Proteasome Inhibition Causes Regression of Leukemia and Abrogates BCR-ABL―Induced Evasion of Apoptosis in Part through Regulation of Forkhead Tumor Suppressors von JAGANI, Zainab, KELI SONG, YECKES RODIN, Heather, MILLER, Kenneth, KHOSRAVI-FAR, Roya, KUTOK, Jeffery L, RAJAN DEWAR, M, MELET, Armelle, SANTOS, Tanya, GRASSIAN, Alexandra, GHAFFARI, Saghi, WU, Catherine, RUIBAO REN

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797 Significant anti-tumor activity of HBI-8000, a class I histone deacetylase inhibitor (HDACi) in combination with nivolumab (NIVO) in anti-PD1 therapy-naïve advanced melanoma (T... von Khushalani, Nikhil, Brohl, Andrew, Markowitz, Joseph, Bazhenova, Lyudmila, Daniels, Gregory, Yeckes-Rodin, Heather, Fu, Siqing, McCormick, Lori, Kurman, Michael, Gillings, Mireille, Lee, Gloria, Eroglu, Zeynep

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Bortezomib treatment causes remission in a Ph+ALL patient and reveals FoxO as a theranostic marker von Dewar, Rajan, Chen, Sing-Tsung, Yeckes-Rodin, Heather, Miller, Kenneth, Khosravi-Far, Roya

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Phase 1/1b open-label, dose-escalation study of fruquintinib in patients with advanced solid tumors in the United States von Wang-Gillam, Andrea, Schelman, William, Ukrainskyj, Stacey, Chien, Caly, Gonzalez, Martha, Yang, Zhao, Kania, Marek, Yeckes-Rodin, Heather

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Phase 1/1b trial of fruquintinib in patients with advanced solid tumors: Preliminary results of the dose expansion cohorts in refractory metastatic colorectal cancer von Dasari, Arvind, Hubbard, Joleen M., Eng, Cathy, Yeckes-Rodin, Heather, Ukrainskyj, Stacey M, Yang, Zhao, Schelman, William R., Kania, Marek K., Bekaii-Saab, Tanios S.

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Eganelisib, a First-in-Class PI3Kγ Inhibitor, in Patients with Advanced Solid Tumors: Results of the Phase 1/1b MARIO-1 Trial von Hong, David S, Postow, Michael, Chmielowski, Bartosz, Sullivan, Ryan, Patnaik, Amita, Cohen, Ezra E W, Shapiro, Geoffrey, Steuer, Conor, Gutierrez, Martin, Yeckes-Rodin, Heather, Ilaria, Robert, O'Connell, Brenda, Peng, Joanna, Peng, Guangbin, Zizlsperger, Nora, Tolcher, Anthony, Wolchok, Jedd D

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352 Updated clinical data from the squamous cell carcinoma of the head and neck (SCCHN) expansion cohort of an ongoing Ph1/1b Study of eganelisib (formerly IPI-549) in combination... von Cohen, Ezra, Postow, Michael, Sullivan, Ryan, Hong, David, Yeckes-Rodin, Heather, McCarter, Jerry, Zizlsperger, Nora, Kutok, Jeffery, Brenda O’Connell, Page, Kara, Roberts, Jennifer, Zhang, Halle, Chmielowski, Bartosz

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Out Foxing Bcr-Abl von Claxton, David F.

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Cyclin-dependent kinase 2 (CDK2) inhibitors and others novel CDK inhibitors (CDKi) in breast cancer: clinical trials, current impact, and future directions von Gerosa, Riccardo, De Sanctis, Rita, Jacobs, Flavia, Benvenuti, Chiara, Gaudio, Mariangela, Saltalamacchia, Giuseppe, Torrisi, Rosalba, Masci, Giovanna, Miggiano, Chiara, Agustoni, Francesco, Pedrazzoli, Paolo, Santoro, Armando, Zambelli, Alberto

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