Oxidative Cyclizations in a Nonpolar Solvent Using Molecular Oxygen and Studies on the Stereochemistry of Oxypalladation von Trend, Raissa M, Ramtohul, Yeeman K, Stoltz, Brian M

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Pd-Catalyzed Enantioselective Aerobic Oxidation of Secondary Alcohols: Applications to the Total Synthesis of Alkaloids von Krishnan, Shyam, Bagdanoff, Jeffrey T, Ebner, David C, Ramtohul, Yeeman K, Tambar, Uttam K, Stoltz, Brian M

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Direct C-Arylation of β-Enamino Esters and Ketones with Arynes von Ramtohul, Yeeman K, Chartrand, Anik

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Development of a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor (MK-8245) to Establish a Therapeutic Window for the Treatment of Diabetes and Dyslipidemia von Oballa, Renata M, Belair, Liette, Black, W. Cameron, Bleasby, Kelly, Chan, Chi Chung, Desroches, Carole, Du, Xiaobing, Gordon, Robert, Guay, Jocelyne, Guiral, Sebastien, Hafey, Michael J, Hamelin, Emelie, Huang, Zheng, Kennedy, Brian, Lachance, Nicolas, Landry, France, Li, Chun Sing, Mancini, Joseph, Normandin, Denis, Pocai, Alessandro, Powell, David A, Ramtohul, Yeeman K, Skorey, Kathryn, Sørensen, Dan, Sturkenboom, Wayne, Styhler, Angela, Waddleton, Deena M, Wang, Hao, Wong, Simon, Xu, Lijing, Zhang, Lei

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Palladium-Catalyzed Oxidative Wacker Cyclizations in Nonpolar Organic Solvents with Molecular Oxygen: A Stepping Stone to Asymmetric Aerobic Cyclizations von Trend, Raissa M., Ramtohul, Yeeman K., Ferreira, Eric M., Stoltz, Brian M.

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Thiazole analog as stearoyl-CoA desaturase 1 inhibitor von Li, Chun Sing, Belair, Liette, Guay, Jocelyne, Murgasva, Renata, Sturkenboom, Wayne, Ramtohul, Yeeman K., Zhang, Lei, Huang, Zheng

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Discovery of potent and liver-targeted stearoyl-CoA desaturase (SCD) inhibitors in a bispyrrolidine series von Lachance, Nicolas, Gareau, Yves, Guiral, Sébastien, Huang, Zheng, Isabel, Elise, Leclerc, Jean-Philippe, Léger, Serge, Martins, Evelyn, Nadeau, Christian, Oballa, Renata M., Ouellet, Stéphane G., Powell, David A., Ramtohul, Yeeman K., Tranmer, Geoffrey K., Trinh, Thao, Wang, Hao, Zhang, Lei

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SAR and optimization of thiazole analogs as potent stearoyl-CoA desaturase inhibitors von Ramtohul, Yeeman K., Black, Cameron, Chan, Chi-Chung, Crane, Sheldon, Guay, Jocelyne, Guiral, Sébastien, Huang, Zheng, Oballa, Renata, Xu, Li-Jing, Zhang, Lei, Li, Chun Sing

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Bicyclic heteroaryl inhibitors of stearoyl-CoA desaturase: From systemic to liver-targeting inhibitors von Ramtohul, Yeeman K., Powell, David, Leclerc, Jean-Philippe, Leger, Serge, Oballa, Renata, Black, Cameron, Isabel, Elise, Li, Chun Sing, Crane, Sheldon, Robichaud, Joel, Guay, Jocelyne, Guiral, Sébastien, Zhang, Lei, Huang, Zheng

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Discovery of potent and liver-selective stearoyl-CoA desaturase (SCD) inhibitors in an acyclic linker series von Lachance, Nicolas, Guiral, Sébastien, Huang, Zheng, Leclerc, Jean-Philippe, Li, Chun Sing, Oballa, Renata M., Ramtohul, Yeeman K., Wang, Hao, Wu, Jin, Zhang, Lei

