Phase 1 Trial of a Therapeutic Anti–Yellow Fever Virus Human Antibody von Low, Jenny G, Ng, Justin H.J, Ong, Eugenia Z, Kalimuddin, Shirin, Wijaya, Limin, Chan, Yvonne F.Z, Ng, Dorothy H.L, Tan, Hwee-Cheng, Baglody, Anjali, Chionh, Yok-Hian, Lee, Debbie C.P, Budigi, Yadunanda, Sasisekharan, Ram, Ooi, Eng-Eong

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Reciprocal regulation of TORC signaling and tRNA modifications by Elongator enforces nutrient-dependent cell fate von Candiracci, Julie, Migeot, Valerie, Chionh, Yok-Hian, Bauer, Fanelie, Brochier, Thomas, Russell, Brandon, Shiozaki, Kazuhiro, Dedon, Peter, Hermand, Damien

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Three distinct 3-methylcytidine (m3C) methyltransferases modify tRNA and mRNA in mice and humans von Xu, Luang, Liu, Xinyu, Sheng, Na, Oo, Kyaw Soe, Liang, Junxin, Chionh, Yok Hian, Xu, Juan, Ye, Fuzhou, Gao, Yong-Gui, Dedon, Peter C., Fu, Xin-Yuan

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tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence von Chionh, Yok Hian, McBee, Megan, Babu, I. Ramesh, Hia, Fabian, Lin, Wenwei, Zhao, Wei, Cao, Jianshu, Dziergowska, Agnieszka, Malkiewicz, Andrzej, Begley, Thomas J., Alonso, Sylvie, Dedon, Peter C.

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Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry von Su, Dan, Chan, Clement T Y, Gu, Chen, Lim, Kok Seong, Chionh, Yok Hian, McBee, Megan E, Russell, Brandon S, Babu, I Ramesh, Begley, Thomas J, Dedon, Peter C

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Allosteric pyruvate kinase-based “logic gate” synergistically senses energy and sugar levels in Mycobacterium tuberculosis von Zhong, Wenhe, Cui, Liang, Goh, Boon Chong, Cai, Qixu, Ho, Peiying, Chionh, Yok Hian, Yuan, Meng, Sahili, Abbas El, Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D., Lescar, Julien, Dedon, Peter C.

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tRNA epitranscriptomics and biased codon are linked to proteome expression in Plasmodium falciparum von Ng, Chee Sheng, Sinha, Ameya, Aniweh, Yaw, Nah, Qianhui, Babu, Indrakanti Ramesh, Gu, Chen, Chionh, Yok Hian, Dedon, Peter C, Preiser, Peter R

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2'-O methylation of internal adenosine by flavivirus NS5 methyltransferase von Dong, Hongping, Chang, David C, Hua, Maggie Ho Chia, Lim, Siew Pheng, Chionh, Yok Hian, Hia, Fabian, Lee, Yie Hou, Kukkaro, Petra, Lok, Shee-Mei, Dedon, Peter C, Shi, Pei-Yong

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Induction of functional human macrophages from bone marrow promonocytes by M-CSF in humanized mice von Li, Yan, Chen, Qingfeng, Zheng, Dahai, Yin, Lu, Chionh, Yok Hian, Wong, Lan Hiong, Tan, Shu Qi, Tan, Thiam Chye, Chan, Jerry K Y, Alonso, Sylvie, Dedon, Peter C, Lim, Bing, Chen, Jianzhu

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Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa von Jaroensuk, Juthamas, Wong, Yee Hwa, Zhong, Wenhe, Liew, Chong Wai, Maenpuen, Somchart, Sahili, Abbas E, Atichartpongkul, Sopapan, Chionh, Yok Hian, Nah, Qianhui, Thongdee, Narumon, McBee, Megan E, Prestwich, Erin G, DeMott, Michael S, Chaiyen, Pimchai, Mongkolsuk, Skorn, Dedon, Peter C, Lescar, Julien, Fuangthong, Mayuree

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Facile metabolic reprogramming distinguishes mycobacterial adaptation to hypoxia and starvation: ketosis drives starvation-induced persistence in M. bovis BCG von Davis, Nick K., Chionh, Yok Hian, McBee, Megan E., Hia, Fabian, Ma, Duanduan, Cui, Liang, Sharaf, Mariam Lucila, Cai, Weiling Maggie, Jumpathong, Watthanachai, Levine, Stuart S., Alonso, Sylvie, Dedon, Peter C.

