Comparison of the cancer gene targeting and biochemical selectivities of all targeted kinase inhibitors approved for clinical use von Uitdehaag, Joost C M, de Roos, Jeroen A D M, van Doornmalen, Antoon M, Prinsen, Martine B W, de Man, Jos, Tanizawa, Yoshinori, Kawase, Yusuke, Yoshino, Kohichiro, Buijsman, Rogier C, Zaman, Guido J R

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Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy von Asakura, Masanori, Kitakaze, Masafumi, Takashima, Seiji, Liao, Yulin, Ishikura, Fuminobu, Yoshinaka, Tsuyoshi, Ohmoto, Hiroshi, Node, Koichi, Yoshino, Kohichiro, Ishiguro, Hiroshi, Asanuma, Hiroshi, Sanada, Shoji, Matsumura, Yasushi, Takeda, Hiroshi, Beppu, Shintaro, Tada, Michihiko, Hori, Masatsugu, Higashiyama, Shigeki

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Ectodomain Shedding of Epidermal Growth Factor Receptor Ligands Is Required for Keratinocyte Migration in Cutaneous Wound Healing von Tokumaru, Sho, Higashiyama, Shigeki, Endo, Takeshi, Nakagawa, Takatoshi, Miyagawa, Jun-ichiro, Yamamori, Katsumi, Hanakawa, Yasushi, Ohmoto, Hiroshi, Yoshino, Kohichiro, Shirakata, Yuji, Matsuzawa, Yuji, Hashimoto, Koji, Taniguchi, Naoyuki

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The mechanism of cleavage of EGFR ligands induced by inflammatory cytokines in gastric cancer cells von Tanida, Satoshi, Joh, Takashi, Itoh, Keisuke, Kataoka, Hiromi, Sasaki, Makoto, Ohara, Hirotaka, Nakazawa, Takahiro, Nomura, Tomoyuki, Kinugasa, Yumi, Ohmoto, Hiroshi, Ishiguro, Hiroshi, Yoshino, Kohichiro, Higashiyama, Shigeki, Itoh, Makoto

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Cutting Edge: IL-18-Transgenic Mice: In Vivo Evidence of a Broad Role for IL-18 in Modulating Immune Function von Hoshino, Tomoaki, Kawase, Yusuke, Okamoto, Masaki, Yokota, Koichi, Yoshino, Kohichiro, Yamamura, Ken-ichi, Miyazaki, Jun-ichi, Young, Howard A, Oizumi, Kotaro

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BCL6B Contributes to Ocular Vascular Diseases via Notch Signal Silencing von Tanaka, Miruto, Nakamura, Shinsuke, Sakaue, Tomohisa, Yamamoto, Takumi, Maekawa, Masashi, Nishinaka, Anri, Yasuda, Hiroto, Yunoki, Kaori, Sato, Yuji, Sawa, Masaaki, Yoshino, Kohichiro, Shimazawa, Masamitsu, Hatano, Masahiko, Tokuhisa, Takeshi, Higashiyama, Shigeki, Hara, Hideaki

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BCL6B (B-Cell CLL/Lymphoma 6 Member B Protein) Contributes to Ocular Vascular Diseases via Notch Signal Silencing von Tanaka, Miruto, Nakamura, Shinsuke, Sakaue, Tomohisa, Yamamoto, Takumi, Maekawa, Masashi, Nishinaka, Anri, Yasuda, Hiroto, Yunoki, Kaori, Sato, Yuji, Sawa, Masaaki, Yoshino, Kohichiro, Shimazawa, Masamitsu, Hatano, Masahiko, Tokuhisa, Takeshi, Higashiyama, Shigeki, Hara, Hideaki

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Extracellular Cleavage of Bullous Pemphigoid Antigen 180/Type XVII Collagen and Its Involvement in Hemidesmosomal Disassembly von Hirako, Yoshiaki, Yoshino, Kohichiro, Zillikens, Detlef, Owaribe, Katsushi

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New Strategy for Antedrug Application:  Development of Metalloproteinase Inhibitors as Antipsoriatic Drugs von Sawa, Masaaki, Tsukamoto, Takako, Kiyoi, Takao, Kurokawa, Kiriko, Nakajima, Fumio, Nakada, Yuichiro, Yokota, Koichi, Inoue, Yoshimasa, Kondo, Hirosato, Yoshino, Kohichiro

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Bone Malformations in Interleukin‐18 Transgenic Mice von Kawase, Yusuke, Hoshino, Tomoaki, Yokota, Koichi, Kuzuhara, Akemi, Nakamura, Masanori, Maeda, Yu, Nishiwaki, Eiji, Zenmyo, Michihisa, Hiraoka, Koji, Aizawa, Hisamichi, Yoshino, Kohichiro

