Human chimeric antigen receptor macrophages for cancer immunotherapy von Klichinsky, Michael, Ruella, Marco, Shestova, Olga, Lu, Xueqing Maggie, Best, Andrew, Zeeman, Martha, Schmierer, Maggie, Gabrusiewicz, Konrad, Anderson, Nicholas R., Petty, Nicholas E., Cummins, Katherine D., Shen, Feng, Shan, Xinhe, Veliz, Kimberly, Blouch, Kristin, Yashiro-Ohtani, Yumi, Kenderian, Saad S., Kim, Miriam Y., O’Connor, Roddy S., Wallace, Stephen R., Kozlowski, Miroslaw S., Marchione, Dylan M., Shestov, Maksim, Garcia, Benjamin A., June, Carl H., Gill, Saar

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NOTCH1 and NOTCH3 Coordinate Esophageal Squamous Differentiation Through a CSL-Dependent Transcriptional Network von Ohashi, Shinya, Natsuizaka, Mitsuteru, Yashiro–Ohtani, Yumi, Kalman, Ross A, Nakagawa, Momo, Wu, Lizi, Klein–Szanto, Andres J, Herlyn, Meenhard, Diehl, J. Alan, Katz, Jonathan P, Pear, Warren S, Seykora, John T, Nakagawa, Hiroshi

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The expression of Sox17 identifies and regulates haemogenic endothelium von Clarke, Raedun L., Yzaguirre, Amanda D., Yashiro-Ohtani, Yumi, Bondue, Antoine, Blanpain, Cedric, Pear, Warren S., Speck, Nancy A., Keller, Gordon

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Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia von Yashiro-Ohtani, Yumi, Wang, Hongfang, Zang, Chongzhi, Arnett, Kelly L, Bailis, Will, Ho, Yugong, Knoechel, Birgit, Lanauze, Claudia, Louis, Lumena, Forsyth, Katherine S, Chen, Sujun, Chung, Yoonjie, Schug, Jonathan, Blobel, Gerd A, Liebhaber, Stephen A, Bernstein, Bradley E, Blacklow, Stephen C, Liu, Xiaole Shirley, Aster, Jon C, Pear, Warren S

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The unique target specificity of a nonpeptide chemokine receptor antagonist: selective blockade of two Th1 chemokine receptors CCR5 and CXCR3 von Gao, Ping, Zhou, Xu‐Yu, Yashiro‐Ohtani, Yumi, Yang, Yi‐Fu, Sugimoto, Naotoshi, Ono, Shiro, Nakanishi, Tsuyoshi, Obika, Satoshi, Imanishi, Takeshi, Egawa, Takeshi, Nagasawa, Takashi, Fujiwara, Hiromi, Hamaoka, Toshiyuki

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Modulating the strength and threshold of NOTCH oncogenic signals by mir-181a-1/b-1 von Fragoso, Rita, Mao, Tin, Wang, Song, Schaffert, Steven, Gong, Xue, Yue, Sibiao, Luong, Richard, Min, Hyeyoung, Yashiro-Ohtani, Yumi, Davis, Mark, Pear, Warren, Chen, Chang-Zheng

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Chimeric antigen receptor macrophages (CAR-M) sensitize HER2+ solid tumors to PD1 blockade in pre-clinical models von Pierini, Stefano, Gabbasov, Rashid, Oliveira-Nunes, Maria Cecilia, Qureshi, Rehman, Worth, Alison, Huang, Shuo, Nagar, Karan, Griffin, Crystal, Lian, Lurong, Yashiro-Ohtani, Yumi, Ross, Kayleigh, Sloas, Christopher, Ball, Michael, Schott, Benjamin, Sonawane, Poonam, Cornell, Linara, Blumenthal, Daniel, Chhum, Sotheavy, Minutolo, Nicholas, Ciccaglione, Kerri, Shaw, Lauren, Zentner, Isaac, Levitsky, Hyam, Shestova, Olga, Gill, Saar, Varghese, Bindu, Cushing, Daniel, Ceeraz DeLong, Sabrina, Abramson, Sascha, Condamine, Thomas, Klichinsky, Michael

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Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A von Yashiro-Ohtani, Yumi, He, Yiping, Ohtani, Takuya, Jones, Mary E, Shestova, Olga, Xu, Lanwei, Fang, Terry C, Chiang, Mark Y, Intlekofer, Andrew M, Blacklow, Stephen C, Zhuang, Yuan, Pear, Warren S

