Spiroindolones, a Potent Compound Class for the Treatment of Malaria von Rottmann, Matthias, McNamara, Case, Yeung, Bryan K.S, Lee, Marcus C.S, Zou, Bin, Russell, Bruce, Seitz, Patrick, Plouffe, David M, Dharia, Neekesh V, Tan, Jocelyn, Cohen, Steven B, Spencer, Kathryn R, González-Páez, Gonzalo E, Lakshminarayana, Suresh B, Goh, Anne, Suwanarusk, Rossarin, Jegla, Timothy, Schmitt, Esther K, Beck, Hans-Peter, Brun, Reto, Nosten, Francois, Renia, Laurent, Dartois, Veronique, Keller, Thomas H, Fidock, David A, Winzeler, Elizabeth A, Diagana, Thierry T

Volltext

Prediction of mechanical properties of knitted fabrics under tensile and shear loading: Mesoscale analysis using representative unit cells and its validation von Dinh, T.D., Weeger, O., Kaijima, S., Yeung, S.-K.

Volltext

Digital design and nonlinear simulation for additive manufacturing of soft lattice structures von Weeger, O., Boddeti, N., Yeung, S.-K., Kaijima, S., Dunn, M.L.

Volltext

The Spiroindolone Drug Candidate NITD609 Potently Inhibits Gametocytogenesis and Blocks Plasmodium falciparum Transmission to Anopheles Mosquito Vector von PELT-KOOPS, J. C. Van, PETT, H. E, GRAUMANS, W, DER VEGTE-BOLMER, M. Van, GEMERT, G. J. Van, ROTTMANN, M, YEUNG, B. K. S, DIAGANA, T. T, SAUERWEIN, R. W

Volltext

PI4 Kinase Is a Prophylactic but Not Radical Curative Target in Plasmodium vivax-Type Malaria Parasites von Zeeman, Anne-Marie, Lakshminarayana, Suresh B, van der Werff, Nicole, Klooster, Els J, Voorberg-van der Wel, Annemarie, Kondreddi, Ravinder R, Bodenreider, Christophe, Simon, Oliver, Sauerwein, Robert, Yeung, Bryan K S, Diagana, Thierry T, Kocken, Clemens H M

Volltext

KAI407, a Potent Non-8-Aminoquinoline Compound That Kills Plasmodium cynomolgi Early Dormant Liver Stage Parasites In Vitro von ZEEMAN, Anne-Marie, VAN AMSTERDAM, Sandra M, SAUERWEIN, Robert, GAGARING, Kerstin, BORBOA, Rachel, ZHONG CHEN, KUHEN, Kelli, GLYNNE, Richard J, CHATTERJEE, Arnab K, NAGLE, Advait, ROLAND, Jason, WINZELER, Elizabeth A, MCNAMARA, Case W, LEROY, Didier, CAMPO, Brice, DIAGANA, Thierry T, YEUNG, Bryan K. S, THOMAS, Alan W, KOCKEN, Clemens H. M, VOORBERG-VAN DER WEL, Annemarie, KLOOSTER, Els J, VAN DEN BERG, Alexander, REMARQUE, Edmond J, PLOUFFE, David M, VAN GEMERT, Geert-Jan, LUTY, Adrian

Volltext

Identifying the genetic causes for prenatally diagnosed structural congenital anomalies (SCAs) by whole-exome sequencing (WES) von Leung, Gordon K C, Mak, Christopher C Y, Fung, Jasmine L F, Wong, Wilfred H S, Tsang, Mandy H Y, Yu, Mullin H C, Pei, Steven L C, Yeung, K S, Mok, Gary T K, Lee, C P, Hui, Amelia P W, Tang, Mary H Y, Chan, Kelvin Y K, Liu, Anthony P Y, Yang, Wanling, Sham, P C, Kan, Anita S Y, Chung, Brian H Y

Volltext

Pharmacokinetic-pharmacodynamic analysis of spiroindolone analogs and KAE609 in a murine malaria model von Lakshminarayana, Suresh B, Freymond, Céline, Fischli, Christoph, Yu, Jing, Weber, Sebastian, Goh, Anne, Yeung, Bryan K S, Ho, Paul C, Dartois, Véronique, Diagana, Thierry T, Rottmann, Matthias, Blasco, Francesca

