Integrated Genomic Analysis of Hürthle Cell Cancer Reveals Oncogenic Drivers, Recurrent Mitochondrial Mutations, and Unique Chromosomal Landscapes von Ganly, Ian, Makarov, Vladimir, Deraje, Shyamprasad, Dong, YiYu, Reznik, Ed, Seshan, Venkatraman, Nanjangud, Gouri, Eng, Stephanie, Bose, Promita, Kuo, Fengshen, Morris, Luc G.T., Landa, Inigo, Carrillo Albornoz, Pedro Blecua, Riaz, Nadeem, Nikiforov, Yuri E., Patel, Kepal, Umbricht, Christopher, Zeiger, Martha, Kebebew, Electron, Sherman, Eric, Ghossein, Ronald, Fagin, James A., Chan, Timothy A.

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Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets von Chen, Ying-Bei, Xu, Jianing, Skanderup, Anders Jacobsen, Dong, Yiyu, Brannon, A. Rose, Wang, Lu, Won, Helen H., Wang, Patricia I., Nanjangud, Gouri J., Jungbluth, Achim A., Li, Wei, Ojeda, Virginia, Hakimi, A. Ari, Voss, Martin H., Schultz, Nikolaus, Motzer, Robert J., Russo, Paul, Cheng, Emily H., Giancotti, Filippo G., Lee, William, Berger, Michael F., Tickoo, Satish K., Reuter, Victor E., Hsieh, James J.

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Analysis of renal cancer cell lines from two major resources enables genomics-guided cell line selection von Sinha, Rileen, Winer, Andrew G., Chevinsky, Michael, Jakubowski, Christopher, Chen, Ying-Bei, Dong, Yiyu, Tickoo, Satish K., Reuter, Victor E., Russo, Paul, Coleman, Jonathan A., Sander, Chris, Hsieh, James J., Hakimi, A. Ari

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ΔNp63 Inhibits Oxidative Stress-Induced Cell Death, Including Ferroptosis, and Cooperates with the BCL-2 Family to Promote Clonogenic Survival von Wang, Gary X., Tu, Ho-Chou, Dong, Yiyu, Skanderup, Anders Jacobsen, Wang, Yufeng, Takeda, Shugaku, Ganesan, Yogesh Tengarai, Han, Song, Liu, Han, Hsieh, James J., Cheng, Emily H.

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PUMA and BIM are required for oncogene inactivation-induced apoptosis von Bean, Gregory R, Ganesan, Yogesh Tengarai, Dong, Yiyu, Takeda, Shugaku, Liu, Han, Chan, Po M, Huang, Yafen, Chodosh, Lewis A, Zambetti, Gerard P, Hsieh, James J-D, Cheng, Emily H-Y

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Molecular characterization of sarcomatoid clear cell renal cell carcinoma unveils new candidate oncogenic drivers von Malouf, Gabriel G., Flippot, Ronan, Dong, Yiyu, Dinatale, Renzo G., Chen, Ying-Bei, Su, Xiaoping, Compérat, Eva, Rouprêt, Morgan, Mano, Roy, Blum, Kyle A., Yao, Hui, Mouawad, Roger, Spano, Jean-Philippe, Khayat, David, Karam, Jose A., Ho, Thai H., Tickoo, Satish K., Russo, Paul, Hsieh, James J., Tannir, Nizar M., Hakimi, Abraham A.

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A Pharmacologic Inhibitor of the Protease Taspase1 Effectively Inhibits Breast and Brain Tumor Growth von CHEN, David Y, LEE, Yishan, OH, Kyoung J, KORSMEYER, Stanley J, HERMONE, Ann, GUSSIO, Richard, SHOEMAKER, Robert H, CHENG, Emily H.-Y, HSIEH, James J.-D, VAN TINE, Brian A, SEARLEMAN, Adam C, WESTERGARD, Todd D, HAN LIU, TU, Ho-Chou, TAKEDA, Shugaku, YIYU DONG, PIWNICA-WORMS, David R

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A dual-modal PET/near infrared fluorescent nanotag for long-term immune cell tracking von Harmsen, Stefan, Medine, Emin Ilker, Moroz, Maxim, Nurili, Fuad, Lobo, Jose, Dong, Yiyu, Turkekul, Mezruh, Pillarsetty, Naga Vara Kishore, Ting, Richard, Ponomarev, Vladimir, Akin, Oguz, Aras, Omer

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Obtaining and analysis of flanking sequences from T-DNA transformants of Arabidopsis von Qin, Genji, Kang, Dingming, Dong, Yiyu, Shen, Yunping, Zhang, Li, Deng, Xiaohui, Zhang, Yao, Li, Song, Chen, Nan, Niu, Weiran, Chen, Cong, Liu, Peicheng, Chen, Haodong, Li, Jigang, Ren, Yanfei, Gu, Hongya, Deng, XingWang, Qu, Li-Jia, Chen, Zhangliang

