Preclinical pharmacological profile of the selective 5-HT1F receptor agonist lasmiditan von Nelson, David L, Phebus, Lee A, Johnson, Kirk W, Wainscott, David B, Cohen, Marlene L, Calligaro, David O, Xu, Yao-Chang

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Room Temperature Asymmetric Allylic Trifluoromethylation of Morita–Baylis–Hillman Carbonates von Li, Yun, Liang, Fang, Li, Qian, Xu, Yao-chang, Wang, Quan-Rui, Jiang, Lei

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Conformational Preferences of π–π Stacking Between Ligand and Protein, Analysis Derived from Crystal Structure Data Geometric Preference of π–π Interaction von Zhao, Yuan, Li, Jue, Gu, Hui, Wei, Dongqing, Xu, Yao-chang, Fu, Wei, Yu, Zhengtian

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Discovery of selective N-[3-(1-methyl-piperidine-4-carbonyl)-phenyl]-benzamide-based 5-HT1F receptor agonists: Evolution from bicyclic to monocyclic cores von Zhang, Deyi, Blanco, Maria-Jesus, Ying, Bai-Ping, Kohlman, Daniel, Liang, Sidney X., Victor, Frantz, Chen, Qi, Krushinski, Joseph, Filla, Sandra A., Hudziak, Kevin J., Mathes, Brian M., Cohen, Michael P., Zacherl, DeAnna, Nelson, David L.G., Wainscott, David B., Nutter, Suzanne E., Gough, Wendy H., Schaus, John M., Xu, Yao-Chang

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Stereoselective, Oxidative C−C Bond Coupling of Naphthopyran Induced by DDQ:  Stereocontrolled Total Synthesis of Deoxyfrenolicin von Xu, Yao-Chang, Kohlman, Dan T, Liang, Sidney X, Erikkson, Chad

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Detecting S-adenosyl-l-methionine-induced conformational change of a histone methyltransferase using a homogeneous time-resolved fluorescence-based binding assay von Lin, Ying, Fan, Hong, Frederiksen, Mathias, Zhao, Kehao, Jiang, Lei, Wang, Zhaofu, Zhou, Shaolian, Guo, Weihui, Gao, Jun, Li, Shu, Harrington, Edmund, Meier, Peter, Scheufler, Clemens, Xu, Yao-Chang, Atadja, Peter, Lu, Chris, Li, En, Justin Gu, X.

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Oxidative C−C Bond-Forming Reaction of Electron-Rich Alkylbenzyl Ether with Trimethylvinyloxysilane von Ying, Bai-Ping, Trogden, Bridget G, Kohlman, Daniel T, Liang, Sidney X, Xu, Yao-Chang

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Preparation of 8-Amido-2-dimethylamino-1,2,3,4-tetrahydro-2-dibenzofurans and Several Fluorinated Derivatives via [3,3]-Sigmatropic Rearrangement of O-Aryloximes von Guzzo, Peter R, Buckle, Ronald N, Chou, Ming, Dinn, Sean R, Flaugh, Michael E, Kiefer, Anton D, Ryter, Kendal T, Sampognaro, Anthony J, Tregay, Steven W, Xu, Yao-Chang

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Lithiated Benzothiophenes and Benzofurans Require 2-Silyl Protection to Avoid Anion Migration von Hansen, Marvin M., Clayton, Marcella T., Godfrey, Alexander G., Grutsch Jr, John L., Keast, Sandra S., Kohlman, Dan T., McSpadden, Andreea R., Pedersen, Steven W., Ward, Jeffrey A., Xu, Yao-Chang

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Selective deprotection of alkyl esters using magnesium methoxide von Yao-Chang, Xu, Bizuneh, Amsalu, Walker, Clint

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Regio- and stereoselective DDQ-induced oxidative coupling of isochromans and isothiochroman with alcohols von Xu, Yao-Chang, Lebeau, Elaine, Gillard, John W., Attardo, Giorgio

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Selective deprotection of esters using magnesium and methanol von Xu, Yao-Chang, Lebeau, Elaine, Walker, Clint

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Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT 1F receptor agonists von Zhang, Deyi, Kohlman, Dan, Krushinski, Joseph, Liang, Sidney, Ying, Bai-Ping, Reilly, John E., Dinn, Sean R., Wainscott, David B., Nutter, Suzanne, Gough, Wendy, Nelson, David L.G., Schaus, John M., Xu, Yao-Chang

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Abstract B151: Discovery and characterization of a novel small molecule brain penetrant PD-L1 inhibitor von Zhang, Yongxian, Zhang, Mingming, Zhao, Baowei, Yu, Hongping, Xu, Yao-Chang, Chen, Zhui, Ying, Haiyan

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Abstract LB317: Discovery and characterization of a next-generation FGFR inhibitor overcoming FGFR resistant mutations von Ying, Haiyan, Xin, Wenqun, Deng, Haibing, Zhao, Yuan, Yu, Hongping, Chen, Zhui, Xu, Yao-chang

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Abstract LB-A17: Discovery and characterization of a novel small molecule antagonist of PD-L1 von Ying, Haiyan, Yang, Fei, Zhang, Mingming, Zhang, Yongxian, Zhao, Yuan, Chen, Xin, Zhang, Lei, Yu, Hongping, Chen, Zhui, Xu, Yao-chang

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Abstract C130: Discovery and characterization of an MTA-cooperative and brain-penetrant PRMT5 inhibitor von Pan, Weiling, Wang, Hui, Qi, Fangfei, Deng, Haibing, Yang, Fei, Yu, Hongping, Xu, Yao-Chang, Chen, Zhui, Ying, Haiyan

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Abstract LB328: Discovery & characterization of a next-generation FGFR4 inhibitor overcoming resistant mutations von Ying, Haiyan, Zhang, Nannan, Deng, Haibing, Yang, Fei, Xin, Wenqun, Shen, Bin, Yu, Hongping, Chen, Zhui, Xu, Yao-chang

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DDQ-Induced, Anomeric Specific, and Diastereoselective Benzylic Glycosidation: A Novel Approach to Heterocyclic Anthracycline Antibiotics von Xu, Yao-Chang, Lebeau, Elaine, Attardo, Giorgio, Myers, Peter L, Gillard, John W

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Stereoselective aldol addition reactions of Fischer carbene complexes via electronic tuning of the metal center for enolate reactivity von Wulff, William D., Anderson, Benjamin A., Toole, Amanda J., Xu, Yao-Chang

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