Design, synthesis, and biological evaluation of a novel series of 2-(2,6-dioxopiperidin-3-yl)isoquinoline-1,3(2H,4H)-dione derivatives as cereblon modulators von Liu, Yilin, Song, Yuming, Xu, Yingju, Jiang, Meixu, Lu, Haibin

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Combretastatin A-4 eye-using preparation for treating diabetic retinopathy von YINGJU,XU HE

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Development of a Commercial Manufacturing Route to 2‑Fluoroadenine, The Key Unnatural Nucleobase of Islatravir von Hong, Cynthia M, Xu, Yingju, Chung, John Y. L, Schultz, Danielle M, Weisel, Mark, Varsolona, Richard J, Zhong, Yong-Li, Purohit, Akasha K, He, Cyndi Q, Gauthier, Donald R, Humphrey, Guy R, Maloney, Kevin M, Lévesque, François, Wang, Zhixun, Whittaker, Aaron M, Sirota, Eric, McMullen, Jonathan P

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Combining traditional 2D and modern physical organic-derived descriptors to predict enhanced enantioselectivity for the key aza-Michael conjugate addition in the synthesis of Prevy... von Metsänen, Toni T, Lexa, Katrina W, Santiago, Celine B, Chung, Cheol K, Xu, Yingju, Liu, Zhijian, Humphrey, Guy R, Ruck, Rebecca T, Sherer, Edward C, Sigman, Matthew S

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Practical Synthesis of Functionalized 1,5-Disubstituted 1,2,4-Triazole Derivatives von Xu, Yingju, McLaughlin, Mark, Bolton, Emily N, Reamer, Robert A

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Practical Asymmetric Synthesis of a Chiral Piperazinone Derivative von McLaughlin, Mark, Belyk, Kevin, Chen, Cheng-yi, Linghu, Xin, Pan, Jun, Qian, Gang, Reamer, Robert A, Xu, Yingju

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Asymmetric Syntheses of Phosphatidylinositol-3-Phosphates with Saturated and Unsaturated Side Chains through Catalytic Asymmetric Phosphorylation von Sculimbrene, Bianca R, Xu, Yingju, Miller, Scott J

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A General Method for the Synthesis of 3,5-Diarylcyclopentenones via Friedel−Crafts Acylation of Vinyl Chlorides von Xu, Yingju, McLaughlin, Mark, Chen, Cheng-yi, Reamer, Robert A, Dormer, Peter G, Davies, Ian W

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Protein targeting chimeric molecules specific for dual bromodomain 4 (BRD4) and Polo-like kinase 1 (PLK1) proteins in acute myeloid leukemia cells von Mu, Xupeng, Bai, Liting, Xu, Yingju, Wang, Jingyao, Lu, Haibin

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Streamlined Synthesis of Phosphatidylinositol (PI), PI3P, PI3,5P2, and Deoxygenated Analogues as Potential Biological Probes von Xu, Yingju, Sculimbrene, Bianca R, Miller, Scott J

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Unified Total Syntheses of the Inositol Polyphosphates:  d-I-3,5,6P3, d-I-3,4,5P3, d-I-3,4,6P3, and d-I-3,4,5,6P4 via Catalytic Enantioselective and Site-Selective Phosphorylation... von Morgan, Adam J, Komiya, Shio, Xu, Yingju, Miller, Scott J

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Design of an in vitro biocatalytic cascade for the manufacture of islatravir von Huffman, Mark A, Fryszkowska, Anna, Alvizo, Oscar, Borra-Garske, Margie, Campos, Kevin R, Canada, Keith A, Devine, Paul N, Duan, Da, Forstater, Jacob H, Grosser, Shane T, Halsey, Holst M, Hughes, Gregory J, Jo, Junyong, Joyce, Leo A, Kolev, Joshua N, Liang, Jack, Maloney, Kevin M, Mann, Benjamin F, Marshall, Nicholas M, McLaughlin, Mark, Moore, Jeffrey C, Murphy, Grant S, Nawrat, Christopher C, Nazor, Jovana, Novick, Scott, Patel, Niki R, Rodriguez-Granillo, Agustina, Robaire, Sandra A, Sherer, Edward C, Truppo, Matthew D, Whittaker, Aaron M, Verma, Deeptak, Xiao, Li, Xu, Yingju, Yang, Hao