Volltext

Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria von Yeung, Bryan K. S, Zou, Bin, Rottmann, Matthias, Lakshminarayana, Suresh B, Ang, Shi Hua, Leong, Seh Yong, Tan, Jocelyn, Wong, Josephine, Keller-Maerki, Sonja, Fischli, Christoph, Goh, Anne, Schmitt, Esther K, Krastel, Philipp, Francotte, Eric, Kuhen, Kelli, Plouffe, David, Henson, Kerstin, Wagner, Trixie, Winzeler, Elizabeth A, Petersen, Frank, Brun, Reto, Dartois, Veronique, Diagana, Thierry T, Keller, Thomas H

Volltext

Robust continuous in vitro culture of the Plasmodium cynomolgi erythrocytic stages von Chua, Adeline C. Y., Ong, Jessica Jie Ying, Malleret, Benoit, Suwanarusk, Rossarin, Kosaisavee, Varakorn, Zeeman, Anne-Marie, Cooper, Caitlin A., Tan, Kevin S. W., Zhang, Rou, Tan, Bee Huat, Abas, Siti Nurdiana, Yip, Andy, Elliot, Anne, Joyner, Chester J., Cho, Jee Sun, Breyer, Kate, Baran, Szczepan, Lange, Amber, Maher, Steven P., Nosten, François, Bodenreider, Christophe, Yeung, Bryan K. S., Mazier, Dominique, Galinski, Mary R., Dereuddre-Bosquet, Nathalie, Le Grand, Roger, Kocken, Clemens H. M., Rénia, Laurent, Kyle, Dennis E., Diagana, Thierry T., Snounou, Georges, Russell, Bruce, Bifani, Pablo

Volltext

Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design von Harbut, Michael B., Patel, Bhumit A., Yeung, Bryan K. S., McNamara, Case W., Bright, A. Taylor, Ballard, Jaime, Supek, Frantisek, Golde, Todd E., Winzeler, Elizabeth A., Diagana, Thierry T., Greenbaum, Doron C.

Volltext

Design and Complexity Optimization of a New Digital IF for Software Radio Receivers With Prescribed Output Accuracy von Chan, S.C., Tsui, K.M., Yeung, K.S., Yuk, T.I.

Volltext

The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites von Dembele, L., Ang, X., Chavchich, M., Bonamy, G. M. C., Selva, J. J., Lim, M. Yi-Xiu, Bodenreider, C., Yeung, B. K. S., Nosten, F., Russell, B. M., Edstein, M. D., Straimer, J., Fidock, D. A., Diagana, T. T., Bifani, P.

Volltext

Changes in rates and severity of compensation claims for asthma due to diisocyanates: a possible effect of medical surveillance measures von Tarlo, S M, Liss, G M, Yeung, K S

Volltext

The design and multiplier-less realization of software radio receivers with reduced system delay von Yeung, K.S., Chan, S.C.

Volltext

Moderate‐ to long‐term therapeutic outcomes of treated aggressive periodontitis patients without regular supportive care von Goh, V., Nihalani, D., Yeung, K. W. S., Corbet, E. F., Leung, W. K.

Volltext

Mechanistic study of the spiroindolones: a new class of antimalarials von Zou, Bin, Yap, Peiling, Sonntag, Louis-Sebastian, Leong, Seh Yong, Yeung, Bryan K S, Keller, Thomas H

Volltext

Interspecies variation in Candida biofilm formation studied using the Calgary biofilm device von PARAHITIYAWA, N. B., SAMARANAYAKE, Y. H., SAMARANAYAKE, L. P., YE, J., TSANG, P. W. K., CHEUNG, B. P. K., YAU, J. Y. Y., YEUNG, S. K. W.

Volltext

Silver-Russell syndrome in Hong Kong von Luk, H M, Yeung, K S, Wong, W L, Chung, B Hy, Tong, T Mf, Lo, I Fm

Volltext

Natural product drug discovery: the successful optimization of ISP-1 and halichondrin B von Yeung, Bryan KS

Volltext