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Targeting the Bacterial Epitranscriptome for Antibiotic Development: Discovery of Novel tRNA-(N1G37) Methyltransferase (TrmD) Inhibitors von Zhong, Wenhe, Koay, Ann, Ngo, Anna, Li, Yan, Nah, Qianhui, Wong, Yee Hwa, Chionh, Yok Hian, Ng, Hui Qi, Koh-Stenta, Xiaoying, Poulsen, Anders, Foo, Klement, McBee, Megan, Choong, Meng Ling, El Sahili, Abbas, Kang, Congbao, Matter, Alex, Lescar, Julien, Hill, Jeffrey, Dedon, Peter

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Identification of N6,N6-dimethyladenosine in transfer RNA from Mycobacterium bovis Bacille Calmette-Guérin von Chan, Clement T Y, Chionh, Yok Hian, Ho, Chia-Hua, Lim, Kok Seong, Babu, I Ramesh, Ang, Emily, Wenwei, Lin, Alonso, Sylvie, Dedon, Peter C

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Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37‑N 1)‑Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism von Zhong, Wenhe, Pasunooti, Kalyan Kumar, Balamkundu, Seetharamsing, Wong, Yee Hwa, Nah, Qianhui, Gadi, Vinod, Gnanakalai, Shanmugavel, Chionh, Yok Hian, McBee, Megan E, Gopal, Pooja, Lim, Siau Hoi, Olivier, Nelson, Buurman, Ed T, Dick, Thomas, Liu, Chuan Fa, Lescar, Julien, Dedon, Peter C

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Methylation at position 32 of tRNA catalyzed by TrmJ alters oxidative stress response in Pseudomonas aeruginosa von Jaroensuk, Juthamas, Atichartpongkul, Sopapan, Chionh, Yok Hian, Wong, Yee Hwa, Liew, Chong Wai, McBee, Megan E, Thongdee, Narumon, Prestwich, Erin G, DeMott, Michael S, Mongkolsuk, Skorn, Dedon, Peter C, Lescar, Julien, Fuangthong, Mayuree

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A Platform for Discovery and Quantification of Modified Ribonucleosides in RNA: Application to Stress-Induced Reprogramming of tRNA Modifications von Cai, Weiling Maggie, Chionh, Yok Hian, Hia, Fabian, Gu, Chen, Kellner, Stefanie, McBee, Megan E, Ng, Chee Sheng, Pang, Yan Ling Joy, Prestwich, Erin G, Lim, Kok Seong, Babu, I Ramesh, Begley, Thomas J, Dedon, Peter C

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Rational Engineering and Characterization of an mAb that Neutralizes Zika Virus by Targeting a Mutationally Constrained Quaternary Epitope von Tharakaraman, Kannan, Watanabe, Satoru, Chan, Kuan Rong, Huan, Jia, Subramanian, Vidya, Chionh, Yok Hian, Raguram, Aditya, Quinlan, Devin, McBee, Megan, Ong, Eugenia Z., Gan, Esther S., Tan, Hwee Cheng, Tyagi, Anu, Bhushan, Shashi, Lescar, Julien, Vasudevan, Subhash G., Ooi, Eng Eong, Sasisekharan, Ram

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Pyruvate Kinase Regulates the Pentose-Phosphate Pathway in Response to Hypoxia in Mycobacterium tuberculosis von Zhong, Wenhe, Guo, Jingjing, Cui, Liang, Chionh, Yok Hian, Li, Kuohan, El Sahili, Abbas, Cai, Qixu, Yuan, Meng, Michels, Paul A.M., Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D., Mu, Yuguang, Lescar, Julien, Dedon, Peter C.

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Crystal structure and catalytic mechanism of the essential m 1 G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa von Jaroensuk, Juthamas, Wong, Yee Hwa, Zhong, Wenhe, Liew, Chong Wai, Maenpuen, Somchart, Sahili, Abbas E, Atichartpongkul, Sopapan, Chionh, Yok Hian, Nah, Qianhui, Thongdee, Narumon, McBee, Megan E, Prestwich, Erin G, DeMott, Michael S, Chaiyen, Pimchai, Mongkolsuk, Skorn, Dedon, Peter C, Lescar, Julien, Fuangthong, Mayuree

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A multidimensional platform for the purification of non-coding RNA species von Chionh, Yok Hian, Ho, Chia-Hua, Pruksakorn, Dumnoensun, Ramesh Babu, I, Ng, Chee Sheng, Hia, Fabian, McBee, Megan E, Su, Dan, Pang, Yan Ling Joy, Gu, Chen, Dong, Hongping, Prestwich, Erin G, Shi, Pei-Yong, Preiser, Peter Rainer, Alonso, Sylvie, Dedon, Peter C

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