wu, Xiaoping, Bose, Avirup, Panza, Darrell, Chen, Min, Beaulieu, Valerie, Gao, Jiaping

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Discovery and Characterization of Allosteric WNK Kinase Inhibitors von Yamada, Ken, Zhang, Ji-Hu, Xie, Xiaoling, Reinhardt, Juergen, Xie, Amy Qiongshu, LaSala, Daniel, Kohls, Darcy, Yowe, David, Burdick, Debra, Yoshisue, Hajime, Wakai, Hiromichi, Schmidt, Isabel, Gunawan, Jason, Yasoshima, Kayo, Yue, Q. Kimberley, Kato, Mitsunori, Mogi, Muneto, Idamakanti, Neeraja, Kreder, Natasha, Drueckes, Peter, Pandey, Pramod, Kawanami, Toshio, Huang, Waanjeng, Yagi, Yukiko I, Deng, Zhan, Park, Hyi-Man

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Secreted PCSK9 promotes LDL receptor degradation independently of proteolytic activity von Li, Jun, Tumanut, Christine, Gavigan, Julie-Ann, Huang, Waan-Jeng, Hampton, Eric N, Tumanut, Rachelle, Suen, Ka Fai, Trauger, John W, Spraggon, Glen, Lesley, Scott A, Liau, Gene, Yowe, David, Harris, Jennifer L

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Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands von Meingassner, Josef G., Aschauer, Heinrich, Winiski, Anthony P., Dales, Natalie, Yowe, David, Winther, Michael D., Zhang, Zaihui, Stütz, Anton, Billich, Andreas

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Mitochondrial Decay in Hepatocytes from Old Rats: Membrane Potential Declines, Heterogeneity and Oxidants Increase von Hagen, Tory M., Yowe, David L., Bartholomew, James C., Wehr, Carol M., Do, Katherine L., Jin-Y. Park, Ames, Bruce N.

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Identification of 2-{2-[2-(5-Bromo-2- methoxyphenyl)-ethyl]-3-fluorophenyl}-4,5-dihydro-1H-imidazole (ML00253764), a Small Molecule Melanocortin 4 Receptor Antagonist That Effectiv... von Vos, Tricia J, Caracoti, Andrei, Che, Jennifer L, Dai, Mingshi, Farrer, Cheryl A, Forsyth, Nancy E, Drabic, Stacey V, Horlick, Robert A, Lamppu, Diana, Yowe, David L, Balani, Suresh, Li, Ping, Zeng, Hang, Joseph, Ingrid B. J. K, Rodriguez, Luis E, Maguire, Martin P, Patane, Michael A, Claiborne, Christopher F

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Role of Regulator of G Protein Signaling 16 in Inflammation- Induced T Lymphocyte Migration and Activation von Lippert, Eric, Yowe, David L, Gonzalo, Jose-Angel, Justice, J. Paul, Webster, Jeremy M, Fedyk, Eric R, Hodge, Martin, Miller, Cheryl, Gutierrez-Ramos, Jose-Carlos, Borrego, Francisco, Keane-Myers, Andrea, Druey, Kirk M

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LLF580, an FGF21 Analog, Reduces Triglycerides and Hepatic Fat in Obese Adults With Modest Hypertriglyceridemia von Rader, Daniel J, Maratos-Flier, Eleftheria, Nguyen, Amanda, Hom, Doug, Ferriere, Michael, Li, Yifang, Kompa, Jill, Martic, Miljen, Hinder, Markus, Basson, Craig T, Yowe, David, Diener, John, Goldfine, Allison B

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New hypotheses about the structure-function of proprotein convertase subtilisin/kexin type 9: Analysis of the epidermal growth factor-like repeat A docking site using WaterMap von Pearlstein, Robert A., Hu, Qi-Ying, Zhou, Jing, Yowe, David, Levell, Julian, Dale, Bethany, Kaushik, Virendar K., Daniels, Doug, Hanrahan, Susan, Sherman, Woody, Abel, Robert

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Synthesis and biological evaluation of imidazole-based small molecule antagonists of the melanocortin 4 receptor (MC4-R) von MARSILJE, Thomas H, ROSES, Jonathan B, DANIELS, J. Scott, PING LI, LIJUN WU, PATANE, Michael A, CLAIBORNE, Christopher F, CALDERWOOD, Emily F, STROUD, Stephen G, FORSYTH, Nancy E, BLACKBURN, Christopher, YOWE, David L, MIAO, Wenyan, DRABIC, Stacey V, BOHANE, Marie D

