Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1 von Yousef, Hanadie, Czupalla, Cathrin J., Lee, Davis, Chen, Michelle B., Burke, Ashley N., Zera, Kristy A., Zandstra, Judith, Berber, Elisabeth, Lehallier, Benoit, Mathur, Vidhu, Nair, Ramesh V., Bonanno, Liana N., Yang, Andrew C., Peterson, Todd, Hadeiba, Husein, Merkel, Taylor, Körbelin, Jakob, Schwaninger, Markus, Buckwalter, Marion S., Quake, Stephen R., Butcher, Eugene C., Wyss-Coray, Tony

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Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues von Chen, Michelle B., Yang, Andrew C., Yousef, Hanadie, Lee, Davis, Chen, Winnie, Schaum, Nicholas, Lehallier, Benoit, Quake, Stephen R., Wyss-Coray, Tony

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Age‐Associated Increase in BMP Signaling Inhibits Hippocampal Neurogenesis von Yousef, Hanadie, Morgenthaler, Adam, Schlesinger, Christina, Bugaj, Lukasz, Conboy, Irina M., Schaffer, David V.

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Inhibition and Role of let-7d in Idiopathic Pulmonary Fibrosis von PANDIT, Kusum V, CORCORAN, David, RICHARDS, Thomas, SELMAN, Moises, WATKINS, Simon C, PARDO, Annie, BEN-YEHUDAH, Ahmi, BOUROS, Demosthenes, EICKELBERG, Oliver, RAY, Prabir, BENOS, Panayiotis V, KAMINSKI, Naftali, YOUSEF, Hanadie, YARLAGADDA, Manohar, TZOUVELEKIS, Argyris, GIBSON, Kevin F, KONISHI, Kazuhisa, YOUSEM, Samuel A, SINGH, Mandal, HANDLEY, Daniel

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Undulating changes in human plasma proteome profiles across the lifespan von Lehallier, Benoit, Gate, David, Schaum, Nicholas, Nanasi, Tibor, Lee, Song Eun, Yousef, Hanadie, Moran Losada, Patricia, Berdnik, Daniela, Keller, Andreas, Verghese, Joe, Sathyan, Sanish, Franceschi, Claudio, Milman, Sofiya, Barzilai, Nir, Wyss-Coray, Tony

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Let-7d microRNA affects mesenchymal phenotypic properties of lung fibroblasts von Huleihel, Luai, Ben-Yehudah, Ahmi, Milosevic, Jadranka, Yu, Guoying, Pandit, Kusum, Sakamoto, Koji, Yousef, Hanadie, LeJeune, Megan, Coon, Tiffany A, Redinger, Carrie J, Chensny, Lara, Manor, Ester, Schatten, Gerald, Kaminski, Naftali

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Papain-based Single Cell Isolation of Primary Murine Brain Endothelial Cells Using Flow Cytometry von Yousef, Hanadie, Czupalla, Cathrin J, Lee, Davis, Butcher, Eugene C, Wyss-Coray, Tony

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Collagenase-based Single Cell Isolation of Primary Murine Brain Endothelial Cells Using Flow Cytometry von Czupalla, Cathrin J, Yousef, Hanadie, Wyss-Coray, Tony, Butcher, Eugene C

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Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris von Schaum, Nicholas, Karkanias, Jim, Neff, Norma F., May, Andrew P., Quake, Stephen R., Wyss-Coray, Tony, Darmanis, Spyros, Batson, Joshua, Botvinnik, Olga, Chen, Michelle B., Chen, Steven, Green, Foad, Jones, Robert, Maynard, Ashley, Penland, Lolita, Pisco, Angela Oliveira, Sit, Rene V., Stanley, Geoffrey M., Webber, James T., Zanini, Fabio, Baghel, Ankit S, Bakerman, Isaac, Bansal, Ishita, Berdnik, Daniela, Bilen, Biter, Brownfield, Douglas, Cain, Corey, Cho, Min, Cirolia, Giana, Conley, Stephanie D., Darmanis, Spyros, Demers, Aaron, Demir, Kubilay, de Morree, Antoine, Divita, Tessa, du Bois, Haley, Dulgeroff, Laughing Bear Torrez, Ebadi, Hamid, Espinoza, F. Hernán, Fish, Matt, Gan, Qiang, George, Benson M., Gillich, Astrid, Genetiano, Geraldine, Gu, Xueying, Gulati, Gunsagar S., Hang, Yan, Hosseinzadeh, Shayan, Huang, Albin, Iram, Tal, Isobe, Taichi, Ives, Feather, Kao, Kevin S., Karnam, Guruswamy, Kershner, Aaron M., Kiss, Bernhard M., Kong, William, Kumar, Maya E., Lam, Jonathan, Lee, Davis P., Lee, Song E., Li, Guang, Li, Qingyun, Liu, Ling, Lo, Annie, Lu, Wan-Jin, Manjunath, Anoop, May, Kaia L., May, Oliver L., McKay, Marina, Metzger, Ross J., Mignardi, Marco, Min, Dullei, Nabhan, Ahmad N., Ng, Katharine M., Noh, Joseph, Patkar, Rasika, Peng, Weng Chuan, Puccinelli, Robert, Rulifson, Eric J., Sikandar, Shaheen S., Sinha, Rahul, Szade, Krzysztof, Tan, Weilun, Tato, Cristina, Tellez, Krissie, Travaglini, Kyle J., Tropini, Carolina, Waldburger, Lucas, van Weele, Linda J., Wosczyna, Michael N., Xiang, Jinyi, Xue, Soso, Youngyunpipatkul, Justin, Zardeneta, Macy E., Zhang, Fan, Zhou, Lu, oungyunpipatkul, Justin Y, Castro, Paola, Croote, Derek

