Cathepsin B promotes collagen biosynthesis, which drives bronchiolitis obliterans syndrome von Morrone, Carmela, Smirnova, Natalia F., Jeridi, Aicha, Kneidinger, Nikolaus, Hollauer, Christine, Schupp, Jonas Christian, Kaminski, Naftali, Jenne, Dieter, Eickelberg, Oliver, Yildirim, Ali Onder

Volltext

A drug screen with approved compounds identifies amlexanox as a novel Wnt/β‐catenin activator inducing lung epithelial organoid formation von Costa, Rita, Wagner, Darcy E., Doryab, Ali, De Santis, Martina M., Schorpp, Kenji, Rothenaigner, Ina, Lehmann, Mareike, Baarsma, Hoeke A., Liu, Xueping, Schmid, Otmar, Campillos, Monica, Yildirim, Ali Önder, Hadian, Kamyar, Königshoff, Melanie

Volltext

Free DNA in Cystic Fibrosis Airway Fluids Correlates with Airflow Obstruction von Marcos, Veronica, Zhou-Suckow, Zhe, Önder Yildirim, Ali, Bohla, Alexander, Hector, Andreas, Vitkov, Ljubomir, Krautgartner, Wolf Dietrich, Stoiber, Walter, Griese, Matthias, Eickelberg, Oliver, Mall, Marcus A, Hartl, Dominik

Volltext

The effect of multiple outgrowths from bronchial tissue explants on progenitor/stem cell number in primary bronchial epithelial cell cultures from smokers and patients with COPD von Bostancieri, Nuray, Bakir, Kemal, Kul, Seval, Eralp, Ayhan, Kayalar, Ozgecan, Konyalilar, Nur, Rajabi, Hadi, Yuncu, Mehmet, Yildirim, Ali Önder, Bayram, Hasan

Volltext

Innate Immunity of the Lung: From Basic Mechanisms to Translational Medicine von Hartl, Dominik, Tirouvanziam, Rabindra, Laval, Julie, Greene, Catherine M., Habiel, David, Sharma, Lokesh, Yildirim, Ali Önder, Dela Cruz, Charles S., Hogaboam, Cory M.

Volltext

Cigarette smoke-induced iBALT mediates macrophage activation in a B cell-dependent manner in COPD von John-Schuster, Gerrit, Hager, Katrin, Conlon, Thomas M, Irmler, Martin, Beckers, Johannes, Eickelberg, Oliver, Yildirim, Ali Önder

Volltext

LungVis 1.0: an automatic AI-powered 3D imaging ecosystem unveils spatial profiling of nanoparticle delivery and acinar migration of lung macrophages von Yang, Lin, Liu, Qiongliang, Kumar, Pramod, Sengupta, Arunima, Farnoud, Ali, Shen, Ruolin, Trofimova, Darya, Ziegler, Sebastian, Davoudi, Neda, Doryab, Ali, Yildirim, Ali Önder, Diefenbacher, Markus E., Schiller, Herbert B., Razansky, Daniel, Piraud, Marie, Burgstaller, Gerald, Kreyling, Wolfgang G., Isensee, Fabian, Rehberg, Markus, Stoeger, Tobias, Schmid, Otmar

Volltext

TRPA1 channels: expression in non-neuronal murine lung tissues and dispensability for hyperoxia-induced alveolar epithelial hyperplasia von Kannler, Martina, Lüling, Robin, Yildirim, Ali Önder, Gudermann, Thomas, Steinritz, Dirk, Dietrich, Alexander

Volltext

Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis von Hofmann, Katharina, Fiedler, Susanne, Vierkotten, Sarah, Weber, Jonas, Klee, Stephan, Jia, Jie, Zwickenpflug, Wolfgang, Flockerzi, Veit, Storch, Ursula, Yildirim, Ali Önder, Gudermann, Thomas, Königshoff, Melanie, Dietrich, Alexander

Volltext

Breathing-induced stretch enhances the efficacy of an inhaled and orally delivered anti-fibrosis drug in vitro von Doryab, Ali, Heydarian, Motaharehsadat, Yildirim, Ali Önder, Hilgendorff, Anne, Behr, Jürgen, Schmid, Otmar

Volltext

Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source von Gradl, Regine, Dierolf, Martin, Hehn, Lorenz, Günther, Benedikt, Yildirim, Ali Önder, Gleich, Bernhard, Achterhold, Klaus, Pfeiffer, Franz, Morgan, Kaye Susannah

