A general approach to calculating isotopic distributions for mass spectrometry von Yergey, James A.

Volltext

Improving metabolic stability of phosphodiesterase-4 inhibitors containing a substituted catechol: prevention of reactive intermediate formation and covalent binding von Chauret, Nathalie, Guay, Daniel, Li, Chun, Day, Stephen, Silva, José, Blouin, Marc, Ducharme, Yves, Yergey, James A., Nicoll-Griffith, Deborah A.

Volltext

Dioxabicyclooctanyl Naphthalenenitriles as Nonredox 5-Lipoxygenase Inhibitors:  Structure−Activity Relationship Study Directed toward the Improvement of Metabolic Stability von Delorme, Daniel, Ducharme, Yves, Brideau, Christine, Chan, Chi-Chung, Chauret, Nathalie, Desmarais, Sylvie, Dubé, Daniel, Falgueyret, Jean-Pierre, Fortin, Réjean, Guay, Jocelyne, Hamel, Pierre, Jones, Tom R, Lépine, Carole, Li, Chun, McAuliffe, Malia, McFarlane, Cyril S, Nicoll-Griffith, Deborah A, Riendeau, Denis, Yergey, James A, Girard, Yves

Volltext

Diversity in the Oxidation of Substrates by Cytochrome P450 2D6:  Lack of an Obligatory Role of Aspartate 301−Substrate Electrostatic Bonding von Guengerich, F. Peter, Miller, Grover P, Hanna, Imad H, Martin, Martha V, Léger, Serge, Black, Cameron, Chauret, Nathalie, Silva, José M, Trimble, Laird A, Yergey, James A, Nicoll-Griffith, Deborah A

Volltext

Description of a 96-Well Plate Assay to Measure Cytochrome P4503A Inhibition in Human Liver Microsomes Using a Selective Fluorescent Probe von Chauret, Nathalie, Tremblay, Nathalie, Lackman, Rebecca L., Gauthier, Jacques-Yves, Silva, José M., Marois, Jean, Yergey, James A., Nicoll-Griffith, Deborah A.

Volltext

Quinolinic acid in cerebrospinal fluid and serum in HIV-1 Infection: Relationship to clinical and neurological status von Heyes, Melvyn P., Brew, Bruce J., Martin, Alex, Price, Richard W., Salazar, Andres M., Sidtis, John J., Yergey, James A., Mouradian, M. Maral, Sadler, Abigail E., Keilp, John, Rubinow, David, Markey, Sanford P.

Volltext

In vitro metabolism considerations, including activity testing of metabolites, in the discovery and selection of the COX-2 inhibitor etoricoxib (MK-0663) von Chauret, Nathalie, Yergey, James A, Brideau, Christine, Friesen, Richard W, Mancini, Joseph, Riendeau, Denis, Silva, José, Styhler, Angela, Trimble, Laird A, Nicoll-Griffith, Deborah A

Volltext

Synthesis, characterization, and activity of metabolites derived from the cyclooxygenase-2 inhibitor rofecoxib (MK-0966, Vioxx ™) von Nicoll-Griffith, Deborah A, Yergey, James A, Trimble, Laird A, Silva, José M, Li, Chun, Chauret, Nathalie, Gauthier, Jacques Yves, Grimm, Erich, Léger, Serge, Roy, Patrick, Thérien, Michel, Wang, Zhaoyin, Prasit, Peppi, Zamboni, Robert, Young, Robert N, Brideau, Christine, Chan, Chi-Chung, Mancini, Joseph, Riendeau, Denis

Volltext

Discovery of a potent and selective COX-2 inhibitor in the alkoxy lactone series with optimized metabolic profile von Leblanc, Yves, Roy, Patrick, Wang, Zhaoyin, Li, Chun Sing, Chauret, Nathalie, Nicoll-Griffith, Deborah A., Silva, José M., Aubin, Yves, Yergey, James A., Chan, Chi Chung, Riendeau, Denis, Brideau, Christine, Gordon, Robert, Xu, Lijing, Webb, Janine, Visco, Denise M., Prasit, Petpiboon

Volltext

Chemical characterization of organic adsorbates on diesel particulate matter von Yergey, James A, Risby, Terence H, Lestz, Samuel S

Volltext

A general approach to calculating isotopic distributions for mass spectrometry von Yergey, James A.

Volltext

Characterization of the in vitro oxidative metabolites of the COX-2 selective inhibitor L-766,112 von Trimble, Laird A, Chauret, Nathalie, Silva, JoséM, Nicoll-Griffith, Deborah A, Li, Chun-Sing, Yergey, James A

Volltext

Integrated Application of Capillary HPLC/Continuous-Flow Liquid Secondary Ion Mass Spectrometry to Discovery Stage Metabolism Studies von Li, Chun, Chauret, Nathalie, Ducharme, Yves, Trimble, Laird A, Nicoll-Griffith, Deborah A, Yergey, James A

Volltext

High-performance liquid chromatography/thermospray mass spectrometry of eicosanoids and novel oxygenated metabolites of docosahexaenoic acid von Yergey, James A, Kim, Hee Yong, Salem, Norman

Volltext

Purification and Characterization of Recombinant Human Cyclooxygenase-2 von Percival, M.D., Ouellet, M., Vincent, C.J., Yergey, J.A., Kennedy, B.P., Oneill, G.P.

Volltext

Continuous Flow Liquid Secondary Ion Mass Spectrometric Characterization of Phospholipid Molecular Species von Li, Chun, Yergey, James A.

Volltext

Mass spectrometric analysis of arachidonyl-containing phospholipids in human U937 cells von Li, Chun, McClory, Andrew, Wong, Elizabeth, Yergey, James A.

Volltext

Enhancement of mass spectrometric detection of LTC 4, LTD 4, and LTE 4 by derivatization von Mamer, Orval A., Just, George, Li, Chun-Sing, Préville, Patrice, Watson, Sara, Young, Robert, Yergey, James A.

Volltext

Resolution requirements for middle molecule mass spectrometry von Yergey, James A., Cotter, Robert J., Heller, David, Fenselau, Catherine

Volltext

Prostaglandins in Human Cerebrospinal Fluid? von YERGEY, JAMES A., SALEM JR, NORMAN, KARANIAN, JOHN W., LINNOILA, MARKKU, HEYES, MELVYN P.

Volltext