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Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals in Early T Cell Progenitors von Kobayashi, Michihiro, Nabinger, Sarah C., Bai, Yunpeng, Yoshimoto, Momoko, Gao, Rui, Chen, Sisi, Yao, Chonghua, Dong, Yuanshu, Zhang, Lujuan, Rodriguez, Sonia, Yashiro‐Ohtani, Yumi, Pear, Warren S., Carlesso, Nadia, Yoder, Mervin C., Kapur, Reuben, Kaplan, Mark H., Daniel Lacorazza, Hugo, Zhang, Zhong‐Yin, Liu, Yan

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Notch regulation of early thymocyte development von Yashiro-Ohtani, Yumi, Ohtani, Takuya, Pear, Warren S

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Active Notch1 Confers a Transformed Phenotype to Primary Human Melanocytes von PINNIX, Chelsea C, LEE, John T, YASHIRO-OHTANI, Yumi, NATHANSON, Katherine L, BENGSTON, Ana, POLLOCK, Pamela M, WEERARATNA, Ashani T, NICKOLOFF, Brian J, PEAR, Warren S, CAPOBIANCO, Anthony J, HERLYN, Meenhard, LIU, Zhao-Jun, MCDAID, Ronan, BALINT, Klara, BEVERLY, Levi J, BRAFFORD, Patricia A, MIN XIAO, HIMES, Benjamin, ZABIEROWSKI, Susan E

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Induction of surface CCR4 and its functionality in mouse Th2 cells is regulated differently during Th2 development von Morimoto, Yasunari, Bian, Yang, Gao, Ping, Yashiro‐Ohtani, Yumi, Zhou, Xu‐Yu, Ono, Shiro, Nakahara, Hirokazu, Kogo, Mikihiko, Hamaoka, Toshiyuki, Fujiwara, Hiromi

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IL-12 plays a pivotal role in LFA-1-mediated T cell adhesiveness by up-regulation of CCR5 expression von Mukai, Takao, Iwasaki, Masayuki, Gao, Ping, Tomura, Michio, Yashiro‐Ohtani, Yumi, Ono, Shiro, Murai, Masako, Matsushima, Kouji, Kurimoto, Masashi, Kogo, Mikihiko, Matsuya, Tokuzo, Fujiwara, Hiromi, Hamaoka, Toshiyuki

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A critical role for TCF-1 in T-lineage specification and differentiation von Weber, Brittany Nicole, Chi, Anthony Wei-Shine, Chavez, Alejandro, Yashiro-Ohtani, Yumi, Yang, Qi, Shestova, Olga, Bhandoola, Avinash

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Molecular Mechanisms Underlying Differential Contribution of CD28 Versus Non-CD28 Costimulatory Molecules to IL-2 Promoter Activation von Zhou, Xu-Yu, Yashiro-Ohtani, Yumi, Nakahira, Masakiyo, Park, Woong Ryeon, Abe, Ryo, Hamaoka, Toshiyuki, Naramura, Mayumi, Gu, Hua, Fujiwara, Hiromi

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Fusogenic liposomes efficiently deliver exogenous antigen through the cytoplasm into the MHC class I processing pathway von Nakanishi, Tsuyoshi, Hayashi, Akira, Kunisawa, Jun, Tsutsumi, Yasuo, Tanaka, Keiichi, Yashiro‐Ohtani, Yumi, Nakanishi, Mahito, Fujiwara, Hiromi, Hamaoka, Toshiyuki, Mayumi, Tadanori

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Notch Simultaneously Orchestrates Multiple Helper T Cell Programs Independently of Cytokine Signals von Bailis, Will, Yashiro-Ohtani, Yumi, Fang, Terry C., Hatton, Robin D., Weaver, Casey T., Artis, David, Pear, Warren S.

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Notch Directly Regulates Gata3 Expression during T Helper 2 Cell Differentiation von Fang, Terry C., Yashiro-Ohtani, Yumi, Del Bianco, Cristina, Knoblock, Dawson M., Blacklow, Stephen C., Pear, Warren S.

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c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma von Weng, Andrew P, Millholland, John M, Yashiro-Ohtani, Yumi, Arcangeli, Marie Laure, Lau, Arthur, Wai, Carol, Del Bianco, Cristina, Rodriguez, Carlos G, Sai, Hong, Tobias, John, Li, Yueming, Wolfe, Michael S, Shachaf, Cathy, Felsher, Dean, Blacklow, Stephen C, Pear, Warren S, Aster, Jon C

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T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1 von De Obaldia, Maria Elena, Bell, J Jeremiah, Wang, Xinxin, Harly, Christelle, Yashiro-Ohtani, Yumi, DeLong, Jonathan H, Zlotoff, Daniel A, Sultana, Dil Afroz, Pear, Warren S, Bhandoola, Avinash

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