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Conversion of systemically-distributed triazole-based stearoyl-CoA desaturase (SCD) uHTS hits into liver-targeted SCD inhibitors von Leclerc, Jean-Philippe, Falgueyret, Jean-Pierre, Girardin, Mélina, Guay, Jocelyne, Guiral, Sébastien, Huang, Zheng, Li, Chun Sing, Oballa, Renata, Ramtohul, Yeeman K., Skorey, Kathryn, Tawa, Paul, Wang, Hao, Zhang, Lei

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Serine and Threonine β-Lactones:  A New Class of Hepatitis A Virus 3C Cysteine Proteinase Inhibitors von Lall, Manjinder S, Ramtohul, Yeeman K, James, Michael N. G, Vederas, John C

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Synthesis and Evaluation of Keto-Glutamine Analogues as Inhibitors of Hepatitis A Virus 3C Proteinase von Ramtohul, Yeeman K, James, Michael N. G, Vederas, John C

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Pseudoxazolones, a new class of inhibitors for cysteine proteinases: inhibition of hepatitis A virus and human rhinovirus 3C proteinases von Ramtohul, Yeeman K., Martin, Nathaniel I., Silkin, Lara, James, Michael N. G., Vederas, John C.

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2-Aryl benzimidazoles: Human SCD1-specific stearoyl coenzyme-A desaturase inhibitors von Powell, David A., Ramtohul, Yeeman, Lebrun, Marie-Eve, Oballa, Renata, Bhat, Sathesh, Falgueyret, Jean-Pierre, Guiral, Sebastien, Huang, Zheng, Skorey, Kathryn, Tawa, Paul, Zhang, Lei

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A Multiplexed Cell Assay in HepG2 Cells for the Identification of Delta-5, Delta-6, and Delta-9 Desaturase and Elongase Inhibitors von Zhang, Lei, Ramtohul, Yeeman, Gagné, Sebastien, Styhler, Angela, Wang, Hao, Guay, Jocelyne, Huang, Zheng

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Design and synthesis of potent, isoxazole-containing renin inhibitors von Fournier, Pierre-André, Arbour, Mélissa, Cauchon, Elizabeth, Chen, Austin, Chefson, Amandine, Ducharme, Yves, Falgueyret, Jean-Pierre, Gagné, Sébastien, Grimm, Erich, Han, Yongxin, Houle, Robert, Lacombe, Patrick, Lévesque, Jean-François, MacDonald, Dwight, Mackay, Bruce, McKay, Dan, Percival, M. David, Ramtohul, Yeeman, St-Jacques, René, Toulmond, Sylvie

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3,4-Diarylpiperidines as potent renin inhibitors von Lacombe, Patrick, Arbour, Mélissa, Aspiotis, Renée, Cauchon, Elizabeth, Chen, Austin, Dubé, Daniel, Falgueyret, Jean-Pierre, Fournier, Pierre-André, Gallant, Michel, Grimm, Erich, Han, Yongxin, Juteau, Hélène, Liu, Suzanna, Mellon, Christophe, Ramtohul, Yeeman, Simard, Daniel, St-Jacques, René, Tsui, Gavin Chit

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Synthesis of pseudoxazolones and their inhibition of the 3C cysteine proteinases from hepatitis A virus and human rhinovirus-14 von Ramtohul, Yeeman K., Martin, Nathaniel I., Silkin, Lara, James, Michael N. G., Vederas, John C.

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Mannose derivatives for treating bacterial infections von Gallant, Michel, Ramtohul, Yeeman K, Vallee, Frederic, Dietrich, Evelyne, Vaillancourt, Louis, Cadilhac, Caroline, Liu, Bingcan, Poisson, Carl, Das, Sanjoy Kumar, Reddy, Thumkunta Jagadeeswar, Martel, Julien

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