Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: Part 2, optimization for blood pressure reduction in spontaneously hypertensive rats von GINN, John D, BOSANAC, Todd, SCHLYER, Sabine, SMITH, James D, TURNER, Michael R, WU, Frank, YOUNG, Erick R. R, CHEN, Rhonda, CYWIN, Charles, HICKEY, Eugene, KASHEM, Mohammed, KERR, Steven, KUGLER, Stanley, XIANG LI, PROKOPOWICZ, Anthony

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Novel cross-talk within the IKK family controls innate immunity von Clark, Kristopher, Peggie, Mark, Plater, Lorna, Sorcek, Ronald J, Young, Erick R R, Madwed, Jeffrey B, Hough, Joanne, McIver, Edward G, Cohen, Philip

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Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: Part 3, aryl substituted pyrrolidines von Bosanac, Todd, Hickey, Eugene R., Ginn, John, Kashem, Mohammed, Kerr, Steven, Kugler, Stanley, Li, Xiang, Olague, Alan, Schlyer, Sabine, Young, Erick R.R.

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Discovery of potent and selective PKC-θ inhibitors von Cywin, Charles L., Dahmann, Georg, Prokopowicz, Anthony S., Young, Erick R.R., Magolda, Ronald L., Cardozo, Mario G., Cogan, Derek A., DiSalvo, Darren, Ginn, John D., Kashem, Mohammed A., Wolak, John P., Homon, Carol A., Farrell, Thomas M., Grbic, Heather, Hu, Hanbo, Kaplita, Paul V., Liu, Lisa H., Spero, Denice M., Jeanfavre, Deborah D., O’Shea, Kathy M., White, Della M., Woska, Joseph R., Brown, Maryanne L.

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Identification of a novel class of succinyl-nitrile-based Cathepsin S inhibitors von Bekkali, Younes, Thomson, David S., Betageri, Raj, Emmanuel, Michel J., Hao, Ming-Hong, Hickey, Eugene, Liu, Weimin, Patel, Usha, Ward, Yancey D., Young, Erick R.R., Nelson, Richard, Kukulka, Alison, Brown, Maryanne L., Crane, Kathy, White, Della, Freeman, Dorothy M., Labadia, Mark E., Wildeson, Jessi, Spero, Denice M.

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BI 5700, a Selective Chemical Inhibitor of IκB Kinase 2, Specifically Suppresses Epithelial-Mesenchymal Transition and Metastasis in Mouse Models of Tumor Progression von Huber, Margit A, Maier, Harald J, Alacakaptan, Memetcan, Wiedemann, Eva, Braunger, Jürgen, Boehmelt, Guido, Madwed, Jeffrey B, Young, Erick R R, Marshall, Daniel R, Pehamberger, Hubert, Wirth, Thomas, Kraut, Norbert, Beug, Hartmut

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Substituted 2 H-isoquinolin-1-ones as potent Rho-kinase inhibitors: Part 2, optimization for blood pressure reduction in spontaneously hypertensive rats von Ginn, John D., Bosanac, Todd, Chen, Rhonda, Cywin, Charles, Hickey, Eugene, Kashem, Mohammed, Kerr, Steven, Kugler, Stanley, Li, Xiang, Prokopowicz, Anthony, Schlyer, Sabine, Smith, James D., Turner, Michael R., Wu, Frank, Young, Erick R.R.

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A Practical Synthesis of Pyrene-4,5-dione von Young, Erick R. R, Funk, Raymond L

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Vinyl and Alkynyl Pyrimidines as Michael Acceptors:  An Approach to a Cylindrospermopsin Substructure von Djung, Jane F, Hart, David J, Young, Erick R. R

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SUBSTITUTED 3-AMINO-THIENO[2,3-b]PYRIDINE-2-CARBOXYLIC ACID AMIDE COMPOUNDS AND PROCESSES FOR PREPARING AND THEIR USES von TURNER MICHAEL R, YOUNG ERICK R.R, GINN JOHN D, SORCEK RONALD J

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NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES von SPERO, DENICE M, HICKEY, EUGENE R, WARD, YANCEY D, LIU, WEIMIN, FRYE, LEAH L, YOUNG, ERICK R.R, EMMANUEL, MICHEL J, THOMSON, DAVID S, SUN, SANXING, MORWICK, TINA M

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CATHEPSIN S INHIBITORS von HICKEY, EUGENE R, LIU, WEIMIN, YOUNG, ERICK R.R, SUN, SANXING, WARD, YANCEY, D

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Cathepsin S inhibitors von YOUNG ERICK R.R, SUN SANXING, WARD YANCEY D, HICKEY EUGENE R, LIU WIEMEN

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Substituted 3-amino-thieno[2,3-b] pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses von YOUNG ERICK R.R, WU LIFEN, CIRILLO PIER F, LIU WEIMIN, MARSHALL DANIEL R, CHEN ZHIDONG, DISALVO DARREN

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Compounds useful as reversible inhibitors of cysteine proteases von YOUNG ERICK R.R, SPERO DENICE M, WARD YANCEY D, THOMSON DAVID S, LIU WEIMIN

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Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses von YOUNG ERICK R.R, WU LIFEN, CIRILLO PIER F, LIU WEIMIN, MARSHALL DANIEL R, CHEN ZHIDONG, DISALVO DARREN

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Pyrimidine derivatives useful as inhibitors of PKC-theta von CARDOZO MARIO G, DAHMANN GEORGE, YOUNG ERICK R.R, COGAN DEREK, SPERO DENICE M, CYWIN CHARLES L, PROKOPOWICZ ANTHONY S.III, GINN JOHN D, DISALVO DARREN

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SPIROHETEROCYCLIC NITRILES USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES von YOUNG ERICK R.R, SPERO DENICE M, SUN SANXING, WARD YANCEY D, BEKKALI YOUNES, THOMSON DAVID S, HICKEY EUGENE R, LIU WEIMIN, PATEL USHA R

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Compounds useful as reversible inhibitors of cysteine proteases von YOUNG ERICK R.R, SUN SANXING, WARD YANCEY D, BEKKALI YOUNES, THOMSON DAVID S, SPERO DENICE MARY, HICKEY EUGENE R, LIU WEIMIN, PATEL USHA R

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Novel compounds useful as reversible inhibitors of cysteine proteases von YOUNG ERICK R.R, SPERO DENICE M, SUN SANXING, WARD YANCEY D, BEKKALI YOUNES, THOMSON DAVID S, HICKEY EUGENE R, LIU WEIMIN, PATEL USHA R

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