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Limited Role for Interleukin-18 in the Host Protection Response to Pulmonary Infection with Pseudomonas aeruginosa in Mice von NAKASONE, Chikara, KAWAKAMI, Kazuyoshi, HOSHINO, Tomoaki, KAWASE, Yusuke, YOKOTA, Koichi, YOSHINO, Kohichiro, TAKEDA, Kiyoshi, AKIRA, Shizuo, SAITO, Atsushi

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Studies on Selectin Blocker. 1. Structure−Activity Relationships of Sialyl Lewis X Analogs von Ohmoto, Hiroshi, Nakamura, Kenji, Inoue, Tomomi, Kondo, Noriko, Inoue, Yoshimasa, Yoshino, Kohichiro, Kondo, Hirosato, Ishida, Hideharu, Kiso, Makoto, Hasegawa, Akira

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A Metalloproteinase Inhibitor Prevents Lethal Acute Graft-Versus-Host Disease in Mice von Hattori, Koichi, Hirano, Takao, Ushiyama, Chifuyu, Miyajima, Hiroaki, Yamakawa, Norifumi, Ebata, Tomohiko, Wada, Yukihisa, Ikeda, Shoji, Yoshino, Kohichiro, Tateno, Masatoshi, Oshimi, Kazuo, Kayagaki, Nobuhiko, Yagita, Hideo, Okumura, Ko

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Abstract 2849: Analysis of the cancer gene targeting of clinical kinase inhibitor drugs by combining cellular and biochemical profiling von Zaman, Guido J.R., Uitdehaag, Joost C.M., Buijsman, Rogier C., Roos, Jeroen A.D.M. de, Doornmalen, Antoon M. van, Prinsen, Martine B.W., Man, Jos de, Kawase, Yusuke, Tanizawa, Yoshinori, Yoshino, Kohichiro

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Studies on Selectin Blockers. 4. Structure−Function Relationships of Sulfated Sialyl Lewis X Hexasaccharide Ceramides toward E-, P-, and L-Selectin Binding von Yoshino, Kohichiro, Ohmoto, Hiroshi, Kondo, Noriko, Tsujishita, Hideki, Hiramatsu, Yasuyuki, Inoue, Yoshimasa, Kondo, Hirosato, Ishida, Hideharu, Kiso, Makoto, Hasegawa, Akira

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Azasugar-Based MMP/ADAM Inhibitors as Antipsoriatic Agents von Moriyama, Hideki, Tsukida, Takahiro, Inoue, Yoshimasa, Yokota, Kohichi, Yoshino, Kohichiro, Kondo, Hirosato, Miura, Nobuaki, Nishimura, Shin-Ichiro

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Identification and characterization of novel mouse and human ADAM33s with potential metalloprotease activity von Yoshinaka, Tsuyoshi, Nishii, Kazuhiro, Yamada, Kouji, Sawada, Hirohide, Nishiwaki, Eiji, Smith, Katherine, Yoshino, Kohichiro, Ishiguro, Hiroshi, Higashiyama, Shigeki

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Synthesis and Structure-Activity Relationships of Thienylcyanoguanidine Derivatives as Potassium Channel Openers von YOSHIZUMI, Kazuya, IKEDA, Shoji, NISHIMURA, Noriyasu, YOSHINO, Kohichiro

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New Type of Metalloproteinase Inhibitor:  Design and Synthesis of New Phosphonamide-Based Hydroxamic Acids von Sawa, Masaaki, Kiyoi, Takao, Kurokawa, Kiriko, Kumihara, Hiroshi, Yamamoto, Minoru, Miyasaka, Tomohiro, Ito, Yasuko, Hirayama, Ryoichi, Inoue, Tomomi, Kirii, Yasuyuki, Nishiwaki, Eiji, Ohmoto, Hiroshi, Maeda, Yu, Ishibushi, Etsuko, Inoue, Yoshimasa, Yoshino, Kohichiro, Kondo, Hirosato

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Contribution of IL-18 to Th1 Response and Host Defense Against Infection by Mycobacterium tuberculosis: A Comparative Study with IL-12p40 von Kinjo, Yuki, Kawakami, Kazuyoshi, Uezu, Kaori, Yara, Satomi, Miyagi, Kazuya, Koguchi, Yoshinobu, Hoshino, Tomoaki, Okamoto, Masaki, Kawase, Yusuke, Yokota, Koichi, Yoshino, Kohichiro, Takeda, Kiyoshi, Akira, Shizuo, Saito, Atsushi

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