Volltext

Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease von Kapellos, Theodore S., Baßler, Kevin, Fujii, Wataru, Nalkurthi, Christina, Schaar, Anna C., Bonaguro, Lorenzo, Pecht, Tal, Galvao, Izabela, Agrawal, Shobhit, Saglam, Adem, Dudkin, Erica, Frishberg, Amit, de Domenico, Elena, Horne, Arik, Donovan, Chantal, Kim, Richard Y., Gallego-Ortega, David, Gillett, Tessa E., Ansari, Meshal, Schulte-Schrepping, Jonas, Offermann, Nina, Antignano, Ignazio, Sivri, Burcu, Lu, Wenying, Eapen, Mathew S., van Uelft, Martina, Osei-Sarpong, Collins, van den Berge, Maarten, Donker, Hylke C., Groen, Harry J.M., Sohal, Sukhwinder S., Klein, Johanna, Schreiber, Tina, Feißt, Andreas, Yildirim, Ali Önder, Schiller, Herbert B., Nawijn, Martijn C., Becker, Matthias, Händler, Kristian, Beyer, Marc, Capasso, Melania, Ulas, Thomas, Hasenauer, Jan, Pizarro, Carmen, Theis, Fabian J., Hansbro, Philip M., Skowasch, Dirk, Schultze, Joachim L.

Volltext

Systems toxicology of complex wood combustion aerosol reveals gaseous carbonyl compounds as critical constituents von Dilger, Marco, Armant, Olivier, Ramme, Larissa, Mülhopt, Sonja, Sapcariu, Sean C., Schlager, Christoph, Dilger, Elena, Reda, Ahmed, Orasche, Jürgen, Schnelle-Kreis, Jürgen, Conlon, Thomas M., Yildirim, Ali Önder, Hartwig, Andrea, Zimmermann, Ralf, Hiller, Karsten, Diabaté, Silvia, Paur, Hanns-Rudolf, Weiss, Carsten

Volltext

A novel anti-inflammatory and pro-resolving role for resolvin D1 in acute cigarette smoke-induced lung inflammation von Hsiao, Hsi-Min, Sapinoro, Ramil E, Thatcher, Thomas H, Croasdell, Amanda, Levy, Elizabeth P, Fulton, Robert A, Olsen, Keith C, Pollock, Stephen J, Serhan, Charles N, Phipps, Richard P, Sime, Patricia J

Volltext

Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation von Rehm, Salome R. T., Smirnova, Natalia F., Morrone, Carmela, Götzfried, Jessica, Feuchtinger, Annette, Pedersen, John, Korkmaz, Brice, Yildirim, Ali Önder, Jenne, Dieter E.

Volltext

The dynamic shuttling of SIRT1 between cytoplasm and nuclei in bronchial epithelial cells by single and repeated cigarette smoke exposure von Yanagisawa, Satoru, Baker, Jonathan R, Vuppusetty, Chaitanya, Koga, Takeshi, Colley, Thomas, Fenwick, Peter, Donnelly, Louise E, Barnes, Peter J, Ito, Kazuhiro

Volltext

Fumarate hydratase: a new checkpoint of metabolic regulation in inflammatory macrophages von Jeridi, Aicha, Kapellos, Theodore S., Yildirim, Ali Önder

Volltext

Systematic phenotyping and correlation of biomarkers with lung function and histology in lung fibrosis von Fernandez, Isis E, Amarie, Oana V, Mutze, Kathrin, Königshoff, Melanie, Yildirim, Ali Önder, Eickelberg, Oliver

Volltext

Cigarette smoke causes acute airway disease and exacerbates chronic obstructive lung disease in neonatal mice von Jia, Jie, Conlon, Thomas M, Ballester Lopez, Carolina, Seimetz, Michael, Bednorz, Mariola, Zhou-Suckow, Zhe, Weissmann, Norbert, Eickelberg, Oliver, Mall, Marcus A, Yildirim, Ali Önder

Volltext

Cholesterol metabolism promotes B‐cell positioning during immune pathogenesis of chronic obstructive pulmonary disease von Jia, Jie, Conlon, Thomas M, Sarker, Rim SJ, Taşdemir, Demet, Smirnova, Natalia F, Srivastava, Barkha, Verleden, Stijn E, Güneş, Gizem, Wu, Xiao, Prehn, Cornelia, Gao, Jiaqi, Heinzelmann, Katharina, Lintelmann, Jutta, Irmler, Martin, Pfeiffer, Stefan, Schloter, Michael, Zimmermann, Ralf, Hrabé de Angelis, Martin, Beckers, Johannes, Adamski, Jerzy, Bayram, Hasan, Eickelberg, Oliver, Yildirim, Ali Önder

Volltext