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Small-molecule WNK inhibition regulates cardiovascular and renal function von Yamada, Ken, Park, Hyi-Man, Rigel, Dean F, DiPetrillo, Keith, Whalen, Erin J, Anisowicz, Anthony, Beil, Michael, Berstler, James, Brocklehurst, Cara Emily, Burdick, Debra A, Caplan, Shari L, Capparelli, Michael P, Chen, Guanjing, Chen, Wei, Dale, Bethany, Deng, Lin, Fu, Fumin, Hamamatsu, Norio, Harasaki, Kouki, Herr, Tracey, Hoffmann, Peter, Hu, Qi-Ying, Huang, Waan-Jeng, Idamakanti, Neeraja, Imase, Hidetomo, Iwaki, Yuki, Jain, Monish, Jeyaseelan, Jey, Kato, Mitsunori, Kaushik, Virendar K, Kohls, Darcy, Kunjathoor, Vidya, LaSala, Daniel, Lee, Jongchan, Liu, Jing, Luo, Yang, Ma, Fupeng, Mo, Ruowei, Mowbray, Sarah, Mogi, Muneto, Ossola, Flavio, Pandey, Pramod, Patel, Sejal J, Raghavan, Swetha, Salem, Bahaa, Shanado, Yuka H, Trakshel, Gary M, Turner, Gordon, Wakai, Hiromichi, Wang, Chunhua, Weldon, Stephen, Wielicki, Jennifer B, Xie, Xiaoling, Xu, Lingfei, Yagi, Yukiko I, Yasoshima, Kayo, Yin, Jianning, Yowe, David, Zhang, Ji-Hu, Zheng, Gang, Monovich, Lauren

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Identification and structure–activity relationships of a new series of Melanocortin-4 receptor antagonists von Vos, Tricia J., Balani, Suresh, Blackburn, Christopher, Chau, Ryan W., Danca, M. Diana, Drabic, Stacey V., Farrer, Cheryl A., Patane, Michael A., Stroud, Stephen G., Yowe, David L., Claiborne, Christopher F.

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Quantitation of age-related mitochondrial DNA deletions in rat tissues shows that their pattern of accumulation differs from that of humans von Yowe, David L, Ames, Bruce N

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Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models von Yamada, Ken, Levell, Julian, Yoon, Taeyong, Kohls, Darcy, Yowe, David, Rigel, Dean F, Imase, Hidetomo, Yuan, Jun, Yasoshima, Kayo, DiPetrillo, Keith, Monovich, Lauren, Xu, Lingfei, Zhu, Meicheng, Kato, Mitsunori, Jain, Monish, Idamakanti, Neeraja, Taslimi, Paul, Kawanami, Toshio, Argikar, Upendra A, Kunjathoor, Vidya, Xie, Xiaoling, Yagi, Yukiko I, Iwaki, Yuki, Robinson, Zachary, Park, Hyi-Man

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Cloning of the barramundi growth hormone-encoding gene: a comparative analysis of higher and lower vertebrate GH genes von Yowe, David L., Epping, Ronald J.

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Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease von Dorsch, Marion, Zheng, Gang, Yowe, David, Rao, Prakash, Wang, Yanjun, Shen, Qiong, Murphy, Curran, Xiong, Ximing, Shi, Qiuju, Gutierrez-Ramos, Jose-Carlos, Fraser, Chris, Villeval, Jean-Luc

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RGS18 is a myeloerythroid lineage-specific regulator of G-protein-signalling molecule highly expressed in megakaryocytes von Yowe, D, Weich, N, Prabhudas, M, Poisson, L, Errada, P, Kapeller, R, Yu, K, Faron, L, Shen, M, Cleary, J, Wilkie, T M, Gutierrez-Ramos, C, Hodge, M R

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FGF21 MIMETIC ANTIBODIES AND USES THEREOF von CEBE, Regis, OLLAND, Stephane, YOWE, David Langdon

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Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease von Dorsch, Marion, Zheng, Gang, Yowe, David, Rao, Prakash, Wang, Yanjun, Shen, Qiong, Murphy, Curran, Xiong, Ximing, Shi, Qiuju, Gutierrez-Ramos, Jose-Carlos, Fraser, Chris, Villeval, Jean-Luc

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FGF21 mimetic antibodies and uses thereof von Olland, Stephane, Cebe, Regis, Yowe, David Langdon

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