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Hyperpolarized MRI Visualizes Warburg Effects and Predicts Treatment Response to mTOR Inhibitors in Patient-Derived ccRCC Xenograft Models von Dong, Yiyu, Eskandari, Roozbeh, Ray, Chelsea, Granlund, Kristin L, Santos-Cunha, Lidia Dos, Miloushev, Vesselin Z, Tee, Sui Seng, Jeong, Sangmoo, Aras, Omer, Chen, Ying-Bei, Cheng, Emily H, Hsieh, James J, Keshari, Kayvan R

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Targeting the mTOR Pathway in Hurthle Cell Carcinoma Results in Potent Antitumor Activity von Dong, Yiyu, Gong, Yongxing, Kuo, Fengshen, Makarov, Vladimir, Reznik, Ed, Nanjangud, Gouri J, Aras, Omer, Zhao, Huiyong, Qu, Rui, Fagin, James A, Sherman, Eric J, Xu, Bin, Ghossein, Ronald, Chan, Timothy A, Ganly, Ian

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Ligation-Independent Cloning Tobacco Rattle Virus Vector for High-Throughput Virus-Induced Gene Silencing Identifies Roles for NbMADS4-1 and -2 in Floral Development von Dong, Yiyu, Burch-Smith, Tessa M, Liu, Yule, Mamillapalli, Padmavathi, Dinesh-Kumar, Savithramma P

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Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis von Dong, Yiyu, Van Tine, Brian A, Oyama, Toshinao, Wang, Patricia I, Cheng, Emily H, Hsieh, James J

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Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma von Xu, Jianing, Reznik, Ed, Lee, Ho-Joon, Gundem, Gunes, Jonsson, Philip, Sarungbam, Judy, Bialik, Anna, Sanchez-Vega, Francisco, Creighton, Chad J, Hoekstra, Jake, Zhang, Li, Sajjakulnukit, Peter, Kremer, Daniel, Tolstyka, Zachary, Casuscelli, Jozefina, Stirdivant, Steve, Tang, Jie, Schultz, Nikolaus, Jeng, Paul, Dong, Yiyu, Su, Wenjing, Cheng, Emily H, Russo, Paul, Coleman, Jonathan A, Papaemmanuil, Elli, Chen, Ying-Bei, Reuter, Victor E, Sander, Chris, Kennedy, Scott R, Hsieh, James J, Lyssiotis, Costas A, Tickoo, Satish K, Hakimi, A Ari

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Vertical distribution of aerosol optical properties based on aircraft measurements over the Loess Plateau in China von Li, Junxia, Liu, Xingang, Yuan, Liang, Yin, Yan, Li, Zhanqing, Li, Peiren, Ren, Gang, Jin, Lijun, Li, Runjun, Dong, Zipeng, Li, Yiyu, Yang, Junmei

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Characterizing the Immune Microenvironment and Neoantigen Landscape of Hürthle Cell Carcinoma to Identify Potential Immunologic Vulnerabilities von Ganly, Ian, Kuo, Fengshen, Makarov, Vladimir, Dong, Yiyu, Ghossein, Ronald, Xu, Bin, Morris, Luc G T, Chan, Timothy A

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Patient derived xenografts of upper tract urothelial carcinoma: A potential tool for personalized medicine von Kim, Kwanghee, Murray, Katie S, Bagrodia, Aditya, Audenet, Francois, Jebiwott, Sylvia, Gordon, Benjamin, Somma, Alex, LaRosa, Stephen, Dong, Yiyu, Alvim, Ricardo, Hakimi, A. Ari, Hsieh, James, Al-Ahmadie, Hikmat, Rosenberg, Jonathan E., Solit, David B., Coleman, Jonathan

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Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma von Wang, Jianbo, Zhang, Kaihua, Grabowska, Dorota, Li, Aimin, Dong, Yiyu, Day, Ryan, Humphrey, Peter, Lewis, James, Kladney, Raleigh D, Arbeit, Jeffrey M, Weber, Jason D, Chung, Christine H, Michel, Loren S

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Genomic and metabolic characterization of succinate dehydrogenase B deficient renal cell carcinoma von Lee, Chung-Han, Wei, Elizabeth, Lee, William, Chen, Yingbei, Mano, Roy, Hakimi, A. Ari, Dong, Yiyu, Redzematovic, Almedina, Cross, Justin R., Tickoo, Satish, Srinivasan, Ramaprasad, Oschwald, Dayna, Reuter, Victor E., Dunphy, Mark, Cheng, Emily, Motzer, Robert J., Linehan, W. Marston, Hsieh, James

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Abstract C167: Trop2 as a target for breast cancer treatment von Wang, Jianbo, Day, Ryan, Dong, Yiyu, Weintraub, Steven, Michel, Loren

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