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Preparation of (5α, 13α)-D-azasteroids as key precursors of a new family of potential GABAA receptor modulators von Wang, Cunde, Wang, Shaozhong, Xu, Yingju, Hu, Yuefei, Hu, Hongwen

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A Mild Cu(I)-Catalyzed Oxidative Aromatization of Indolines to Indoles von Peng, Feng, McLaughlin, Mark, Liu, Yizhou, Mangion, Ian, Tschaen, David M, Xu, Yingju

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Asymmetric Hydrogen Bonding Catalysis for the Synthesis of Dihydroquinazoline-Containing Antiviral, Letermovir von Chung, Cheol K, Liu, Zhijian, Lexa, Katrina W, Andreani, Teresa, Xu, Yingju, Ji, Yining, DiRocco, Daniel A, Humphrey, Guy R, Ruck, Rebecca T

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Synthesis of Islatravir Enabled by a Catalytic, Enantioselective Alkynylation of a Ketone von Patel, Niki R., Nawrat, Christopher C., McLaughlin, Mark, Xu, Yingju, Huffman, Mark A., Yang, Hao, Li, Hongming, Whittaker, Aaron M., Andreani, Teresa, Lévesque, François, Fryszkowska, Anna, Brunskill, Andrew, Tschaen, David M., Maloney, Kevin M.

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Development of a Robust Manufacturing Route for Molnupiravir, an Antiviral for the Treatment of COVID-19 von Fier, Patrick S., Xu, Yingju, Poirier, Marc, Brito, Gilmar, Zheng, Michelle, Bade, Rachel, Sirota, Eric, Stone, Kevin, Tan, Lushi, Humphrey, Guy R., Chang, Darryl, Bothe, Jameson, Zhang, Yongqian, Bernardoni, Frank, Castro, Steve, Zompa, Michael A., Taylor, Jerry, Sirk, Kevin M., Diaz-Santana, Anthony, Diribe, Ike, Emerson, Khateeta M., Krishnamurthi, Bharath, Zhao, Ralph, Ward, Michael, Xiao, Chengqian, Ouyand, Honggui, Zhan, Jianfeng, Morris, William J.

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Invention of MK-8262, a Cholesteryl Ester Transfer Protein (CETP) Inhibitor Backup to Anacetrapib with Best-in-Class Properties von Vachal, Petr, Duffy, Joseph L, Campeau, Louis-Charles, Amin, Rupesh P, Mitra, Kaushik, Murphy, Beth Ann, Shao, Pengcheng P, Sinclair, Peter J, Ye, Feng, Katipally, Revathi, Lu, Zhijian, Ondeyka, Debra, Chen, Yi-Heng, Zhao, Kake, Sun, Wanying, Tyagarajan, Sriram, Bao, Jianming, Wang, Sheng-Ping, Cote, Josee, Lipardi, Concetta, Metzger, Daniel, Leung, Dennis, Hartmann, Georgy, Wollenberg, Gordon K, Liu, Jian, Tan, Lushi, Xu, Yingju, Chen, Qinghao, Liu, Guiquan, Blaustein, Robert O, Johns, Douglas G

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Polymorphs, Particle Size, and a Pandemic: Development of a Scalable Crystallization Process for Molnupiravir, an Antiviral for the Treatment of COVID-19 von Bade, Rachel, Bothe, Jameson R., Sirota, Eric, Brunskill, Andrew P. J., Newman, Justin A., Zhang, Yongqian, Tan, Melissa, Zheng, Michelle, Brito, Gilmar, Poirier, Marc, Fier, Patrick S., Xu, Yingju, Ward, Michael D., Stone, Kevin, Lee, Ivan H., Gmitter, Andrew J., Bernardoni, Frank, Zompa, Michael A., Luo, Hanlin, Patel, Sanjaykumar, Masiuk, Tina, Mora, Jeff, Ni, Tong, Okoh, Grace A., Tarabokija, James, Liu, Jiaying, Lowinger, Michael B., Mahmood, Tariq

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Etoposide Amorphous Nanopowder for Improved Oral Bioavailability: Formulation Development, Optimization, in vitro and in vivo Evaluation von Wang, Yue, Wang, Shuhang, Xu, Yingju, Wang, Ping, Li, Sukai, Liu, Lu, Liu, Mengyan, Jin, Xiangqun

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