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Abstract WP295: Blocking the VCAM1-VLA4 Axis Prevents Cognitive Decline in a Mouse Model of Infarct-Induced Neurodegeneration von Zera, Kristy A, Bradshaw, Karen, Hahn, Oliver, Foltz, Aulden, Zhu, Li, Peterson, Todd, Yousef, Hanadie, Lee, Davis, Aghaeepour, Nima, Wyss-Coray, Tony, Buckwalter, Marion S

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Systemic attenuation of the TGF-β pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal von Yousef, Hanadie, Conboy, Michael J, Morgenthaler, Adam, Schlesinger, Christina, Bugaj, Lukasz, Paliwal, Preeti, Greer, Christopher, Conboy, Irina M, Schaffer, David

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Targeting VCAM1 to reduce neuroinflammation in ischemia‐triggered vascular dementia von Zera, Kristy A, Peterson, Todd, Yousef, Hanadie, Lee, Davis, Wyss‐Coray, Tony, Buckwalter, Marion S

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Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age von Brigger, Daniel, Riether, Carsten, van Brummelen, Robin, Mosher, Kira I., Shiu, Alicia, Ding, Zhaoqing, Zbären, Noemi, Gasser, Pascal, Guntern, Pascal, Yousef, Hanadie, Castellano, Joseph M., Storni, Federico, Graff-Radford, Neill, Britschgi, Markus, Grandgirard, Denis, Hinterbrandner, Magdalena, Siegrist, Mark, Moullan, Norman, Hofstetter, Willy, Leib, Stephen L., Villiger, Peter M., Auwerx, Johan, Villeda, Saul A., Wyss-Coray, Tony, Noti, Mario, Eggel, Alexander

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UNDULATIONS OF THE PLASMA PROTEOME DEFINE DISTINCT STAGES OF HUMAN LIFESPAN AND REVEAL ACCELERATED AGING IN ALZHEIMER’S DISEASE von Lehallier, Benoit, Gate, David, Schaum, Nicholas, Nanasi, Tibor, Lee, Song Eun, Yousef, Hanadie, Berdnik, Daniela, Franceschi, Claudio, Wyss-Coray, Tony

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O5‐05‐05: UNDULATIONS OF THE PLASMA PROTEOME DEFINE DISTINCT STAGES OF HUMAN LIFESPAN AND REVEAL ACCELERATED AGING IN ALZHEIMER'S DISEASE von Lehallier, Benoit, Gate, David, Schaum, Nicholas, Nanasi, Tibor, Lee, Song Eun, Yousef, Hanadie, Berdnik, Daniela, Franceschi, Claudio, Wyss-Coray, Tony

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Undulating changes in human plasma proteome profiles across the lifespan are linked to disease von Lehallier, Benoit, Gate, David, Schaum, Nicholas, Nanasi, Tibor, Lee, Song Eun, Yousef, Hanadie, Losada, Patricia Moran, Berdnik, Daniela, Keller, Andreas, Verghese, Joe, Sathyan, Sanish, Franceschi, Claudio, Milman, Sofiya, Barzilai, Nir, Wyss‐Coray, Tony

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Undulating changes in human plasma proteome profiles across the lifespan are linked to disease: Biomarkers (non‐neuroimaging): Novel biomarkers von Lehallier, Benoit, Gate, David, Schaum, Nicholas, Nanasi, Tibor, Lee, Song Eun, Yousef, Hanadie, Losada, Patricia Moran, Berdnik, Daniela, Keller, Andreas, Verghese, Joe, Sathyan, Sanish, Franceschi, Claudio, Milman, Sofiya, Barzilai, Nir, Wyss‐Coray, Tony

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Embryonic anti-aging niche von Conboy, Irina M, Yousef, Hanadie, Conboy, Michael J

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Mechanisms of action of hESC-secreted proteins that enhance human and mouse myogenesis von Yousef, Hanadie, Conboy, Michael J, Mamiya, Hikaru, Zeiderman, Matthew, Schlesinger, Christina, Schaffer, David V, Conboy, Irina M

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hESC-secreted proteins can be enriched for multiple regenerative therapies by heparin-binding von Yousef, Hanadie, Conboy, Michael J, Li, Ju, Zeiderman, Matthew, Vazin, Tandis, Schlesinger, Christina, Schaffer, David V, Conboy, Irina M

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